Results 61 to 70 of about 22,986 (208)
Mechanistic, energetic and structural studies of single-walled carbon nanotubes functionalized with penicillamine [PDF]
Using the density functional theory, the possible non-covalent interactions and six mechanisms of covalent functionalization of the drug penicillamine with functionalized carbon nanotubes (CNT) were investigated.
Shaki Hosein +4 more
doaj +1 more source
Treating Rheumatoid Arthritis yesterday and today [PDF]
Rheumatoid arthritis is a chronic, systemic inflammatory disorder that mainly affects joints. It is the most common form of inflammatory joint disease, and the second commonest joint disease, osteoarthritis being the commonest.
Mallia, Carmel
core
Recent progress on stimuli‐responsive chitosan‐based biomaterials as drug carriers
This review discusses the recent progress in chitosan‐based drug delivery systems that respond to pH, redox, enzymes, reactive oxygen species, and combined stimuli. It examines design strategies, key mechanisms, and therapeutic applications, and also addresses current challenges while suggesting future approaches to enhance clinical translation and ...
Changlu Xu +4 more
wiley +1 more source
Background and aim The increasing use of nuclear technology has increased the risk of exposure to radiation. Exposure to radiation induces harms to human beings. The blood and blood-forming organs are one of the most sensitive to radiation.
Yasser M.M El-Dessouky +2 more
doaj +1 more source
Background: Lead is a potent toxin that targets heme synthesis and some antioxidant enzymes that induce oxidative stress. Lead exposure remains one of the significant health concerns all over the world.
Alireza Badsar +5 more
doaj +1 more source
Abstract Wilson disease (WD) is an autosomal recessive disorder of hepatic copper metabolism with varied clinical presentations. We describe a 15‐year‐old male referred for elevated aminotransferases, burning facial pruritis, scalp dysesthesias, and chronic bilateral lower extremity edema.
Tierra L. R. Mosher +2 more
wiley +1 more source
Sir John Cornforth AC CBE FRS: his synthetic work [PDF]
Sir John Cornforth’s work on the synthesis of cholesterol and penicillamine, on the chemistry of oxazoles, the stereochemistry of the synthesis of alkenes, the synthesis of abscisic acid and of dibenzophospholes as mimics of enzyme action, is ...
Abraham E.P. +15 more
core +1 more source
The utility of whole exome sequencing in diagnosing Wilson disease: A case report
Abstract Wilson disease (WD) is an autosomal recessive disorder of copper metabolism caused by mutations in the ATP7B gene, resulting in toxic copper accumulation in the body. Diagnosis is typically based on biochemistries, including low serum ceruloplasmin and elevated 24‐h urine copper excretion, with Kayser–Fleischer (KF) rings being a supportive ...
Mihir J. Palan +4 more
wiley +1 more source
ABSTRACT Background Challenges in establishing clinical conventional in vitro fertilization (IVF) in horses include variation in sperm and oocyte quality, which can be affected by mare age. Extended preincubation of stallion spermatozoa has resulted in successful IVF.
Raul A. Gonzalez‐Castro +6 more
wiley +1 more source
Novel cadmium oxide nanoparticles based sensor for the detection of penicillamine (PA) in aqueous solution has been developed. Cyclic voltammetry at potential range -1.1 to 1.1V from aqueous buffer solution (pH 7) containing CdO produced a well-defined ...
Balal Khalilzadeh +6 more
doaj +1 more source

