Results 81 to 90 of about 16,893 (203)

N-Formylpenicillamine and penicillamine as degradation products of penicillins in solution

open access: yes, 1986
The degradation of several penicillins in unbuffered aqueous solution produces N-formylpenicillamine, in some cases in high yield. Very little or no penicillamine is formed under these conditions.
A C Marshall, A E Bird, K R Jennings
core   +1 more source

D-penicillamine and the transport of L-cystine by rat and human renal cortical brush-border membrane vesicles

open access: yes, 1990
Brush-border membrane vesicles (BBMV) were prepared from rat and human renal cortical tissue by magnesium aggregation and differential centrifugation, and the uptake of L-cystine, L-cysteine, and L-cysteine-D-penicillamine were assessed by a rapid ...
T. J. Furlong, S. Posen
core   +1 more source

The treatment of rheumatoid arthritis with D-penicillamine. Preliminary report [PDF]

open access: yes, 1978
Twenty patients with classical or definite rheumatoid arthritis were treated with D-Penicillamine. Favorable responses were observed in 75% of the patients. Significant improvement in clinical parameters, such as ESR, CRP, titers of rheumatoid factor and
Takasugi, Kiyoshi   +3 more
core   +1 more source

Mechanistic Investigation of Penicillamine-induced Autoimmunity: Covalent Binding of Penicillamine to Macrophages, Involvement of Th17 cells, and Its Relation to Idiosyncratic Drug-induced Liver Injury [PDF]

open access: yes, 2010
The mechanisms of idiosyncratic drug reactions (IDRs) are unknown; however, most appear to be immune-mediated. Their idiosyncratic nature and the paucity of animal models make mechanistic studies very difficult.
Li, Jinze
core   +1 more source

D-penicillamine and immune complex deposition

open access: yes, 1978
suMMARY Dense, granular immunoglobulin deposits have been identified at the epidermo-dermal junction in 4 out of 10 patients who developed toxic reactions to D-penicillamine therapy for rheu-matoid arthritis.
B. Smith   +3 more
core  

Nephrotic syndrome after treatment with D-penicillamine in a patient with Wilson’s disease

open access: yesRomanian Journal of Laboratory Medicine, 2014
Wilson’s disease is an inherited autosomal recessive disorder of copper balance leading to accumulation of copper mainly in liver and brain result from absent or reduced function of copper-transporting P-type ATPase.
Kostadinova Anna D.   +3 more
doaj   +1 more source

Penicillamine Induced Lupus-Like Syndrome: A Case Report

open access: yes, 2008
Several drugs have been suggested to cause lupus-like syndrome. However, penicillamine-induced lupus-like syndrome has only rarely been reported in patients with Wilson's disease.
倪衍玄;江伯倫   +1 more
core  

CONTROLLED MULTI-CENTER TRIAL OF TIOPRONIN AND D-PENICILLAMINE FOR RHEUMATOID-ARTHRITIS

open access: yes, 1982
Fifty-seven patients took part in a controlled double-blind trial between tiopronin and D-penicillamine as basic treatment for rheumatoid arthritis. Thirty-nine (19 receiving tiopronin, 20 receiving D-penicillamine) completed the trial after 1 year. Both
COLAMUSSI V   +9 more
core   +1 more source

Penicillamine determination using a tyrosinase micro-rotating biosensor

open access: yes, 2006
Penicillamine determination using a tyrosinase micro-rotating ...
Angel Torriero (13058478)   +4 more
core  

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