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Hepatotoxicity related to antirheumatic drugs
Nature Reviews Rheumatology, 2011Antirheumatic agents are among commonly used drugs associated with adverse hepatic reactions. Sulfasalazine and azathioprine are among the most important causes of acute hepatotoxicity. Because such a large number of people take NSAIDs, even the rare occurrence of hepatotoxicity from these agents might contribute substantially to the total burden of ...
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Studies on lysosome stabilization by antirheumatic drugs
European Journal of Pharmacology, 1970Abstract Differential centrifugation was used to isolate a lysosome containing fraction from rat liver homogenate. The influence of cortisone, hydrocortisone, salicylate and chloroquine on the stability of the lysosomes was tested using different labilization procedures.
A. Jørgensen, John Hyttel
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Antirheumatic drug reactions in the lung
Baillière's Clinical Rheumatology, 1993Drug-induced lung disease during treatment with antirheumatic drugs should be considered in all patients receiving these agents who develop new pulmonary symptoms. When a potential drug-related reaction is identified, the possible offending agents should be discontinued, appropriate respiratory support initiated, and a thorough investigation for other ...
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Antirheumatic drugs in older adults and polypharmacy issues
Zeitschrift für Gerontologie und Geriatrie (Print), 2021İ. Coşkun Benlidayı +1 more
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Antirheumatic drugs in pregnancy and lactation
2013Antirheumatic drugs in pregnancy and lactation are increasingly a common clinical dilemma. With the shift towards early, aggressive control of autoimmune diseases and with the advent of newer therapeutic agents, there is a need to understand the effects of these medicines in pregnancy and lactation, on fertility in both men and women, and on the ...
Tarnya Marshall +3 more
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Antirheumatic drugs in pregnancy and lactation
2016Antirheumatic drugs in pregnancy and lactation are increasingly a common clinical dilemma. With the shift towards early, aggressive control of autoimmune diseases and with the advent of newer therapeutic agents, there is a need to understand the effects of these medicines in pregnancy and lactation, on fertility in both men and women, and on the ...
Poonam Sharma +2 more
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Pulmonary complications of antirheumatic drug therapy
Seminars in Arthritis and Rheumatism, 1990Drug-induced pulmonary disease should be considered in all patients receiving these antirheumatic agents who develop new pulmonary symptoms. When a drug reaction is suspected, the possible offending agents should be discontinued, required respiratory support instituted, and infection or other pulmonary processes excluded.
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Antirheumatic drug therapy in the elderly
1992In developed nations about 10 percent of the population are elderly, defined as 65 years or older [1]. Predictions forecast a doubling of this percentage by the year 2030 [2]. At present the elderly use approximately 75 percent of doctors’ time and require 20–40 prescriptions per person annually [3].
Walter F. Kean, W. Watson Buchanan
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Antirheumatic drugs and eicosanoid synthesis
Scandinavian Journal of Rheumatology, 1988H. Isomakp +5 more
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