Effects of antirheumatic agents on cytokines [PDF]
Seminars in Arthritis and Rheumatism, 1996 A review of the literature concerning the effects of traditional antirheumatic drugs on cytokines and the cytokine and anticytokine approaches already used in the therapy of rheumatoid arthritis (RA) is presented. Many antirheumatic drugs are capable of cytokine modulation in vitro. Corticosteroids inhibit the transcription of a broad spectrum of genes
P Barrera +2 more
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Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021 Background Cardiovascular disease is the most common cause of death in patients with rheumatoid arthritis. It is believed that using disease‐modifying antirheumatic drugs (DMARDs) to control inflammation can reduce the risk of cardiovascular disease.
Chung‐Yuan Hsu +8 more
doaj +3 more sources
Diabetes-Modifying Antirheumatic Drugs: The Roles of DMARDs as Glucose-Lowering Agents
Medicina, 2022 Systemic inflammation represents a shared pathophysiological mechanism which underlies the frequent clinical associations among chronic inflammatory rheumatic diseases (CIRDs), insulin resistance, type 2 diabetes (T2D), and chronic diabetes complications,
Marco Infante +6 more
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Thyroid Autoimmunity and Function after Treatment with Biological Antirheumatic Agents in Rheumatoid Arthritis [PDF]
Frontiers in Endocrinology, 2017 Sofie Bliddal +2 more
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Clinical Consensus Statement: Perioperative Management of Prothrombotics, Antiplatelets, Anticoagulants, DMARDs and Biologics in Elective Podiatric Surgery [PDF]
Journal of Foot and Ankle ResearchIntroduction A substantial body of literature exists on the perioperative management of pharmacological agents specifically prothrombotic agents, antiplatelets, anticoagulants and disease‐modifying antirheumatic drugs (DMARDs) aimed at mitigating risks ...
Jade Tang +5 more
doaj +2 more sources
Effects of Abatacept in patients with rheumatoid arthritis and cancer risk [PDF]
Reviews in Clinical Medicine, 2023 Introduction: As a chronic autoimmune disease, Rheumatoid arthritis (RA) affects the joints. Studies have shown a complex and challenging link between cancer and RA.
Saba Homapoor +2 more
doaj +1 more source
Arthritis Research & Therapy, 2023 Background This study sought to evaluate the efficacy and safety of tofacitinib in patients with rheumatoid arthritis with distinct treatment histories. Methods Pooled phase II/III trial data from patients who received tofacitinib 5 or 10 mg twice daily ...
John Tesser +6 more
doaj +1 more source
Two-year clinical outcomes after discontinuation of long-term golimumab therapy in Korean patients with rheumatoid arthritis [PDF]
The Korean Journal of Internal Medicine, 2022 Background/Aims The aim of this study was to investigate long-term post-discontinuation outcomes in patients with rheumatoid arthritis (RA) who had been treated with tumor necrosis factor-α inhibitors (TNF-αi) which was then discontinued.
Kichul Shin +14 more
doaj +1 more source
Simplified disease activity changes in real-world practice: a nationwide observational study of seropositive rheumatoid arthritis patients with moderate-to-high disease activity [PDF]
The Korean Journal of Internal Medicine, 2020 Background/Aims The objective of this study was to compare changes in the simplified disease activity index (SDAI) between biologic (b) and conventional (c) disease-modifying antirheumatic drugs (DMARD) users with seropositive rheumatoid arthritis (RA ...
Kichul Shin +23 more
doaj +1 more source