CARDIOVASCULAR DISEASES IN RHEUMATOID ARTHRITIS: LATEST DATA
The paper gives the latest data on the impact of traditional cardiovascular risk factors, chronic inflammation, antirheumatic therapy (disease-modifying antirheumatic drugs and biological agents) on the cardiovascular system.
T. V. Popkova+2 more
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Effects of the anti-RANKL antibody denosumab on joint structural damage in patients with rheumatoid arthritis treated with conventional synthetic disease-modifying antirheumatic drugs (DESIRABLE study): a randomised, double-blind, placebo-controlled phase 3 trial. [PDF]
ObjectiveTo evaluate the efficacy of denosumab in suppressing joint destruction when added to conventional synthetic disease-modifying antirheumatic drug (csDMARD) therapy in patients with rheumatoid arthritis (RA).MethodsThis was a multi-centre ...
Genant, Harry K+9 more
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Rheumatoid arthritis is a chronic inflammatory joint disease, which can cause cartilage and bone damage as well as disability. Early diagnosis is key to optimal therapeutic success, particularly in patients with well-characterised risk factors for poor ...
Aletaha, Daniel+2 more
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Synergistic drug combinations from electronic health records and gene expression. [PDF]
ObjectiveUsing electronic health records (EHRs) and biomolecular data, we sought to discover drug pairs with synergistic repurposing potential. EHRs provide real-world treatment and outcome patterns, while complementary biomolecular data, including ...
Chen, William+19 more
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Antirheumatic drugs and reproduction in women and men with chronic arthritis. [PDF]
The impact of rheumatic disease on fertility and reproduction can be remarkable. Many disease-related factors can influence patients' sexual functioning, perturb fertility and limit family planning. Antirheumatic pharmacological treatment can also have a
Agosti, M+4 more
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Treatment of experimental amyloidosis with antirheumatic drugs
Background. Because at present there is no known specific effective therapy for secondary amyloidosis, the aim of this study was to determine whether antirheumatic drugs inhibit the development of experimental AA amyloidosis induced in C57BL/6 mice by ...
Laima LEONAVIČIENĖ+4 more
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Place of enalapril in treatment of patients with systemic lupus erythematosus and systemic sclerosis
Lupus erythematosus (SLE) and systemic sclerosis (SS). Methods. 45 SLE and 44 SS pts were included. Some of them received antirheumatic drugs in combination with enalapril other were treated with antirheumatic drugs only. The pts were examined before and
L K Kozlova, V V Bagirova
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Fluorescence optical imaging for treatment monitoring in patients with early and active rheumatoid arthritis in a 1-year follow-up period [PDF]
BACKGROUND: Fluorescence optical imaging (FOI) enables visualization of inflammation in the hands in rheumatic joint diseases with currently a lack of long-term follow-up studies.
Backhaus, Marina+10 more
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Prescription pattern in patients with rheumatoid arthritis in a teaching tertiary care hospital
Objective: This study was conducted, with the aim to analyze the pattern of use of antirheumatic drugs in a Tertiary Care Hospital in Delhi, India. Methodology: The study was carried out in 150 patients who were on treatment with antirheumatic drugs at ...
Akhil Dahiya+3 more
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Current issues in the management of patients with HIV infection and rheumatic diseases
According to experts, the human immunodeficiency virus (HIV) epidemic has a steady downward trend, but the attention of the medical community to this problem is not waning.
G. I. Gridneva, B. S. Belov
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