Immune cells and stromal cells undergo metabolic reprogramming in both rheumatoid and osteoarthritis. This review summarises current evidence on the metabolic changes within and the crosstalk between immune and stromal cells in these diseases. In addition, we explore the therapeutic potential of targeting metabolic processes for the treatment of ...
Órlaith C. Henry, Luke A. J. O'Neill
wiley +1 more source
A case-control study of anaemia in patients with rheumatoid arthritis treated with disease-modifying antirheumatic drugs in an adult population in the US: prevalence and impact on healthcare utilisation [PDF]
Chenglong Han+4 more
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This study investigates the risk of serious infections (SIs) in patients treated with biologic or targeted‐synthetic disease‐modifying antirheumatic drugs (b/tsDMARDs) in Qatar. Out of 1092 patients, 86 (7.9%) experienced SIs, with adalimumab and infliximab associated with higher SI rates.
Sreethish Sasi+12 more
wiley +1 more source
Rheumatoid Atlantoaxial Subluxation Can Be Prevented by Intensive Use of Traditional Disease Modifying Antirheumatic Drugs [PDF]
Markku Kauppi+10 more
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N‐heterocyclic carbenes (NHCs) exhibit promising biological activity, which can be enhanced by coordination with coinage metals. This review explores the antimicrobial activity of azolium salts and their corresponding NHC complexes of Ag, Au, and Cu. Silver(I)‐NHC complexes are the more prominent biologically active compounds.
Ngonidzashe Ruwizhi+3 more
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Initiation of Disease-Modifying Antirheumatic Drugs in Older Medicare Beneficiaries With New Diagnosis of Late-Onset Rheumatoid Arthritis. [PDF]
Lee J+5 more
europepmc +1 more source
Abstract Granulocyte and monocyte adsorptive apheresis (GMA) selectively removes activated granulocytes and monocytes from the peripheral blood. In 2012, GMA was approved in Japan as a treatment for generalized pustular psoriasis and localized pustular psoriasis or palmoplantar pustulosis (PPP).
Namiko Abe+6 more
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Efficacy and toxicity of old and new disease modifying antirheumatic drugs
Peter Tugwell
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Plasma Adiponectin in Patients with Active, Early, and Chronic Rheumatoid Arthritis Who Are Steroid- and Disease-Modifying Antirheumatic Drug-Naive Compared with Patients with Osteoarthritis and Controls [PDF]
Trine Bay Laurberg+11 more
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In Switzerland, most dispensed medications with teratogenic effect debated or proven were in the group of weak teratogenicity level. Reassuringly, many women discontinue treatment with potential teratogens before pregnancy. Abstract Introduction Exposure to potentially teratogenic medications during pregnancy is underinvestigated in Switzerland.
Carole A. Marxer+5 more
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