Results 81 to 90 of about 42,703 (308)

Aliskiren, tadalafil, and cinnamaldehyde alleviate joint destruction biomarkers; MMP-3 and RANKL; in complete Freund's adjuvant arthritis model: Downregulation of IL-6/JAK2/STAT3 signaling pathway

Saudi Pharmaceutical Journal, 2020
Rheumatoid arthritis (RA) is an autoimmune inflammatory disease, which is accompanied by progressive joint damage and disability. The intolerability of conventional antirheumatic drugs by some patients necessitates the search for effective antirheumatic ...
Amany A. Azouz, Esraa Saleh, Ali A. Abo-Saif   +2 more
doaj   +1 more source

Neonatal-onset multisystem inflammatory disease responsive to interleukin-1 beta inhibition [PDF]

, 2006
BACKGROUND:Neonatal-onset multisystem inflammatory disease is characterized by fever, urticarial rash, aseptic meningitis, deforming arthropathy, hearing loss, and mental retardation.
Adams, BS, Aksentijevich, I, Beitz, LO, Brewer, C, Butman, JA, Canna, SW, Cole, JL, Dailey, NJ, Fuhlbrigge, RC, Gardner, G, Gelabert, A, Goldbach-Mansky, R, Hannan, WP, Haverkamp, MH, Hawkins, PN, Hill, S, Hoffmann, SC, Holland, SM, Horn, W, Jarvis, JN, Jones, J, Karp, BI, Kastner, DL, Kim, HJ, Moore, TL, O'Neil, K, Paul, SM, Penzak, SR, Pham, TH, Pucino, F, Rubin, BI, Shaham, B, Snyder, C, Stein, L, Turner, ML, Vehe, RK, Warren, RW, Wesley, RA, Wiggs, E, Zalewski, C   +39 more
core  

Comparative effectiveness of adalimumab and etanercept for rheumatoid arthritis in the Brazilian Public Health System [PDF]

, 2016
Aim: Biological disease-modifying antirheumatic drugs (bDMARDs) are used to treat rheumatoid arthritis (RA) with adalimumab and etanercept the most used bDMARDs in Brazil.
Acurcio, Francisco De Assis, Almeida, Alessandra Maciel, Alvares, Juliana, Bennie, Marion, De Oliveira, Haliton Alves, Dos Santos, Jéssica Barreto Ribeiro, Godman, Brian, Guerra, Augusto Afonso, Kakehasi, Adriana Maria   +8 more
core   +1 more source

Recognition of Glycine Versus Nonglycine Citrulline Motifs Dictating the HLA Class II Association of Anticitrullinated Protein Antibodies: Insights From Autoantibody Profiling of 6,900 Scandinavian Patients With Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis (RA)–associated anticitrullinated protein antibodies (ACPAs) target various antigens by binding short citrulline amino acid motifs, resulting in heterogeneous ACPA profiles among patients. Here we analyzed ACPA patterns by recognized citrulline motifs in relation to the RA risk factors HLA‐DRB1 shared epitope (SE) alleles
Linda Mathsson Alm, Helga Westerlind, Isabel Gehring, Monika Hansson, Nasim Ghasemzadeh, Jessica Rojas‐Restrepo, Saedis Saevarsdottir, Joe Sexton, Siri Lillegraven, Espen Haavardsholm, Bente Glintborg, Hilde Berner Hammer, Tore K. Kvien, Merete Lund Hetland, Leonid Padyukov, Swedish Rheumatology Quality Register Biobank Study Group (SRQb), The Danish Rheumatologic Biobank Study Group, Johan Askling, Caroline Grönwall   +18 more
wiley   +1 more source

Potenciais interações medicamentosas em pacientes com artrite reumatoide Potential drug interactions in patients with rheumatoid arthritis

Revista Brasileira de Reumatologia, 2011
INTRODUÇÃO: O termo polifarmácia, ou seja, a utilização concomitante de múltiplos fármacos pelo mesmo indivíduo vem sendo amplamente associado a pacientes institucionalizados e idosos, no entanto pode ocorrer em grupos de pacientes portadores de doenças ...
Fabíola Bagatini, Carine Raquel Blatt, Gabriela Maliska, Gunter Voges Trespash, Ivânio Alves Pereira, Adriana Fontes Zimmermann, Bernd Heinrich Storb, Mareni Rocha Farias   +7 more
doaj   +1 more source

Impact of biological agents and tissue engineering approaches on the treatment of rheumatic diseases [PDF]

, 2010
The treatment of rheumatic diseases has been the focus of many clinical studies aiming to achieve the best combination of drugs for symptom reduction.
Martins, Albino, Neves, N. M., Reis, R. L., Silva, Marta Alves da, Teixeira, A. A.   +4 more
core   +1 more source

Recurrence Risk in Pediatric Noninfectious Uveitis During Adalimumab Tapering: An International Multicenter Retrospective Study

Arthritis &Rheumatology, EarlyView.
Objective This study aims to assess the risk of noninfectious uveitis (NIU) relapse in pediatric patients undergoing adalimumab (ADA) tapering, evaluating potential predictors of such risk. Methods We conducted a multicenter retrospective cohort study involving pediatric patients with NIU who underwent ADA tapering due to inactive uveitis.
Achille Marino, Maria Vittoria Cicinelli, Elisabetta Miserocchi, Stefania Costi, Francesco Baldo, Maurizio Virgilio Gattinara, Pierluigi Scandale, Scott D. Smith, Debra A. Goldstein, Dina Baddar, Terese K. A. Gerges, Timothy M. Janetos, Matilde Ruiz‐Cruz, Kazuichi Maruyama, Massimiliano Serafino, Paola Camicione, Vishali Gupta, Radgonde Amer, Emilio M. Dodds, Sebastian Inchauspe, Marion R. Munk, Ester Carreño, Soon‐Phaik Chee, Aniruddha Agarwal, Ariel Schlaen, Ramiro A. Gómez, Cristobal A. Couto, Moncef Khairallah, Piergiorgio Neri, Cecilia B. Chighizola, Roberto F. Caporali, Francesco Pichi   +31 more
wiley   +1 more source

Use of healthcare administrative claims data in observational studies of antirheumatic drug effects on pregnancy outcomes: A scoping review.

PLoS ONE
The safety of antirheumatic drugs in pregnancy and their impact on maternal and neonatal outcomes are understudied. Despite pregnant individuals being excluded from clinical trials, their continued use of medications raises the importance of addressing ...
Shenthuraan Tharmarajah, Araniy Santhireswaran, Yasmeen Ameeriar, Lisa M McCarthy, Dharini Mahendira, Howard Berger, Mina Tadrous, Sara J T Guilcher   +7 more
doaj   +1 more source

Is vaccination against viral hepatitis B safe and immunogenic in patients with rheumatic diseases?

Современная ревматология
Impressive successes have been achieved in the fight against viral hepatitis B (HBV), but victory over this infection has not yet been achieved. According to various estimates, there are 6–12.5 times more patients with resolved HBV who are carriers of ...
G. I. Gridneva, B. S. Belov, E. S. Aronova   +2 more
doaj   +1 more source

Hypomethylation of CYP2E1 and DUSP22 Promoters Associated With Disease Activity and Erosive Disease Among Rheumatoid Arthritis Patients. [PDF]

, 2018
OBJECTIVE:Epigenetic modifications have previously been associated with rheumatoid arthritis (RA). In this study, we aimed to determine whether differential DNA methylation in peripheral blood cell subpopulations is associated with any of 4 clinical ...
Barcellos, Lisa F, Chernitskiy, Vladimir, Criswell, Lindsey A, Graf, Jonathan, Harrison, Ruby, Holingue, Calliope, Imboden, John, Link, Thomas, Mok, Amanda, Quach, Diana, Quach, Hong L, Rhead, Brooke, Shao, Xiaorong, Sinclair, Elizabeth   +13 more
core   +1 more source