Results 321 to 330 of about 263,255 (408)

Molecular Profiling of Mouse Models of Loss or Gain of Function of the KCNT1 (Slack) Potassium Channel and Antisense Oligonucleotide Treatment. [PDF]

Biomolecules
Sun F, Wang H, Wu J, Quraishi IH, Zhang Y, Pedram M, Gao B, Jonas EA, Nguyen V, Wu S, Mabrouk OS, Jafar-Nejad P, Kaczmarek LK.   +12 more
europepmc   +1 more source

Therapeutic effect of intracolonically administered nuclear factorκB (p65) antisense oligonucleotide on mouse dextran sulphate sodium (DSS)-induced colitis

, 2000
Mitsuyuki Murano, Kentaro Maemura, I Hirata, Ken Toshina, Takeshi Nishikawa, Norihiro Hamamoto, S. Sasaki, Osamu Saitoh, Ken‐ichi Katsu   +8 more
openalex   +2 more sources

PUF60‐Regulated Isoform Switching of MAZ Modulates Gastric Cancer Cell Migration

Cancer Medicine, Volume 14, Issue 11, June 2025.
ABSTRACT Background As an essential transcription factor, Myc‐associated zinc‐finger protein (MAZ) is frequently upregulated in many human tumors and is a well‐documented oncogene. However, we found high expression of MAZ was closely associated with good survival outcomes in patients with stomach adenocarcinoma (STAD), and the underlying mechanism ...
Dong Xing, Ting Zhao, Chenchen Mao, Zheng Han, Wanxia Cai, Teming Zhang, Dianfeng Mei, Wangkai Xie, Jiaye Yu, Zhonghan Wu, Zhiyuan Chen, Shiyu Feng, Xian Shen, Xiangyang Xue, Dan Xiang   +14 more
wiley   +1 more source

Bcl-2 Antisense Oligonucleotides (G3139) Inhibit Merkel Cell Carcinoma Growth in SCID Mice

, 2000
Hermine Schlagbauer‐Wadl, Gabriele Klosner, Elisabeth Heere‐Ress, Stefan Waltering, Ingrid Moll, Klaus Wolff, Hubert Pehamberger, Burkhard Jansen   +7 more
openalex   +1 more source

Peptide–Oligonucleotide Conjugates: Catalytic Preparation in Aqueous Solution or On‐Column

Current Protocols, Volume 5, Issue 6, June 2025.
Abstract Peptide–oligonucleotide conjugates (POCs) are synthesized through a novel catalytic and sustainable approach. The amide coupling between peptide and oligonucleotide is facilitated by 1,4‐diazabicyclo[2.2.2]octane (DABCO) as catalyst and 2‐chloro‐4,6‐dimethoxy‐1,3,5‐triazine (CDMT) as a stoichiometric activating agent.
Marion Gras, Michael Smietana, Pauline Adler   +2 more
wiley   +1 more source

Preparing for Patient-Customized N-of-1 Antisense Oligonucleotide Therapy to Treat Rare Diseases. [PDF]

Genes (Basel)
Wilton-Clark H, Yan E, Yokota T, Yokota T.   +3 more
europepmc   +1 more source

Abstracts

Molecular Oncology, Volume 19, Issue S1, Page 1-895, June 2025.
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Tumor Diagnosis and Treatment Based on Stimuli‐Responsive Aggregation of Gold Nanoparticles

Exploration, Volume 5, Issue 3, June 2025.
This review summarizes the current strategies for inducing gold nanoparticles aggregation and its advances in tumor diagnosis and treatment. The authors hope this review can provide a valuable reference for the further development of AuNPs clinical applications.
Xiaowei Chang, Huaiyu Wang, Xin Chen
wiley   +1 more source

New horizons in the pharmacological management of venous thromboembolism

HemaSphere, Volume 9, Issue 6, June 2025.
Abstract Many patients suffer from venous thromboembolism (VTE) and its consequences. Despite substantial advancements with the introduction of direct oral anticoagulants (DOACs), patients and clinicians still encounter challenges in the acute and long‐term management of VTE, such as recurrent events, anticoagulant‐related bleeding complications, and ...
Andreas Verstraete, Quentin Van Thillo, Thomas Vanassche, Peter Verhamme   +3 more
wiley   +1 more source

Strategies to improve the design of gapmer antisense oligonucleotide on allele-specific silencing. [PDF]

Mol Ther Nucleic Acids
Aguti S, Cheng S, Ala P, Briggs S, Muntoni F, Zhou H.   +5 more
europepmc   +1 more source