Results 21 to 30 of about 127,002 (321)
Antisense oligonucleotides for neurodegeneration [PDF]
Science, 2020 Promising clinical results for Huntington's disease give hope for other ...
Leavitt, BR, Tabrizi, SJ
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Antisense oligonucleotides for the arterial hypertension mechanisms study and therapy
Вавиловский журнал генетики и селекции, 2018 Arterial hypertension is one of the most common chronic diseases in adults all over the world. This pathology can not only reduce patients’ life quality, but can also be accompanied by a number of complications.
L. O. Klimov +4 more
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Microbial Cell Factories, 2023 Research development in the precise control of gene expression in plant cells is an emerging necessity that would lead to the elucidation of gene function in these biological systems.
Hossein Alishah Aratboni +5 more
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Antibiotics, 2023 Antimicrobial drug resistance has emerged as a significant challenge in contemporary medicine due to the proliferation of numerous bacterial strains resistant to all existing antibiotics.
Nikolet Pavlova +2 more
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Regulation of metabolism by miR-378 [PDF]
, 2014 The present invention provides a method of regulating fatty acid metabolism in a cell by contacting the cell with a modulator of miR-378 and/or miR-378* activity or expression.
Carrer, Michele, Olson, Eric N.
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Targeting TGFβ Signaling to Address Fibrosis Using Antisense Oligonucleotides
Biomedicines, 2018 Fibrosis results from the excessive accumulation of extracellular matrix in chronically injured tissue. The fibrotic process is governed by crosstalk between many signaling pathways.
James T. March +6 more
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Generation of Choline for Acetylcholine Synthesis by Phospholipase D Isoforms [PDF]
, 2001 DEDICATION: This article is dedicated to the memory of Sue Kim Hanson, a graduate student in the department of Pathology and Laboratory Medicine at Boston University School of Medicine, who perished in the terrorist attacks of September 11, 2001 ...
Blusztajn, Jan Krzysztof +2 more
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Consequences of Making the Inactive Active Through Changes in Antisense Oligonucleotide Chemistries
Frontiers in Genetics, 2019 Antisense oligonucleotides are short, single-stranded nucleic acid analogues that can interfere with pre-messenger RNA (pre-mRNA) processing and induce excision of a targeted exon from the mature transcript.
Khine Zaw +13 more
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Site Selective Antibody-Oligonucleotide Conjugation via Microbial Transglutaminase. [PDF]
, 2019 Nucleic Acid Therapeutics (NATs), including siRNAs and AntiSense Oligonucleotides (ASOs), have great potential to drug the undruggable genome. Targeting siRNAs and ASOs to specific cell types of interest has driven dramatic improvement in efficacy and ...
Cui, Xianshu +6 more
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Taking control of gene expression with light-activated oligonucleotides
BioTechniques, 2007 The recent development of caged oligonucleotides that are efficiently activated by ultraviolet (UV) light creates opportunities for regulating gene expression with very high spatial and temporal resolution.
Ivan J. Dmochowski, XinJing Tang
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