Results 161 to 170 of about 57,561 (211)
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Human Fibrinopeptides as Antithrombins
Thrombosis and Haemostasis, 1973SummaryHuman fibrinopeptides have been isolated from purified human fibrinogen and investigations performed on their reactions with thrombin and platelets. Fibrinopeptides A and B had an inhibitory action against the proteolytic action of thrombin but fibrinopeptide A did not impair the esterolytic activity of the enzyme.
J J, Gorman, P A, Castaldi
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Antiplatelet and antithrombin therapy
Coronary Artery Disease, 1994The contemporary pharmacologic treatment of acute myocardial infarction (AMI) includes reperfusion via a thrombolytic agent as well as adjunctive therapy with aspirin and heparin (1). Despite the advances made, current management is limited by the fact that infarct-related artery patency is achieved in only 60–80% of patients at 90 min and Thrombolysis
A, Fernández-Ortiz +2 more
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Pasteurization of antithrombin without generation of the prelatent form of antithrombin
Protein Expression and Purification, 2004Human antithrombin (AT) is the major inhibitor of blood coagulation and has also been shown to exert anti-inflammatory and anti-angiogenic effects. Pasteurization of pharmaceutical AT products is usually performed at 60 degrees C for 10h in the presence of sodium citrate as stabilizer, sometimes in combination with sucrose.
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ANTITHROMBIN IN INFANCY AND CHILDHOOD
Acta Paediatrica, 1975ABSTRACT: Teger‐Nilsson, A‐C. (Department of Clinical Chemistry, Department of Pediatrics, and Department of Blood Coagulation Research, Karolinska sjukhuset, Stockholm). Antithrombin in infancy and childhood. Acta Pediatr Scand, 64:624, 1975.–Anti‐thrombin III was measured immunologically, and antithrombin activity was measured with aid of a new ...
A, Catrine, T, Nilsson
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British Journal of Haematology, 1984
SummaryAntithrombin III (AT‐III) heparin cofactor activity and its antigen levels have been determined in 106 plasma samples from 42 term and preterm neonates. In contrast to healthy adult controls, a reduced activity/antigen (act/ag) ratio (ranging from 0‐26 to 0‐86) was observed in 90% of the samples and was independent of the state of health of the ...
Peters, M. +5 more
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SummaryAntithrombin III (AT‐III) heparin cofactor activity and its antigen levels have been determined in 106 plasma samples from 42 term and preterm neonates. In contrast to healthy adult controls, a reduced activity/antigen (act/ag) ratio (ranging from 0‐26 to 0‐86) was observed in 90% of the samples and was independent of the state of health of the ...
Peters, M. +5 more
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Scandinavian Journal of Urology and Nephrology, 1979
Antithrombin III (AT-III) was measured immunologically in 20 uremic patients on maintenance hemodialysis and in 10 non-dialysed uremic patients. The dialysed patients had slightly elevated AT-III levels. The non-dialysed patients had significantly elevated AT-III levels.
K A, Jørgensen, E, Stoffersen
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Antithrombin III (AT-III) was measured immunologically in 20 uremic patients on maintenance hemodialysis and in 10 non-dialysed uremic patients. The dialysed patients had slightly elevated AT-III levels. The non-dialysed patients had significantly elevated AT-III levels.
K A, Jørgensen, E, Stoffersen
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Circulating antithrombins in pregnancy
BJOG: An International Journal of Obstetrics & Gynaecology, 1982Summary. In a cross‐sectional study circulating levels of antithrombins, antithrombin III1α‐antitrypsin and α2‐macroglobulin were measured in groups of 20 women before pregnancy, during each trimester and post partum. Blood levels of antithrombin III were signicantly lower, α1 antitrypsin higher and %aL2‐macroglobulin no different when compared with ...
B, Teisner, M W, Davey, J G, Grudzinskas
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Archives of Surgery, 1979
To the Editor .—The white clot syndrome recently reported by Towne et al 1 is disturbing. The complications of therapy with heparin are a problem not only for physician and patient, but for the clinical pharmacist, who is often called on to explain them.
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To the Editor .—The white clot syndrome recently reported by Towne et al 1 is disturbing. The complications of therapy with heparin are a problem not only for physician and patient, but for the clinical pharmacist, who is often called on to explain them.
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Hematology/Oncology Clinics of North America, 1992
The general characteristics of antithrombin III (AT III) concentrates available in the United States are described in this article. The effectiveness of AT III concentrates in the prevention and treatment of thrombotic episodes in patients with hereditary AT III deficiency are summarized, and the use of this product in various conditions with acquired ...
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The general characteristics of antithrombin III (AT III) concentrates available in the United States are described in this article. The effectiveness of AT III concentrates in the prevention and treatment of thrombotic episodes in patients with hereditary AT III deficiency are summarized, and the use of this product in various conditions with acquired ...
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