Results 21 to 30 of about 37,585 (155)

Nationwide survey on the use of eltrombopag in patients with severe aplastic anemia: a report on behalf of the French Reference Center for Aplastic Anemia

Haematologica, 2018
Few therapeutic options are available for patients with aplastic anemia who are ineligible for transplantation or refractory to immunosuppressive therapy. Eltrombopag was recently shown to produce trilineage responses in refractory patients. However, the
Etienne Lengline, Bernard Drenou, Pierre Peterlin, Olivier Tournilhac, Julie Abraham, Ana Berceanu, Brigitte Dupriez, Gaelle Guillerm, Emmanuel Raffoux, Flore Sicre de Fontbrune, Lionel Ades, Marie Balsat, Driss Chaoui, Paul Coppo, Selim Corm, Thierry Leblanc, Natacha Maillard, Louis Terriou, Gerard Socié, Regis Peffault de Latour   +19 more
doaj   +1 more source

Basiliximab vs. Antithymocyte Globulin as Initial Induction Therapy for Lung Transplantation: A National Two Years Review

Transplantology, 2022
Basiliximab (BAS) is an interleukin-2 monoclonal antibody initially used as induction therapy after liver and kidney transplantation. BAS use after lung transplantation (LTx) has supplanted antithymocyte globulin (ATG) as the main induction ...
Bruno Mendes, Carlos Figueiredo, Mariana Cabral, Alexandra Borba, Alexandra Mineiro, João Cardoso, Paulo Calvinho, Luísa Semedo, José Fragata   +8 more
doaj   +1 more source

Clinical impact of human Jurkat T-cell-line-derived antithymocyte globulin in multiple myeloma patients undergoing allogeneic stem cell transplantation

Haematologica, 2008
Background Antithymocyte globulin or human Jurkat T-cell-line-derived antilymphocyte globulin is used in allogeneic stem cell transplantation to induce in vivo T-cell depletion to facilitate engraftment and lower graft-versus-host disease.
Francis Ayuk, José A. Perez-Simon, Avichai Shimoni, Anna Sureda, Tatjana Zabelina, Rainer Schwerdtfeger, Rodrigo Martino, Herbert Gottfried Sayer, Adrián Alegre, Juan-José Lahuerta, Djordje Atanackovic, Christine Wolschke, Arnon Nagler, Axel R. Zander, Jesús F. San Miguel, Nicolaus Kröger   +15 more
doaj   +1 more source

Hepatotoxicity induced by horse ATG and reversed by rabbit ATG: a case report

Journal of Medical Case Reports, 2007
Background The use of antilymphocyte agents has improved patient and graft survival in hematopoietic stem cell and solid organ transplantation but has been associated with the development of short-term toxicities as well as long-term complications.
Al-Anazi Khalid A, Aljurf Mahmoud D, Al-Sharif Fahad Z, Al-Omar Hamad M, Alami Ahmed, Farooq Fayyaz   +5 more
doaj   +1 more source

Allogeneic peripheral blood stem cell transplantation with anti-thymocyte globulin versus allogeneic bone marrow transplantation without anti-thymocyte globulin

Haematologica, 2020
We compared severe graft-versus-host-disease (GvHD) free and relapse-free survival and other transplantation outcomes of acute myeloid leukemia (AML) patients given bone marrow (BM) without anti-thymocyte globulin (ATG) versus peripheral blood stem cells
Frédéric Baron, Jacques-Emmanue Galimard, Myriam Labopin, Ibrahim Yakoub-Agha, Riitta Niittyvuopio, Nicolaus Kröger, Laimonas Griskevicius, Depei Wu, Edouard Forcade, Carlos Richard, Mahmoud Aljurf, Grzegorz Helbig, Hélène Labussière-Wallet, Mohamad Mohty, Arnon Nagler   +14 more
doaj   +1 more source

The feasibility and applications of non-invasive cardiac output monitoring, thromboelastography and transit-time flow measurement in living-related renal transplantation surgery : results of a prospective pilot observational study [PDF]

, 2014
Introduction: Delayed graft function (DGF) remains a significant and detrimental postoperative phenomenon following living-related renal allograft transplantation, with a published incidence of up to 15%. Early therapeutic vasodilatory interventions have
Imray, C. (Chris), James Barnes, Lam, For T., Caitlin E Imray, Imray, Caitlin E., Christopher HE Imray, Stephen J Goodyear, Tan, Lam C., Goodyear, Stephen J., Robert Higgins, Barnes, James, Lam C Tan, Kashi, S, For T Lam, S Kashi, Higgins, Rob   +15 more
core   +1 more source

Graft-versus-host disease after allogeneic hematopoietic stem cell transplantation in children

Медицинский совет, 2016
Up to 60 thousand hematopoietic stem cell transplantations (HSCT) are carried out globally all over the world. The outcome of HSCT is largely determined by the probability and severity of the graft-versus-host reaction/disease (GVHD).
Y. V. Skvortsova, D. N. Balashov, V. M. Delyagin   +2 more
doaj   +1 more source

Rabbit Allergy and Kidney Transplant: What’s the connection?

Graduate Medical Education Research Journal, 2023
Mentor: Scott Westphal Program: Internal Medicine Type: Case Report Background: An anti-thymocyte globulin (ATG, Thymoglobulin®) is a polyclonal, anti-human thymocyte antibody derived from rabbits, used for lymphocyte depleting induction ...
Debra Wekesa, Scott Westphal, Eric Langewisch   +2 more
doaj   +1 more source

Evolution of Immune Checkpoint Blockade–Induced Myocarditis Over 2 Years

JACC: Case Reports, 2020
Ipilimumab and nivolumab for melanoma induced smoldering myocarditis remitting with steroids. Rechallenge with nivolumab produced steroid-refractory myocarditis confirmed by electron microscopy.
Timothy G. Norwood, Carrie A. Lenneman, MD, Brian C. Westbrook, Silvio H. Litovsky, MD, Svetlana B. McKee, RN, BSN, Robert M. Conry, MD   +5 more
doaj   +1 more source

Thyroxine-binding globulin: investigation of microheterogeneity [PDF]

, 1981
Preparations of T4-binding globulin (TBG) from human serum was performed using only two affinity chromatography steps. Purity of the protein was demonstrated by a single band in overloaded disc and sodium dodecyl sulfate electrophoresis, equimolar ...
Gärtner, Roland, Horn, K., Henze, R., Pickardt, C. R., Scriba, Peter Christian   +4 more
core   +1 more source