The vapB-vapC operon of Acidovorax citrulli functions as a bona-fide toxin-antitoxin module
Frontiers in Microbiology, 2016 Toxin–antitoxin systems are commonly found on plasmids and chromosomes of bacteria and archaea. These systems appear as biscystronic genes encoding a stable toxin and a labile antitoxin, which protects the cells from the toxin’s activity. Under specific,
Reut eShavit +4 more
doaj +1 more source
Escherichia coli EHEC Germany outbreak preliminary functional annotation using BG7 system [PDF]
, 2011 We have annotated the European outbreak E. coli EHEC genome sequenced by BGI (6-2-2011) and assembled with MIRA by Nick Loman (6-2-2011 ). Our system BG7, Bacterial Genome annotation of Era7 Bioinformatics, predicts ORFs and annotates them based on ...
Eduardo Pareja +4 more
core +2 more sources
Targeting Type II Toxin–Antitoxin Systems as Antibacterial Strategies
Toxins, 2020 The identification of novel targets for antimicrobial agents is crucial for combating infectious diseases caused by evolving bacterial pathogens. Components of bacterial toxin–antitoxin (TA) systems have been recognized as promising therapeutic targets ...
M. Równicki +3 more
semanticscholar +1 more source
Environmental Microbiology Reports, Volume 17, Issue 6, December 2025.A transposon insertion sequencing approach revealed that the novel phage ΦXhv‐1 targets Xanthomonas hortorum pv. vitians through LPS O‐antigen recognition. Mutations in LPS conferring phage resistance reduce bacterial motility and virulence, highlighting a trade‐off that may naturally constrain resistance development and support the sustainable phage ...
Anaelle Baud +7 more
wiley +1 more source
Genomic Evolution of Two Acinetobacter baumannii Clinical Strains from ST-2 Clones Isolated in 2000 and 2010 (ST-2_clon_2000 and ST-2_clon_2010) [PDF]
, 2016 Acinetobacter baumannii is a successful nosocomial pathogen due to its ability to persist in hospital environments by acquiring mobile elements such as transposons, plasmids, and phages. In this study, we compared two genomes of A.
Blasco, L. +8 more
core
Immunological Characterization and Neutralizing Ability of Monoclonal Antibodies Directed Against Botulinum Neurotoxin Type H. [PDF]
, 2016 BackgroundOnly Clostridium botulinum strain IBCA10-7060 produces the recently described novel botulinum neurotoxin type H (BoNT/H). BoNT/H (N-terminal two-thirds most homologous to BoNT/F and C-terminal one-third most homologous to BoNT/A) requires ...
Arnon, Stephen S +5 more
core +1 more source
Antitoxin as a Prophylactic [PDF]
The Boston Medical and Surgical Journal, 1897 n ...
openaire +2 more sources
Prophage encoding toxin/antitoxin system PfiT/PfiA inhibits Pf4 production in Pseudomonas aeruginosa
Microbial Biotechnology, 2020 Pf prophages are ssDNA filamentous prophages that are prevalent among various Pseudomonas aeruginosa strains. The genomes of Pf prophages contain not only core genes encoding functions involved in phage replication, structure and assembly but also ...
Yangmei Li +5 more
semanticscholar +1 more source
Rational Design of Platinum‐Based Confined Electrocatalysts for Oxygen Reduction Reaction
Carbon Neutralization, Volume 4, Issue 6, November 2025.In this review, we highly emphasize effective strategies for the rational design of Pt‐based confined electrocatalysts (PCECs) for oxygen reduction reaction (ORR), which aims to promote the development of efficient ORR electrocatalysts in sustainable energy conversion techniques.
Kechuang Wan +8 more
wiley +1 more source