Results 101 to 110 of about 32,139 (221)

Wound botulism caused by Clostridium subterminale after a heroin injection

open access: yesInfectious Disease Reports, 2018
Botulism is caused by toxin production from many species of Clostridium, most commonly Clostridium botulinum as well as C. baratii and C. butyricum. Development of wound botulism is associated with injection drug users but has also been described in ...
Paris A. Cook   +3 more
doaj   +1 more source

The Sole Mycobacterium smegmatis MazF Toxin Targets tRNALys to Impart Highly Selective, Codon-Dependent Proteome Reprogramming

open access: yesFrontiers in Genetics, 2020
Survival of mycobacteria, both free-living and host-dependent pathogenic species, is dependent on their ability to evade being killed by the stresses they routinely encounter.
Valdir Cristovao Barth   +2 more
doaj   +1 more source

Mono- and multidomain defense toxins of the RelE/ParE superfamily

open access: yesmBio
Toxin–antitoxin (TA) modules are widely distributed across prokaryotes, often existing in large numbers despite their associated fitness costs. Most type II TA modules are bicistronic operons encoding a monodomain toxin and its cognate protein antitoxin.
Kenn Gerdes
doaj   +1 more source

Development and evaluation of candidate subunit vaccine and novel antitoxin against botulinum neurotoxin serotype E

open access: yesHuman Vaccines & Immunotherapeutics, 2020
Botulinum neurotoxins (BoNTs) are among the most toxic proteins. Vaccination is an effective strategy to prevent botulism. To generate a vaccine suitable for human use, a recombinant non-His-tagged isoform of the Hc domain of botulinum neurotoxin ...
Dan-Yang Shi   +9 more
doaj   +1 more source

Type II Toxin-Antitoxin Systems in Escherichia coli [PDF]

open access: yes
He Zhang,1 Shuan Tao,2 Huimin Chen,2 Yewei Fang,2 Yao Xu,3 A-Xiang Han,2 Fang Ma,1,* Wei Liang2,* 1Department of Medical Laboratory, Bengbu Medical University, Bengbu, Anhui, People’s Republic of China; 2Department of Clinical Laboratory, The ...
Fang Y   +7 more
core  

Phages carry orphan antitoxin-like enzymes to neutralize the DarTG1 toxin-antitoxin defense system [PDF]

open access: yes
The astounding number of anti-phage defenses encoded by bacteria is countered by an elaborate set of phage counter-defenses, though their evolutionary origins are often unknown. Here, we report the discovery of an orphan antitoxin counter-defense element
Johannesman, Anna   +3 more
core   +1 more source

Clinical Recovery and Circulating Botulinum Toxin Type F in Adult Patient

open access: yesEmerging Infectious Diseases, 2009
A 56-year-old woman in Helena, Montana, USA, who showed clinical signs of paralysis, received antitoxins to botulinum toxins A, B, and E within 24 hours; nevertheless, symptoms progressed to complete quadriplegia. On day 8, she began moving spontaneously,
Jeremy Sobel   +5 more
doaj   +1 more source

A cis-acting antitoxin domain within the chromosomal toxin–antitoxin module EzeT of Escherichia coli quenches toxin activity

open access: yes, 2015
Toxin-antitoxin (TA) systems are widespread genetic modules in the genomes of bacteria and archaea emerging as key players that modulate bacterial physiology.
Rocker, A., Meinhart, A.
core   +1 more source

Antitoxin.

open access: yesThe Journal of comparative medicine and veterinary archives
Citation: 'antitoxin' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.12901 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
  +9 more sources

Expression, Purification, and Functional Analysis of Novel RelE Operon from X. nematophila

open access: yesThe Scientific World Journal, 2014
Bacterial toxin-antitoxin (TA) complexes induce programmed cell death and also function to relieve cell from stress by various response mechanisms. Escherichia coli RelB-RelE TA complex consists of a RelE toxin functionally counteracted by RelB antitoxin.
Jitendra Singh Rathore   +1 more
doaj   +1 more source

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