Results 81 to 90 of about 32,139 (221)

The Biology and Biochemistry of PhoH2 proteins [PDF]

, 2013
PhoH2 proteins are found in a diverse range of organisms. To date little is known about these proteins and the role they play in the organisms in which they reside.
Andrews, Emma Sophie Vout
core  

Reassessing the Role of the Type II MqsRA Toxin-Antitoxin System in Stress Response and Biofilm Formation: mqsA Is Transcriptionally Uncoupled from mqsR

mBio, 2019
Toxin-antitoxin (TA) systems are broadly distributed modules whose biological roles remain mostly unknown. The mqsRA system is a noncanonical TA system in which the toxin and antitoxins genes are organized in operon but with the particularity that the ...
Nathan Fraikin, Clothilde J. Rousseau, Nathalie Goeders, Laurence Van Melderen   +3 more
doaj   +1 more source

Intrinsic Disorder as a New Frontier in Antimicrobial Resistance and Bacterial Fitness

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
The works examines the link between intrinsic disorder in bacterial protein structure, and bacterial function, and antimicrobial resistance. It highlights how flexible, disordered proteins support secretion, stress responses, desiccation protection, and virulence, while also suggesting that these adaptable regions may provide novel targets for ...
Jack O' Callaghan, Michael P. Ryan, Sarah Hudson, Damien Thompson   +3 more
wiley   +1 more source

Antitoxin degradation scan

, 2018
Data from antitoxin degradation scan simulations used in Figure ...
Bandyopadhyay, Arnab, Ray, J. Christian J., Arnab Bandyopadhyay (5675015), J. Christian J. Ray (188202)   +3 more
core   +1 more source

Human versus equine intramuscular antitoxin, with or without human intrathecal antitoxin, for the treatment of adults with tetanus: a 2x2 factorial randomized control trial [PDF]

, 2022
Background: Intramuscular antitoxin is recommended in tetanus treatment, but there are few data comparing human and equine preparations. As tetanus toxin acts within the central nervous system, where there is limited penetration of peripherally ...
Nguyen, Nguyen Thanh, Bich Hanh, Bui Thi, Tan Thanh, Tran, Vinh Chau, Nguyen Van, Yen, Lam Minh, Hong, Duc Du, Thuy, Duong Bich, Nguyet Oanh, Pham Kieu, Duong, Ha Thi Hai, Wyncoll, Duncan, Thi Tuyen, Pham, Thi Lieu, Pham, Turner, Hugo, Thwaites, C Louise, Quoc Khanh, Phan Nguyen, Van Tan, Le, Thwaites, Guy E, Phuong Dung, Nguyen Thi, Day, Nicholas PJ, Geskus, Ronald B, Loan, Huynh Thi, Vinh Tho, Phan, Hoan Phu, Nguyen, Trung Nghia, Ho Dang, Kestelyn, Evelyne, van Doorn, H Rogier, Diem Thuy, Tran Thi, Van Hao, Nguyen, Huy Nhat, Phung Tran, Thanh Phong, Nguyen   +29 more
core  

Single Tri-Epitopic Antibodies (TeAbs) to Botulinum Neurotoxin Serotypes B, E, and F Recapitulate the Full Potency of a Combination of Three Monoclonal Antibodies in Toxin Neutralization

Toxins
Recombinant monoclonal antibody (mAb) botulinum neurotoxin (BoNT) antitoxins, consisting of three mAbs that bind non-overlapping epitopes, are highly potent. However, the three-mAb mixtures pose unique development and manufacturing challenges.
Jianlong Lou, Wei Hua Wen, Fraser Conrad, Christina C. Tam, Consuelo Garcia-Rodriguez, Shauna Farr-Jones, James D. Marks   +6 more
doaj   +1 more source

Asking the 5 W's for designing next‐generation bioprocessing

AIChE Journal, Volume 72, Issue 9, September 2026.
Abstract Biotechnology is expanding beyond traditional, centralized fermentation and toward next‐generation bioprocessing paradigms that emphasize flexible deployment outside the laboratory with application‐specific performance. However, many bioprocesses fail to translate beyond proof‐of‐concept into industrially viable systems because early design ...
Sangdo Yook, Karoline Maria Vieira Nogueira, Raj Sukumar, Jenna Miller, Hal S. Alper   +4 more
wiley   +1 more source

Genomic Insights Into the Multimetal Resilience and Biofilm‐Templated Nanorod Biosynthesis of Stenotrophomonas bentonitica BII‐R7: Bioremediation and Green Nanotechnology Implications

Microbial Biotechnology, Volume 19, Issue 9, September 2026.
Biofilm extracellular polymeric substances (EPS) in Stenotrophomonas bentonitica BII‐R7 direct the formation of crystalline trigonal selenium nanorods. Comparative genomics identifies a unique genetic toolkit underpinning EPS composition and metal resilience, positioning this strain as a platform for bioremediation and green nanomaterial synthesis ...
Eduardo Perez‐Muelas, Miguel Angel Ruiz‐Fresneda, Guillermo Lazuen‐Lopez, Tatiana Lopez‐Perez, Fouad Eddaoudi‐Lakraichi, Mohammed Bakkali, Mohamed Larbi Merroun   +6 more
wiley   +1 more source

Protective and Pathogenic Antibodies to Citrullinated Antigens

Immunological Reviews, Volume 342, Issue 1, September 2026.
ABSTRACT Autoimmune diseases start years before clinical onset. In rheumatoid arthritis (RA), autoantibodies to citrullinated proteins (ACPA) and to modified IgG (rheumatoid factors, RF) can be detected many years before the inflammatory attack on cartilaginous joints. It has been assumed that these antibodies are pathogenic.
Outi Sareila, Yibo He, Zhongwei Xu, Changrong Ge, Erik Lönnblom, Rikard Holmdahl   +5 more
wiley   +1 more source

Investigation of activity of acinetobacter baumannii toxin-antitoxin system antitoxin. [PDF]

, 2016
Investigation of Activity of Acinetobacter baumannii Toxin-antitoxin System Antitoxin Acinetobacter baumannii is a gram negative opportunistic pathogen which causes variety of nosocomial infections.
Čepauskas, Albinas,
core