Results 1 to 10 of about 46,671 (223)
Historical Perspectives and Guidelines for Botulinum Neurotoxin Subtype Nomenclature [PDF]
Toxins, 2017 Botulinum neurotoxins are diverse proteins. They are currently represented by at least seven serotypes and more than 40 subtypes. New clostridial strains that produce novel neurotoxin variants are being identified with increasing frequency, which ...
Luca Bano +2 more
exaly +4 more sources
Surface Acoustic Wave Immunosensor for Detection of Botulinum Neurotoxin
Sensors, 2023 A Love-type acoustic wave sensor (AT-cut quartz substrate, SiO2 guiding layer) with a center frequency of approximately 120 MHz was used to detect a simulant of pathogenic botulinum neurotoxin type A—recombinant of BoNT-A light chain—in liquid samples ...
Michał Grabka +2 more
doaj +2 more sources
Botulinum and Tetanus Neurotoxins
Annual Review of Biochemistry, 2019 Botulinum neurotoxins (BoNTs) and tetanus neurotoxin (TeNT) are the most potent toxins known and cause botulism and tetanus, respectively. BoNTs are also widely utilized as therapeutic toxins. They contain three functional domains responsible for receptor-binding, membrane translocation, and proteolytic cleavage of host proteins required for synaptic ...
Min Dong +2 more
exaly +4 more sources
Toxins, 2021 Parkinson’s disease is the most common age-related motoric neurodegenerative disease. In addition to the cardinal motor symptoms of tremor, rigidity, bradykinesia, and postural instability, there are numerous non-motor symptoms as well.
Steven D. Mitchell +1 more
doaj +2 more sources
Toxins, 2021 Intradermal injection of botulinum neurotoxin is a frequently performed procedure in aesthetic dermatology to improve facial skin tone, texture, fine wrinkles, and enlarged pores.
Nark-Kyoung Rho, Young-Chun Gil
doaj +1 more source
On Botulinum Neurotoxin Variability [PDF]
mBio, 2015 ABSTRACT The rapidly growing number of botulinum neurotoxin sequences poses the problem of the possible evolutionary significance of the variability of these superpotent neurotoxins for toxin-producing Clostridium species. To progress in the understanding of this remarkable phenomenon, we suggest that researchers should (i) abandon an anthropocentric ...
MONTECUCCO, CESARE +1 more
openaire +4 more sources
Toxins, 2022 The platysma muscle is a thin superficial muscle that covers the entire neck and lower part of the face. The platysma muscle is the primary target muscle for botulinum neurotoxin injection therapy aimed at treating platysmal band and lower facial lifting.
Kyu-Ho Yi +5 more
doaj +1 more source
Toxins, 2020 The neurotoxin formed by Clostridium botulinum Group II is a major cause of foodborne botulism, a deadly intoxication. This study aims to understand the genetic diversity and spread of C. botulinum Group II strains and their neurotoxin genes.
Jason Brunt +5 more
doaj +1 more source
Toxins, 2020 Clostridium botulinum Group I and Clostridium sporogenes are closely related bacteria responsible for foodborne, infant and wound botulism. A comparative genomic study with 556 highly diverse strains of C. botulinum Group I and C.
Jason Brunt +7 more
doaj +1 more source
Adult Intestinal Toxemia Botulism
Toxins, 2020 Intoxication with botulinum neurotoxin can occur through various routes. Foodborne botulism results after consumption of food in which botulinum neurotoxin-producing clostridia (i.e., Clostridium botulinum or strains of Clostridium butyricum type E or ...
Richard A. Harris +2 more
doaj +1 more source