Results 41 to 50 of about 116,934 (269)

Botulinum toxin-A for the treatment of overactive bladder: UK contributions [PDF]

open access: yes, 2013
Background: Botulinum toxin-A (BoNT/A) is now established second-line management for refractory overactivebladder (OAB) and recognised in many incontinence guidelines and pathways.
Fowler, CJ   +13 more
core   +1 more source

Centrally mediated late motor recovery after botulinum toxin injection: Case reports and a review of current evidence

open access: yesJournal of Rehabilitation Medicine, 2017
Objective: Botulinum neurotoxin is commonly utilized in neurorehabilitation as a treatment for focal spasticity. Clinical experience has yielded observations of late motor recovery after intramuscular injection of botulinum neurotoxin, that are not ...
Manuel F. Mas   +2 more
doaj   +1 more source

The light chain but not the heavy chain of botulinum A toxin inhibits exocytosis from permeabilized adrenal chromaffin cells [PDF]

open access: yes, 1989
The heavy and light chains of botulinum A toxin were separated by anion exchange chromatography. Their intracellular actions were studied using bovine adrenal chromaffin cells permeabilized with streptolysin O.
M. Gratzl   +10 more
core   +1 more source

An Integrated Pharmacophore/Docking/3D-QSAR Approach to Screening a Large Library of Products in Search of Future Botulinum Neurotoxin A Inhibitors

open access: yesInternational Journal of Molecular Sciences, 2020
Botulinum toxins are neurotoxins produced by Clostridium botulinum. This toxin can be lethal for humans as a cause of botulism; however, in small doses, the same toxin is used to treat different conditions. Even if the therapeutic doses are effective and
Davide Gentile   +6 more
semanticscholar   +1 more source

Anatomical guide for botulinum neurotoxin injection: Application to cosmetic shoulder contouring, pain syndromes, and cervical dystonia

open access: yesClinical anatomy (New York, N.Y. Print), 2020
This study proposes an ideal botulinum toxin injection point of the trapezius muscle for shoulder line contouring, pain management, and functional impairment.
Kyu-Ho Yi   +5 more
semanticscholar   +1 more source

Guidelines for botulinum neurotoxin injections in piriformis syndrome

open access: yesClinical anatomy (New York, N.Y. Print), 2020
The piriformis muscle is normally involved in piriformis syndrome and can be treated with botulinum neurotoxin using several different injection methods. However, definitive injection guidelines for the muscle have not been reported previously.
Kyu-Ho Yi   +6 more
semanticscholar   +1 more source

Peculiar Binding of Botulinum Neurotoxins [PDF]

open access: yesACS Chemical Biology, 2007
Botulinum neurotoxin (BoNT) is a bacterial toxin that causes paralysis. Recent models have suggested that BoNT recognizes and enters nerve endings by interacting with protein receptors and gangliosides, which are glycosphingolipid components of the cell membrane that modulate cell signaling.
ROSSETTO, ORNELLA, MONTECUCCO, CESARE
openaire   +4 more sources

Patient-Reported Side Effects of Intradetrusor Botulinum Toxin Type A for Idiopathic Overactive Bladder Syndrome [PDF]

open access: yes, 2010
Objective: The aim of the study was a prospective assessment of patient-reported side effects in an open-label study after intradetrusor botulinum toxin injections for idiopathic overactive bladder (OAB). Patients and Methods: Botulinum toxin A injection
Mayer, Margit E.   +15 more
core   +1 more source

The Action of Botulinum Toxin A on the Sternocleidomastoid Muscle: An Experimental Study on Rats

open access: yesThe Scientific World Journal, 2022
In this study, we aim to investigate the effective dose of botulinum neurotoxin A that results in paralysis of the sternocleidomastoid muscle for a minimum duration of 28 days in Wistar rats.
Themistoklis Vampertzis   +6 more
doaj   +1 more source

Botulinum Toxin as Preventive Treatment for Migraine: A Randomized Double-Blind Study [PDF]

open access: yes, 2009
Aim: To determine if botulinum toxin type A (BoNT-A) injections can reduce the frequency and severity of migraines. Methods: Patients (n = 127) were randomized to receive placebo or two doses of BoNT-A (Dysport (R)). The primary endpoint was reduction in
Toelle, Thomas   +13 more
core   +1 more source

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