Results 51 to 60 of about 116,934 (269)
Phage lysin that specifically eliminates Clostridium botulinum Group I cells
Scientific Reports, 2020 Clostridium botulinum poses a serious threat to food safety and public health by producing potent neurotoxin during its vegetative growth and causing life-threatening neuroparalysis, botulism.
Zhen Zhang +4 more
doaj +1 more source
Therapeutic applications of botulinum neurotoxins in head and neck disorders
Saudi Dental Journal, 2015 Objective: The aim of this article is to review the mechanism of action, physiological effects, and therapeutic applications of botulinum neurotoxins in the head and neck area.
Ahmad Alshadwi +2 more
doaj +1 more source
Toxins, 2019 The bacterium Clostridium botulinum is the causative agent of botulism—a severe intoxication caused by botulinum neurotoxin (BoNT) and characterized by damage to the nervous system. In an effort to develop novel C.
S. A. Godakova +10 more
semanticscholar +1 more source
PLoS ONE, 2013 Sanger and shotgun sequencing of Clostridium botulinum strain Af84 type Af and its botulinum neurotoxin gene (bont) clusters identified the presence of three bont gene clusters rather than the expected two. The three toxin gene clusters consisted of bont
Nir Dover +6 more
doaj +1 more source
A Photoactivatable Botulinum Neurotoxin for Inducible Control of Neurotransmission
Neuron, 2019 SUMMARY Regulated secretion is critical for diverse biological processes ranging from immune and endocrine signaling to synaptic transmission. Botulinum and tetanus neurotoxins, which specifically proteolyze vesicle fusion proteins involved in regulated ...
Qi Liu +12 more
semanticscholar +1 more source
Regional and developmental brain expression patterns of SNAP25 splice variants [PDF]
, 2011 SNAP25 is an essential SNARE protein for regulated exocytosis in neuronal cells. Differential splicing of the SNAP25 gene results in the expression of two transcripts, SNAP25a and SNAP25b.
Chamberlain, Luke H. +7 more
core +1 more source
Microbial communities and functional diversity in seafood
JSFA reports, EarlyView.Abstract Functional diversity encompasses ecosystem processes that enhance adaptability to environmental change. This study explores the diversity of microorganisms associated with seafood. In this paper, we present our knowledge of microbial diversity in relation to seafood.
Christian Larbi Ayisi +3 more
wiley +1 more source
A Targeted Therapeutic Rescues Botulinum Toxin-A Poisoned Neurons [PDF]
, 2008 Botulinum neurotoxin (BoNT), a Category A biothreat agent, is the most potent poison known to mankind. Currently no antidote is available to rescue poisoned synapses.
Radharaman Ray +6 more
core
Toxins, 2021 Breast reconstruction after mastectomy is commonly performed using transverse rectus abdominis myocutaneous (TRAM) flap. Previous studies have demonstrated that botulinum neurotoxin injections in TRAM flap surgeries lower the risk of necrosis and allow ...
Kyu-Ho Yi +4 more
doaj +1 more source
Science Advances, 2019 We report the preclinical characterization of two engineered botulinum neurotoxin serotype B proteins with significant therapeutic potential. Although botulinum neurotoxin serotype A (BoNT/A) products are common treatments for various disorders, there is
Mark Elliott +18 more
semanticscholar +1 more source