Results 51 to 60 of about 4,333 (186)

The light chain of tetanus toxin inhibits calcium-dependent vasopressin release from permeabilized nerve endings [PDF]

, 1992
The effects of tetanus toxin and its light and heavy chain subunits on vasopressin release were investigated in digitonin-permeabilized neurosecretory nerve terminals isolated from the neural lobe of the rat pituitary gland.
Weller, U., Nordmann, J. J., Dayanithi, G., Ahnert-Hilger, G., Lnk, H., Gratzl, Manfred   +5 more
core   +1 more source

The Role of Botulinum Neurotoxin A in the Conservative Treatment of Fractures: An Experimental Study on Rats

The Scientific World Journal
This paper explores the role of botulinum neurotoxin in aiding fracture recovery through temporary muscle paralysis. Specifically, it investigates the effects of botulinum neurotoxin-induced paralysis of the sternocleidomastoid muscle on clavicle ...
Themistoklis Vampertzis, Christina Barmpagianni, Chryssa Bekiari, Georgia D. Brellou, Ioannis A. Zervos, Eleftherios Tsiridis, Nikiforos Galanis   +6 more
doaj   +1 more source

Aptamer-based electrochemical biosensor for Botulinum neurotoxin [PDF]

, 2009
We have developed an aptamer-based electrochemical sensor for detection of Botulinum neurotoxin, where steric hindrance is applied to achieve specific signal amplification via conformational change of the aptamer.
Fang Wei, Wei, Fang, Ho, Chih-Ming, Chih-Ming Ho   +3 more
core   +1 more source

Orofacial Drinking Tremor: A Case Series and Literature Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Task‐specific orofacial tremor is a rare condition in which rhythmic oscillations of orofacial muscles occur during specific actions. Drinking tremor represents a recurrent pattern in isolated reports, although its phenomenology and underlying mechanisms remain incompletely defined.
Daniele Birreci, Luca Angelini, Simone Aloisio, Anna S. Grandolfo, Sara Cirinei, Adriana Martini, Martina De Riggi, Matteo Bologna   +7 more
wiley   +1 more source

Uso da toxina botulínica no controle do bruxismo [PDF]

, 2014
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências da Saúde. Odontologia.A toxina botulínica é uma substância produzida pela bactéria Clostridium botulinum, e o seu uso oferece ao cirurgião dentista uma nova alternativa para ...
Francescon, Ariane
core  

Applications, impacts and consequences of botulinum toxin usage in medicine

Journal of Education, Health and Sport
Introduction Botulinum toxin is a neurotoxin produced by the gram-positive bacteria Clostridium botulinum. Botulinum toxin has found great interest in the field of aesthetic medicine, but it has many other applications in other areas of medicine.  
Weronika Kiełt, Julia Kozłowska, Gabriela Broniec, Barbara Wajdowicz, Aleksandra Kudła, Rozalia Czapiewska, Aleksandra Dziewulska, Aleksandra Wróbel, Laura Pacek, Klaudia Kowalska   +9 more
doaj   +1 more source

Independent evolution of neurotoxin and flagellar genetic loci in proteolytic Clostridium botulinum

BMC Genomics, 2009
Background Proteolytic Clostridium botulinum is the causative agent of botulism, a severe neuroparalytic illness. Given the severity of botulism, surprisingly little is known of the population structure, biology, phylogeny or evolution of C.
Twine Susan M, Mason David R, Paul Catherine J, Carter Andrew T, Alston Mark J, Logan Susan M, Austin John W, Peck Michael W   +7 more
doaj   +1 more source

Synaptotagmin Binding to Botulinum Neurotoxins

Biochemistry, 2019
Botulinum neurotoxins (BoNTs) are exceptionally toxic proteins that cause paralysis but are also extensively used as treatment for various medical conditions. Most BoNTs bind two receptors on neuronal cells, namely, a ganglioside and a protein receptor.
Markel Martínez-Carranza, Pilar Blasco, Robert Gustafsson, Min Dong, Ronnie Per-Arne Berntsson, Göran Widmalm, Pål Stenmark   +6 more
openaire   +4 more sources

Structure of dual receptor binding to botulinum neurotoxin B [PDF]

, 2014
Botulinum neurotoxins are highly toxic, and bind two receptors to achieve their high affinity and specificity for neurons. Here we present the first structure of a botulinum neurotoxin bound to both its receptors.
Peng, Lisheng, Dong, Min, Stenmark, Pål, Berntsson, Ronnie P-A   +3 more
core   +1 more source

Histopathological changes of the buccal mucosa and skin after botulinum neurotoxin intramuscular injection in rats (immunohistochemical study)

BMC Oral Health
Background A surplus of clinical studies focused mainly on the clinical impacts of botulinum neurotoxin type A disregarding the histopathological changes stemming from its injection.
Gihan S. Hassan, Basant H. Abouzaid, Reda G. Saleh   +2 more
doaj   +1 more source