Results 61 to 70 of about 116,934 (269)

Pitch Strength & Percent Vocal Creak to Assess Treatment Response in Adductor Laryngeal Dystonia

The Laryngoscope, EarlyView.
Pitch Strength (PS) and Percent Vocal Creak (%VC) were measured before and after botulinum neurotoxin treatment in patients with adductor laryngeal dystonia (AdLD). While PS and %VC correlated with changes in disruption frequency and perceptual severity, they did not demonstrate robust group‐level treatment sensitivity.
Jesse D. Hoffmeister, Maisie K. Simpson, Joseph Hayek, Scott Lunos, Stephanie Misono, Jürgen Konczak   +5 more
wiley   +1 more source

Capsaicin protects neuromuscular junctions from the inhibitory effects of botulinum neurotoxin A [PDF]

, 2008
Within 24 hrs after injecting botulinum neurotoxin A (BoNT/A) into the hindlimb, mice lost the toe spread reflex and developed progressive muscle weakness. At the same time, the compound muscle action potential amplitude decreased. Injection of capsaicin
Carmen Garcia, Joseph McArdle, Kormakur Hognason, Joseph Potian, Baskaran Thyagarajan, Natalia Krivitskaya   +5 more
core  

Role of Diagnostic Nerve Blocks in the Goal-Oriented Treatment of Spasticity with Botulinum Toxin Type A: A Case–Control Study

Toxins
The goal-setting process is pivotal in managing patients with disabling spasticity. This case–control study assessed the role of diagnostic nerve blocks in guiding the goal-setting process within goal-targeted treatment of spasticity with botulinum ...
Mirko Filippetti, Stefano Tamburin, Rita Di Censo, Martina Adamo, Elisa Manera, Jessica Ingrà, Elisa Mantovani, Salvatore Facciorusso, Marco Battaglia, Alessio Baricich, Andrea Santamato, Nicola Smania, Alessandro Picelli   +12 more
doaj   +1 more source

Noradrenaline release from permeabilized synaptosomes is inhibited by the light chain of tetanus toxin [PDF]

, 1992
Noradrenaline release from rat brain cortical synaptosomes permeabilized with streptolysin O can be triggered by μM concentrations of free Ca2+. This process was inhibited within minutes by tetanus toxin and its isolated light chain, but not by its heavy
Stecher, Brigitte, Weller, U., De Graan, P., Gratzl, Manfred, Graan, P.N.E. de, Gratz, M., Hens, Jacques J.H., Stecher, B., Gispen, W. H., De Graan, Pierre N.E., Hens, J.J.H., Hens, J., Jacques J.H. Hens, Ulrich Weller, Willem-Hendrik Gispen, Pierre N.E. De Graan, Manfred Gratzl, Gispen, Willem-Hendrik, Gispen, W.H., Weller, Ulrich, Brigitte Stecher   +20 more
core   +2 more sources

Why Are Botulinum Neurotoxin-Producing Bacteria So Diverse and Botulinum Neurotoxins So Toxic?

Toxins, 2019
Botulinum neurotoxins (BoNTs) are the most lethal toxins among all bacterial, animal, plant and chemical poisonous compounds. Although a great effort has been made to understand their mode of action, some questions are still open.
B. Poulain, M. Popoff
semanticscholar   +1 more source

Orofacial Drinking Tremor: A Case Series and Literature Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Task‐specific orofacial tremor is a rare condition in which rhythmic oscillations of orofacial muscles occur during specific actions. Drinking tremor represents a recurrent pattern in isolated reports, although its phenomenology and underlying mechanisms remain incompletely defined.
Daniele Birreci, Luca Angelini, Simone Aloisio, Anna S. Grandolfo, Sara Cirinei, Adriana Martini, Martina De Riggi, Matteo Bologna   +7 more
wiley   +1 more source

Structural Basis of Botulinum Toxin Type F Binding to Glycosylated Human SV2A: In Silico Studies at the Periphery of a Lipid Raft

Biomolecules, 2022
Botulinum neurotoxins are the deadliest microbial neurotoxins in humans, with a lethal dose of 1 ng/kg. Incidentally, these neurotoxins are also widely used for medical and cosmetic purposes.
Fodil Azzaz, Didier Hilaire, Jacques Fantini   +2 more
doaj   +1 more source

Botulinum Neurotoxin Serotypes Detected by Electrochemical Impedance Spectroscopy

Toxins, 2015
Botulinum neurotoxin is one of the deadliest biological toxins known to mankind and is able to cause the debilitating disease botulism. The rapid detection of the different serotypes of botulinum neurotoxin is essential for both diagnosis of botulism and
Alison C. Savage, Nicholas Buckley, Jennifer Halliwell, Christopher Gwenin   +3 more
doaj   +1 more source

Identification of a botulinum neurotoxin-like toxin in a commensal strain of Enterococcus faecium

Cell Host and Microbe, 2018
Summary Botulinum neurotoxins (BoNTs), produced by various Clostridium strains, are a family of potent bacterial toxins and potential bioterrorism agents.
Sicai Zhang, F. Lebreton, Michael J. Mansfield, S. Miyashita, Jie Zhang, Julia A. Schwartzman, Liang Tao, G. Masuyer, Mark Carranza, P. Stenmark, M. Gilmore, A. Doxey, M. Dong   +12 more
semanticscholar   +1 more source

Botulinum Neurotoxin: The Ugly Duckling [PDF]

European Neurology, 2009
This review presents a brief account of the most significant biological effects and clinical applications of botulinum neurotoxins, in a way comprehensive even for casual readers who are not familiar with the subject. The most toxic known substances in botulinum neurotoxins are polypeptides naturally synthesized by bacteria of the genus <i> ...
openaire   +3 more sources