Results 71 to 80 of about 20,701 (223)
Reply to: Deprescribing after DBS in Dystonia: Promise, Pitfalls, and a Path Forward
Movement Disorders Clinical Practice, EarlyView.
Marcela A. Montiel, Alfonso Fasano
wiley +1 more source
Emerging Treatments for Erectile Dysfunction
Trends in Urology &Men's Health, Volume 17, Issue 3, June 2026.ABSTRACT Erectile dysfunction (ED) is a prevalent condition that can significantly affect men's sexual health and quality of life, and for which there are many well‐studied effective treatments. In spite of this, many individuals still seek out alternative therapies.
Resa Magill +3 more
wiley +1 more source
Antiepileptic Effects of Botulinum Neurotoxin E [PDF]
The Journal of Neuroscience, 2005 Experimental studies suggest that the delivery of antiepileptic agents into the seizure focus might be of potential utility for the treatment of focal-onset epilepsies. Botulinum neurotoxin E (BoNT/E) causes a prolonged inhibition of neurotransmitter release after its specific cleavage of the synaptic protein synaptosomal-associated protein of 25 kDa ...
Costantin L +12 more
openaire +7 more sources
Amylase release from streptolysin O-permeabilized pancreatic acinar cells. Effects of Ca2+, guanosine 5'-[gamma-thio]triphosphate, cyclic AMP, tetanus toxin and botulinum A toxin [PDF]
, 1992 The molecular requirements for amylase release and the intracellular effects of botulinum A toxin and tetanus toxin on amylase release were investigated using rat pancreatic acinar cells permeabilized with streptolysin O.
Ahnert-Hilger, G. +4 more
core
Phenol Neurolysis in Pain and Palliative Medicine
Pain Practice, Volume 26, Issue 5, June 2026.ABSTRACT Background Pain is a common symptom in palliative care and affects patients' quality of life considerably. Standard analgesics are sometimes insufficient and are associated with substantial side effects. Neurolysis, the targeted destruction of nerves using thermal or chemical agents, offers an additional option for managing localized pain in ...
Jeroen H. A. Creemers +6 more
wiley +1 more source
Neurological Research and Practice, 2019 Background Selective peripheral denervation via botulinum neurotoxin injections into dystonic muscles is the first-line treatment for cervical dystonia.
Thorsten M. Odorfer +4 more
doaj +1 more source
Cluster of Botulism among dutch tourists in Turkey, june 2008 [PDF]
, 2010 In June 2008, three Dutch tourists participating in a mini-cruise in Turkey needed urgent repatriation for antitoxin treatment because of symptoms of botulism.
Ouwerkerk, M., van +2 more
core +1 more source
A Cell Line for Detection of Botulinum Neurotoxin Type B [PDF]
, 2017 Botulinum neurotoxins (BoNTs) type A and type B are commonly used as biopharmaceutics for neurological diseases, uniquely allowing months-long paralysis of target muscles.
Adler +35 more
core +2 more sources
Repurpose an FDA‐Approved Antibody Using DARPin‐Scaffolded Bridge Protein
Chemistry–Methods, Volume 6, Issue 5, May 2026.The cell line and scalable upstream/downstream process development needed for every new monoclonal antibody are both highly expensive and time‐consuming, significantly increasing the cost of new antibody therapeutics. By contrast, the production of many synthetic binders can be accomplished rapidly and with lower production costs.
Michael Woolley +4 more
wiley +1 more source
Botulinum neurotoxin type C protease induces apoptosis in differentiated human neuroblastoma cells [PDF]
, 2016 Neuroblastomas constitute a major cause of cancer-related deaths in young children. In recent years, a number of translation-inhibiting enzymes have been evaluated for killing neuroblastoma cells. Here we investigated the potential vulnerability of human
Binz, T. +3 more
core +1 more source