Journal of Rehabilitation Medicine, 2017 Objective: Botulinum neurotoxin is commonly utilized in neurorehabilitation as a treatment for focal spasticity. Clinical experience has yielded observations of late motor recovery after intramuscular injection of botulinum neurotoxin, that are not ...
Manuel F. Mas +2 more
doaj +1 more source
Novel Anatomical Proposal for Botulinum Neurotoxin Injection Targeting Lateral Canthal Rhytids
Toxins, 2022 Botulinum neurotoxin injections near the lateral canthal rhytids are commonly used in cosmetic settings; however, there is a lack of thorough anatomical knowledge, and an effective way to treat them with accumulating knowledge is needed.
Kyu-Ho Yi +5 more
doaj +1 more source
The light chain but not the heavy chain of botulinum A toxin inhibits exocytosis from permeabilized adrenal chromaffin cells [PDF]
, 1989 The heavy and light chains of botulinum A toxin were separated by anion exchange chromatography. Their intracellular actions were studied using bovine adrenal chromaffin cells permeabilized with streptolysin O.
M. Gratzl +9 more
core +1 more source
Therapy of Sialorrhea with Botulinum Neurotoxin [PDF]
Neurology and Therapy, 2019 Botulinum neurotoxin (BoNT) is considered the treatment of choice for various symptoms and diseases such as focal dystonia and focal spasticity. The effects of BoNT on the salivary glands have also been known for years, but their use was limited because of a lack of approval studies.
Jost, Wolfgang H. +7 more
openaire +4 more sources
Peculiar Binding of Botulinum Neurotoxins [PDF]
ACS Chemical Biology, 2007 Botulinum neurotoxin (BoNT) is a bacterial toxin that causes paralysis. Recent models have suggested that BoNT recognizes and enters nerve endings by interacting with protein receptors and gangliosides, which are glycosphingolipid components of the cell membrane that modulate cell signaling.
ROSSETTO, ORNELLA, MONTECUCCO, CESARE
openaire +4 more sources
Botulinum toxin-A for the treatment of overactive bladder: UK contributions [PDF]
, 2013 Background: Botulinum toxin-A (BoNT/A) is now established second-line management for refractory overactivebladder (OAB) and recognised in many incontinence guidelines and pathways.
Fowler, CJ +13 more
core +1 more source
The Action of Botulinum Toxin A on the Sternocleidomastoid Muscle: An Experimental Study on Rats
The Scientific World Journal, 2022 In this study, we aim to investigate the effective dose of botulinum neurotoxin A that results in paralysis of the sternocleidomastoid muscle for a minimum duration of 28 days in Wistar rats.
Themistoklis Vampertzis +6 more
doaj +1 more source
Botulinum-Neurotoxin-A induzierte cholinerge Varikositäten im Caudatus-Putamen-Komplex der Maus: eine quantitative Studie [PDF]
, 2018 Nach intrastriataler Injektion von Botulinum-Neurotoxin-A in C57BL/6-Mäuse zeigten sich Botulinum-Neurotoxin-induzierte Varikositäten, kurz BiVs. Es wurden sowohl zeitliche als auch dosisabhängige Veränderungen der Chat-positiven Varikositätenvolumina ...
Spiewok, Juliane (gnd: 1161741976)
core +1 more source
Phage lysin that specifically eliminates Clostridium botulinum Group I cells
Scientific Reports, 2020 Clostridium botulinum poses a serious threat to food safety and public health by producing potent neurotoxin during its vegetative growth and causing life-threatening neuroparalysis, botulism.
Zhen Zhang +4 more
doaj +1 more source
Therapeutic applications of botulinum neurotoxins in head and neck disorders
Saudi Dental Journal, 2015 Objective: The aim of this article is to review the mechanism of action, physiological effects, and therapeutic applications of botulinum neurotoxins in the head and neck area.
Ahmad Alshadwi +2 more
doaj +1 more source