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Therapeutic Use of Botulinum Neurotoxins in Dermatology: Systematic Review [PDF]

open access: yesToxins, 2021
Botulinum toxin is a superfamily of neurotoxins produced by the bacterium Clostridium Botulinum with well-established efficacy and safety profile in focal idiopathic hyperhidrosis.
Emanuela Martina   +4 more
doaj   +2 more sources

Harnessing the Membrane Translocation Properties of AB Toxins for Therapeutic Applications

open access: yesToxins, 2021
Over the last few decades, proteins and peptides have become increasingly more common as FDA-approved drugs, despite their inefficient delivery due to their inability to cross the plasma membrane.
Numa Piot   +2 more
doaj   +3 more sources

Mechanisms of Botulinum Toxin Type A Action on Pain [PDF]

open access: yesToxins, 2019
Already a well-established treatment for different autonomic and movement disorders, the use of botulinum toxin type A (BoNT/A) in pain conditions is now continuously expanding. Currently, the only approved use of BoNT/A in relation to pain is the treatment of chronic migraines. However, controlled clinical studies show promising results in neuropathic
Matak, Ivica   +3 more
openaire   +7 more sources

Botulinum toxin type A versus botulinum toxin type B for cervical dystonia [PDF]

open access: yesCochrane Database of Systematic Reviews, 2016
This is an update of a Cochrane review first published in 2003. Cervical dystonia is the most common form of focal dystonia and is a disabling disorder characterised by painful involuntary head posturing. There are two available formulations of botulinum toxin, with botulinum toxin type A (BtA) usually considered the first line therapy for this ...
Duarte, GS   +7 more
  +9 more sources

An Integrative Approach to Computational Modelling of the Gene Regulatory Network Controlling Clostridium botulinum Type A1 Toxin Production.

open access: yesPLoS Computational Biology, 2016
Clostridium botulinum produces botulinum neurotoxins (BoNTs), highly potent substances responsible for botulism. Currently, mathematical models of C.
Adaoha E C Ihekwaba   +4 more
doaj   +2 more sources

Goal Attainment: A Clinically Meaningful Measure of Success of Botulinum Toxin-A Treatment for Lower Limb Spasticity in Ambulatory Patients

open access: yesArchives of Rehabilitation Research and Clinical Translation, 2021
Objectives: The objectives of this study were to evaluate whether botulinum toxin type A (BoNT-A) treatment for lower limb spasticity leads to patient goal attainment and identify factors associated with positive goal attainment and to assess the effect ...
Subbuh Choudhry, MBBS   +4 more
doaj   +1 more source

The Use of Botulinum Toxin A as an Adjunctive Therapy in the Management of Chronic Musculoskeletal Pain: A Systematic Review with Meta-Analysis

open access: yesToxins, 2021
Several studies have investigated the effect of botulinum toxin A (BoNT-A) for managing chronic musculoskeletal pain, bringing contrasting results to the forefront.
Simone Battista   +7 more
doaj   +1 more source

Lower facial remodeling with botulinum toxin type A for the treatment of masseter hypertrophy [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2014
BACKGROUND: Masseter hypertrophy has been treated with botulinum toxin injections because of esthetic complaints especially in Asians. OBJECTIVES: The goal of the present study was to evaluate the efficacy of abobotulin toxin use in masseter hipertrophy ...
Fernanda Homem de Mello de Souza Klein   +4 more
doaj   +2 more sources

Botulinum Toxin Type A for Treatment of Masseter Hypertrophy: Volumetric Analysis of Masseter Muscle Reduction over Time [PDF]

open access: yesArchives of Aesthetic Plastic Surgery, 2016
Background There has been increasing interest in facial contouring procedures throughout Asian countries. As such, botulinum toxin A injections for masseteric hypertrophy have become a common procedure provided to patients who desire non-surgical ...
Edward Ilho Lee   +4 more
doaj   +1 more source

Evaluation of the botulinum toxin effects in the correction of gummy smile 32 weeks after application

open access: yesABCS Health Sciences, 2022
Introduction: The use of botulinum toxin type A (BTX-A) to correct gummy smile has become popular in recent years. Objective: To evaluate the effects of BTX-A application in the correction of gummy smile 2 and 32 weeks after application.
Carlos Eduardo Alonso Vieira   +7 more
doaj   +1 more source

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