Results 1 to 10 of about 3,233 (250)

Acyclic Cucurbit[n]uril‐Type Molecular Containers Bind Neuromuscular Blocking Agents In Vitro and Reverse Neuromuscular Block In Vivo

Angewandte Chemie - International Edition, 2012
Be my guest: two acyclic cucurbit[n]uril-type receptors that carry SO(3) (-) -groups bind tightly to several commonly used neuromuscular blocking agents, such as rocuronium, in aqueous solution as revealed by direct and competitive UV/Vis binding assays.
Da Ma, Ulrike Hoffmann, Matthias Eikermann   +2 more
exaly   +2 more sources

Effects of neuromuscular blocking agents on central respiratory chemosensitivity in newborn rats

Biological Research, 2005
Neuromuscular blocking agents suppress central respiratory activity through their inhibitory effects on preinspiratory neurons and the synaptic drive from preinspiratory neurons to inspiratory neurons.
SHIGEKI SAKURABA, SHUN-ICHI KUWANA, LARS I ERIKSSON, YASUMASA OKADA, RYOICHI OCHIAI, MASANORI KASHIWAGI, EIKI HATORI, STEN G. E. LINDAHL, JUNZO TAKEDA   +8 more
doaj   +2 more sources

A surgeon′s assessment of inadequate neuromuscular antagonism in a case of prolonged neuromuscular blockade

Journal of Anaesthesiology Clinical Pharmacology, 2013
Evaluation of the degree of neuromuscular blockade by the surgeon using clinical criteria alone is unreliable. We report a case of prolonged neuromuscular blockade lasting 5.5 h, where an additional intra-operative dose of neuromuscular relaxant was ...
James J Lamberg, Joseph F Answine
doaj   +2 more sources

Deep Neuromuscular Blockade During General Anesthesia: Advantages, Challenges, and Future Directions

Anesthesia Research
Background: Neuromuscular blocking agents play an important role in modern anesthesia by facilitating optimal surgical conditions through deep muscle relaxation.
Jacob Rosenberg, Thomas Fuchs-Buder
doaj   +2 more sources

Novel drug development for neuromuscular blockade

Journal of Anaesthesiology Clinical Pharmacology, 2016
Pharmacological advances in anesthesia in recent decades have resulted in safer practice and better outcomes. These advances include improvement in anesthesia drugs with regard to efficacy and safety profiles.
Amit Prabhakar, Alan D Kaye, Melville Q Wyche, Orlando J Salinas, Kenneth Mancuso, Richard D Urman   +5 more
doaj   +2 more sources

Pharmacokinetic studies of neuromuscular blocking agents: Good Clinical Research Practice (GCRP)

Acta Anaesthesiologica Scandinavica, 2000
In September 1997, an international consensus conference on standardization of studies of neuromuscular blocking agents was held in Copenhagen, Denmark.
D Østergaard, F Donati, J P Kampmann
exaly   +1 more source

The influence of new 1,2,3-triazolo-1,4-benzodiazepine derivatives on the muscle tone of rodents

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2023
Anxiety disorders represent one of the most prevalent categories of psychiatric illnesses, affecting individuals regardless of gender, age, or social standing. They result in substantial personal and societal costs.
I. V. Botsula, I. V. Kireyev, O. M. Koshovyi, V. A. Chebanov   +3 more
doaj   +1 more source

Use of Dexmedetomidine as an Adjuvant to Propofol along with Neurophysiological Monitoring of the Seventh Cranial Nerve during Cerebello- Pontine Tumour Excision Surgery [PDF]

Journal of Clinical and Diagnostic Research, 2021
Cerebello‑Pontine Angle (CPA) surgeries are very challenging for neurosurgeons as it lies very close to brain stem so various cranial nerves are at risk of damage. Generally, such surgeries require neuromuscular monitoring of various cranial nerves. For
POOJA ARPAN SHAH, GAYATRI VASAGADEKAR, AKHILESH CHHAYA   +2 more
doaj   +1 more source

Association between neuromuscular blocking agent use and outcomes among out-of-hospital cardiac arrest patients treated with extracorporeal cardiopulmonary resuscitation and target temperature management: A secondary analysis of the SAVE-J II study

Resuscitation Plus, 2023
Background: Neuromuscular blocking agents are used to control shivering in cardiac arrest patients treated with target temperature management. However, their effect on outcomes in patients treated with extracorporeal cardiopulmonary resuscitation is ...
Masatoshi Uchida, Migaku Kikuchi, Yasuo Haruyama, Toru Takiguchi, Toru Hifumi, Akihiko Inoue, Tetsuya Sakamoto, Yasuhiro Kuroda   +7 more
doaj   +1 more source

Do clinical signs of recovery from neuromuscular blockade compare reliably with objective parameters of train-of-four and double burst stimulation: An observational single-center study

The Indian Anaesthetists' Forum, 2020
Background: Recovery from neuromuscular blockade is commonly assessed by clinical signs. There exists wide disparity in what is recommended to monitor neuromuscular blockade and routine clinical practice by anesthesiologists. The objective signs of train-
Bhavna Hooda, Rijesh R Unnithan, Saurabh Sud, Deepak Dwivedi, Puja Dudeja   +4 more
doaj   +1 more source