Laparoscopic fundoplication under general anesthesia in a child with spinal muscular atrophy type II: a case report [PDF]
BMC PediatricsBackground Spinal muscular atrophy (SMA) linked to chromosome 5q demonstrates an autosomal recessive inheritance pattern. SMA is characterized by diffuse, symmetric, proximal muscle weakness, with lower limb predominance in the lower limbs than in the ...
Lufeng Yang, Zugang Yi, Fang Chen
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Pharmacological Characteristics of the Inhibition of Nondepolarizing Neuromuscular Blocking Agents at Human Adult Muscle Nicotinic Acetylcholine Receptor [PDF]
Anesthesiology, 2009 Background Nondepolarizing neuromuscular blocking agents (NMBAs) are classic competitive-inhibitors at the muscle nicotinic acetylcholine receptor (nAChR). Although the fetal subtype muscle nAChR has been extensively studied at a molecular level, less is known about the interaction between nondepolarizing NMBAs and the human ...
Lars I Eriksson
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Narrative Review of the Role of Nondepolarizing Neuromuscular Blocking Agents in Anesthesia: Perspective 2026. [PDF]
Med Sci MonitRadkowski P +6 more
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Archives of Anesthesia and Critical Care, 2022 Background: The utility of Neuromuscular monitoring (NMT) has not been studied in Indian scenario till date. We did a survey to evaluate the knowledge, attitude, practices of NMT among Indian anesthesiologists. Methods: A questionnaire-based google form
Sonal Goyal, Bhavna Gupta
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Association between levobupivacaine and pancuronium. Interference in neuromuscular transmission and blockade in rats [PDF]
Acta Cirúrgica Brasileira, 2016 PURPOSE: To evaluate the effects of levobupivacaine on neuromuscular transmission and neuromuscular blockade produced by pancuronium in vitro. METHODS: Thirty rats were distributed into groups (n = 5) according to the drug used alone or in combination:
Vanessa Henriques Carvalho +5 more
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Neuromuscular blockers and their reversal: have we finally found the on-off switches?
Ain Shams Journal of Anesthesiology, 2021 Background A nondepolarizing neuromuscular blocking agent (NMBA) with a succinylcholine-like quick onset and offset has been the holy grail of the science of neuromuscular blockade.
Shagun Bhatia Shah +3 more
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Chronic exposure to dexamethasone may not affect sugammadex reversal of rocuronium-induced neuromuscular blockade: an in vivo study on rats [PDF]
Anesthesia and Pain Medicine, 2023 Background Chronic glucocorticoid exposure is associated with resistance to nondepolarizing neuromuscular blocking agents. Therefore, we hypothesized that sugammadex-induced recovery would occur more rapidly in subjects exposed to chronic dexamethasone ...
Ha Yeon Park +6 more
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Masseter Muscle Rigidity and Nondepolarizing Neuromuscular Blocking Agents [PDF]
Mayo Clinic Proceedings, 1997 Masseter muscle rigidity has been identified as a possible risk factor for malignant hyperthermia (MH) and is usually noted in children receiving intravenously administered succinylcholine chloride after mask induction with halothane. Nondepolarizing muscle relaxants are considered safe for persons susceptible to MH.
A, Albrecht, D J, Wedel, G A, Gronert
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Effects of adenosine receptor agonist on the rocuroniuminduced neuromuscular block and sugammadex-induced recovery [PDF]
Korean Journal of Anesthesiology, 2018 Background Several types of receptors are found at neuromuscular presynaptic membranes. Presynaptic inhibitory A1 and facilitatory A2A receptors mediate different modulatory functions on acetylcholine release. This study investigated whether adenosine A1
Yong Beom Kim +7 more
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