Interaction of rocuronium with human liver cytochromes P450
Rocuronium is a neuromuscular blocking agent acting as a competitive antagonist of acetylcholine. Results of an inhibition of eight individual liver microsomal cytochromes P450 (CYP) are presented. As the patients are routinely premedicated with diazepam,
Eva Anzenbacherová +2 more
exaly +3 more sources
Rocuronium for Treatment of Sugammadex Anaphylaxis: A Case Report [PDF]
Anaphylaxis presents as a complex and unpredictable intraoperative emergency. Rocuronium is among the most common triggering agents for intraoperative anaphylaxis.
Logan H. Cone +2 more
doaj +2 more sources
Median effective dose of rocuronium for the prevention of succinylcholine-induced fasciculation: an age-stratified study [PDF]
Background Succinylcholine, a commonly used depolarizing neuromuscular blocking relaxant, may produce fasciculation and postoperative myalgia as adverse effects.
Shunping Tian +7 more
doaj +2 more sources
Remifentanil Versus Rocuronium for Optimising Video Laryngoscopy Assisted Tracheal Intubation-The ROCVIDEO Trial Protocol. [PDF]
ABSTRACT Background Routine use of neuromuscular blocking agents (NMBAs) is widely recommended to facilitate tracheal intubation. However, NMBA use is associated with potential adverse effects, including postoperative respiratory complications, intraoperative awareness and anaphylaxis.
Ipsen EØ +19 more
europepmc +2 more sources
A Case of Respiratory Arrest After Lung Cancer Surgery due to Recurarization of Rocuronium Bromide. [PDF]
An 82‐year‐old male lung cancer patient experienced respiratory arrest after surgery due to recurarization of rocuronium bromide. Considering that many lung cancer patients are elderly and have numerous comorbidities, the risk of recurarization associated with muscle relaxants should always be considered.
Miura H, Miura J, Goto S, Yamamoto T.
europepmc +2 more sources
Dilution and slow injection reduces the incidence of rocuronium-induced withdrawal movements in children [PDF]
BackgroundThe aim of this study was to evaluate whether slow injection of diluted rocuronium could reduce rocuronium-induced withdrawal movements effectively in children.MethodsAfter loss of consciousness, rocuronium 0.6 mg/kg was administered into 171 ...
Young Hee Shin +8 more
doaj +1 more source
Anaphylaxis to rocuronium [PDF]
Reports about anaphylactic and anaphylactoid reactions to rocuronium have increased recently. We report two new cases of documented grade III anaphylaxis, leading to death in one patient. The first case occurred in an 81-year-old ASA II woman scheduled for emergency abdominal surgery.
C, Baillard +6 more
openaire +2 more sources
Rocuronium Bromide Inhibits Inflammation and Pain by Suppressing Nitric Oxide Production and Enhancing Prostaglandin E Synthesis in Endothelial Cells [PDF]
Purpose Rocuronium bromide is a nondepolarizing neuromuscular blocking drug and has been used as an adjunct for relaxation or paralysis of the skeletal muscles, facilitation of endotracheal intubation, and improving surgical conditions during general ...
Sang Bin Baek +7 more
doaj +1 more source
Treatment of rocuronium-induced anaphylaxis using sugammadex - A case report - [PDF]
Background Perioperative anaphylaxis is a life-threatening clinical condition characterized by severe respiratory and cardiovascular manifestations. Neuromuscular blocking agents are the most common cause of anaphylaxis during anesthesia.
Sun-Min Kim, Sei-hoon Oh, Seung-Ah Ryu
doaj +1 more source
Pharmacological interventions for acceleration of the onset time of rocuronium: a meta-analysis. [PDF]
Rocuronium is an acceptable alternative when succinylcholine is contraindicated for facilitating the endotracheal intubation. However, the onset time of rocuronium for good intubation condition is still slower than that condition of succinylcholine. This
Jing Dong +4 more
doaj +1 more source

