Results 21 to 30 of about 123 (105)
Myasthenia gravis, a disorder of neuromuscular transmission, presents a unique challenge to the perioperative anesthetic management of morbidly obese patients.
Megana Ballal, Tracey Straker
doaj +1 more source
Background Glycosylation is one of the major posttranslational modifications of proteins and it is essential for proteins to obtain normal biological functions.
Wataru Sakai +3 more
doaj +1 more source
Acute tolerance to rocuronium -A case report- [PDF]
Background A booster dose can result in a similar reaction to the initial dose. Neuromuscular blocking agents (NMBAs) can produce a comparable reaction in the absence of specific pathophysiologic alterations.
Jong Ho Kim +4 more
doaj +1 more source
ABSTRACT Myotonic dystrophy type 1 (DM1) presents significant anesthetic challenges. A 46‐year‐old woman with DM1 underwent emergent exploratory laparotomy. This case highlights the importance of conservative neuromuscular blocker dosing, quantitative neuromuscular monitoring, clinically‐guided timing of sugammadex administration, careful airway ...
Yun Chin Lin +7 more
wiley +1 more source
Continuous intraoperative nerve monitoring (IONM) in transcervical inflatable mediastinoscopic esophagectomy may help identify and protect RLN. ABSTRACT Transcervical inflatable mediastinoscopic esophagectomy (TIME), with fewer incisions and without going through the thoracic cavity, may achieve the same results and lymph node dissection compared with ...
Luo Zhao +5 more
wiley +1 more source
Pharmacological Characteristics of the Inhibition of Nondepolarizing Neuromuscular Blocking Agents at Human Adult Muscle Nicotinic Acetylcholine Receptor [PDF]
Background Nondepolarizing neuromuscular blocking agents (NMBAs) are classic competitive-inhibitors at the muscle nicotinic acetylcholine receptor (nAChR). Although the fetal subtype muscle nAChR has been extensively studied at a molecular level, less is known about the interaction between nondepolarizing NMBAs and the human ...
Malin, Jonsson Fagerlund +2 more
openaire +2 more sources
In this real‐world study among 14,459 adults with MG, exposure to any contraindicated treatment was not significantly associated with risk of ICU admission for MG but was associated with significantly higher risk of death. In contrast, statins were associated with a greater risk of ICU admission but a lower risk of death.
Guilhem Solé +7 more
wiley +1 more source
A Case of Malignant Hyperthermia Following Intubation With Rocuronium
Background Malignant hyperthermia (MH) is an inherited autosomal‐dominant disorder of ryanodine receptors. While typically associated with exposure to inhaled anesthetics or depolarizing neuromuscular blocking agents (NMBAs), there have been reported cases following exposure to other conditions and medications including nondepolarizing neuromuscular ...
Kristin Woodring +4 more
wiley +1 more source
Background Immune‐mediated necrotizing myopathy causes progressive muscle weakness and may complicate anesthetic management because responses to neuromuscular blocking agents may be unpredictable and residual blockade may further compromise respiratory function. We report a case in which laparoscopic surgery was completed without neuromuscular blocking
Yuka Kobayashi +3 more
wiley +1 more source
A postintubation tracheal stenotic patient who requires surgical resection and anastomosis is a challenging case for an anesthesiologist, requiring meticulous planning during surgical correction due to a shared airway. This case report is about the anesthetic management of a 23‐year‐old male who developed severe tracheal stenosis following prolonged ...
Mohammad Zishan Uddin +7 more
wiley +1 more source

