Results 1 to 10 of about 91,692 (300)

Synaptic boutons sizes are tuned to best fit their physiological performances [PDF]

open access: yes, 2013
To truly appreciate the myriad of events which relate synaptic function and vesicle dynamics, simulations should be done in a spatially realistic environment. This holds true in particular in order to explain as well the rather astonishing motor patterns
Bucher, Dan   +7 more
core   +1 more source

Pathogenesis of myasthenia gravis: update on disease types, models, and mechanisms [version 1; referees: 2 approved]

open access: yesF1000Research, 2016
Myasthenia gravis is an autoimmune disease of the neuromuscular junction (NMJ) caused by antibodies that attack components of the postsynaptic membrane, impair neuromuscular transmission, and lead to weakness and fatigue of skeletal muscle.
William D. Phillips, Angela Vincent
doaj   +1 more source

The selectivity and specificity of autophagy in drosophila [PDF]

open access: yes, 2012
Autophagy is a process of cellular self-degradation and is a major pathway for elimination of cytoplasmic material by the lysosomes. Autophagy is responsible for the degradation of damaged organelles and protein aggregates and therefore plays a ...
Chou   +27 more
core   +2 more sources

Simultaneous Combined Myositis, Inflammatory Polyneuropathy, and Overlap Myasthenic Syndrome

open access: yesCase Reports in Neurological Medicine, 2016
Immune-mediated neuromuscular disorders include pathologies of the peripheral nervous system, neuromuscular junction, and muscles. If overlap syndromes (or the association of almost two autoimmune disorders) are recognized, the simultaneous occurrence of
Stéphane Mathis   +7 more
doaj   +1 more source

Altered Function of the DnaJ Family Cochaperone DNJ-17 Modulates Locomotor Circuit Activity in a Caenorhabditis elegans Seizure Model. [PDF]

open access: yes, 2016
The highly conserved cochaperone DnaJ/Hsp40 family proteins are known to interact with molecular chaperone Hsp70, and can regulate many cellular processes including protein folding, translocation, and degradation.
Jin, Yishi, Takayanagi-Kiya, Seika
core   +2 more sources

A virtual laboratory system for physiology teaching [PDF]

open access: yes, 1995
The problem of understanding physiological processes can be aided by visualization tools. Traditionally this has been achieved by the use of schematic paper diagrams. However, many physiological processes are quite complex, and in many instances students
Bohme, Karl   +3 more
core   +3 more sources

Prenatal diagnosis and genetic analysis of fetal akinesia deformation sequence and multiple pterygium syndrome associated with neuromuscular junction disorders: A review

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2012
Fetal akinesia deformation sequence is a clinically and genetically heterogeneous disorder characterized by a variable combination of arthrogryposis, fetal akinesia, intrauterine growth restriction, developmental abnormalities such as cystic hygroma ...
Chih-Ping Chen
doaj   +1 more source

Neuro-Protection and Neuro-Therapy Effects of Acalypha Indica Linn. Water Extract Ex Vivo on Musculus Gastrocnemius Frog [PDF]

open access: yes, 2008
The studies of neuro-protection and neuro-therapy effects of Acalypha indica Linn. water extract ex vivo on Musculus gastrocnemius frog have already done at three Departments in Faculty of Medicine, University of Indonesia.
Ibrahim, N. (Nurhadi)   +3 more
core   +1 more source

Profile of sugammadex for reversal of neuromuscular blockade in the elderly: Current perspectives [PDF]

open access: yes, 2017
The number of elderly patients is increasing worldwide. This will have a significant impact on the practice of anesthesia in future decades. Anesthesiologists must provide care for an increasing number of elderly patients, who have an elevated risk of ...
Bertoncello, Francesco   +2 more
core   +1 more source

Skeletal muscle mTORC1 regulates neuromuscular junction stability

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2020
Background Skeletal muscle is a plastic tissue that can adapt to different stimuli. It is well established that Mammalian Target of Rapamycin Complex 1 (mTORC1) signalling is a key modulator in mediating increases in skeletal muscle mass and function ...
Martina Baraldo   +12 more
doaj   +1 more source

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