Results 31 to 40 of about 442,682 (288)

Temperature sensitivity of the pyloric neuromuscular system and its modulation by dopamine [PDF]

, 2013
We report here the effects of temperature on the p1 neuromuscular system of the stomatogastric system of the lobster (Panulirus interruptus). Muscle force generation, in response to both the spontaneously rhythmic in vitro pyloric network neural activity
Kevin H. Hobbs, Burstein, Helaine J., Hooper, Scott L., Jeffrey B Thuma, Kevin H Hobbs, Seiter, Natasha S., Scott L. Hooper, Hobbs, Kevin H., Natasha S. Seiter, Scott L Hooper, Natasha S Seiter, Jeffrey B. Thuma, Helaine J. Burstein, Thuma, Jeffrey B., Helaine J Burstein   +14 more
core   +2 more sources

"Warming yang and invigorating qi" acupuncture alters acetylcholine receptor expression in the neuromuscular junction of rats with experimental autoimmune myasthenia gravis

Neural Regeneration Research, 2016
Myasthenia gravis is an autoimmune disorder in which antibodies have been shown to form against the nicotinic acetylcholine nicotinic postsynaptic receptors located at the neuromuscular junction.
Hai-peng Huang, Hong Pan, Hong-feng Wang
doaj   +1 more source

Measuring Neuromuscular Junction Functionality [PDF]

Journal of Visualized Experiments, 2017
Neuromuscular junction (NMJ) functionality plays a pivotal role when studying diseases in which the communication between motor neuron and muscle is impaired, such as aging and amyotrophic lateral sclerosis (ALS). Here we describe an experimental protocol that can be used to measure NMJ functionality by combining two types of electrical stimulation ...
Rizzuto, Emanuele, Pisu, Simona, Nicoletti, Carmine, Del Prete, Zaccaria, Musaro, Antonio   +4 more
openaire   +2 more sources

Internalization of Muscle-Specific Kinase Is Increased by Agrin and Independent of Kinase-Activity, Lrp4 and Dynamin

Frontiers in Molecular Neuroscience, 2022
Muscle-specific kinase (MuSK) is a receptor tyrosine kinase absolutely required for neuromuscular junction formation. MuSK is activated by binding of motor neuron-derived Agrin to low-density lipoprotein receptor related protein 4 (Lrp4), which forms a ...
Anna Gemza, Cinzia Barresi, Jakob Proemer, Jasmin Hatami, Margarita Lazaridis, Ruth Herbst   +5 more
doaj   +1 more source

Muscle specific kinase (MuSK) activation preserves neuromuscular junctions in the diaphragm but is not sufficient to provide a functional benefit in the SOD1G93A mouse model of ALS

Neurobiology of Disease, 2019
Amyotrophic lateral sclerosis (ALS), a neurodegenerative disease affecting motor neurons, is characterized by rapid decline of motor function and ultimately respiratory failure.
Arundhati Sengupta-Ghosh, Sara L. Dominguez, Luke Xie, Kai H. Barck, Zhiyu Jiang, Timothy Earr, Jose Imperio, Lilian Phu, Hanna G. Budayeva, Donald S. Kirkpatrick, Hao Cai, Jeffrey Eastham-Anderson, Hai Ngu, Oded Foreman, Maj Hedehus, Michael Reichelt, Isidro Hotzel, Yonglei Shang, Richard A.D. Carano, Gai Ayalon, Amy Easton   +20 more
doaj   +1 more source

Synaptic boutons sizes are tuned to best fit their physiological performances [PDF]

, 2013
To truly appreciate the myriad of events which relate synaptic function and vesicle dynamics, simulations should be done in a spatially realistic environment. This holds true in particular in order to explain as well the rather astonishing motor patterns
Dan Bucher, Alfio Grillo, Christoph Schuster, Bucher, Dan, Geiger, Romina, Grillo, Alfio, Lihao Ge, Knodel, Markus Michael, Queisser, Sean Gillian, Markus M Knodel, Romina Geiger, Ge, Lihao, Gillian Queisser, Schuster, Christoph M., Wittum, Gabriel, Gabriel Wittum   +15 more
core   +1 more source

Regulatory Function of Sympathetic Innervation on the Endo/Lysosomal Trafficking of Acetylcholine Receptor

Frontiers in Physiology, 2021
Recent studies have demonstrated that neuromuscular junctions are co-innervated by sympathetic neurons. This co-innervation has been shown to be crucial for neuromuscular junction morphology and functional maintenance. To improve our understanding of how
Tatjana Straka, Tatjana Straka, Tatjana Straka, Charlotte Schröder, Andreas Roos, Andreas Roos, Laxmikanth Kollipara, Albert Sickmann, Albert Sickmann, Albert Sickmann, Marion Patrick Ivey Williams, Mathias Hafner, Muzamil Majid Khan, Muzamil Majid Khan, Muzamil Majid Khan, Rüdiger Rudolf, Rüdiger Rudolf, Rüdiger Rudolf   +17 more
doaj   +1 more source

Synaptic bouton sizes are tuned to best fit their physiological performances : poster presentation from Twentieth Annual Computational Neuroscience Meeting: CNS*2011, Stockholm, Sweden, 23 - 28 July 2011 [PDF]

, 2011
Poster presentation from Twentieth Annual Computational Neuroscience Meeting: CNS*2011 Stockholm, Sweden. 23-28 July 2011. To truly appreciate the myriad of events which relate synaptic function and vesicle dynamics, simulations should be done in a ...
Markus Knodel, Dan Bucher, Alfio Grillo, Christoph Schuster, Bucher, Dan, Geiger, Romina, Ge, Lee How, Grillo, Alfio, Knodel, Markus Michael, Queisser, Sean Gillian, Romina Geiger, Lee How Ge, Gillian Queisser, Schuster, Christoph M., Wittum, Gabriel, Gabriel Wittum, Lee Ge   +16 more
core   +1 more source

Systematic review of mitochondrial dysfunction and oxidative stress in aging: A focus on neuromuscular junctions

Neural Regeneration Research
Mitochondrial dysfunction and oxidative stress are widely regarded as primary drivers of aging and are associated with several neurodegenerative diseases.
Senlin Chai, Ning Zhang, Can Cui, Zhengyuan Bao, Qianjin Wang, Wujian Lin, Ronald Man Yeung Wong, Sheung Wai Law, Rebecca Schönmehl, Christoph Brochhausen, Wing Hoi Cheung   +10 more
doaj   +1 more source

Functional characterization of MuSK, receptor tyrosine kinase required for the formation and the maintenance of nerve-muscle synapses : "in vivo" and "in vitro" approaches [PDF]

, 2008
The developing neuromuscular junction (NMJ) serves as one of the best model systems for studying synapse formation since changes in shape, size, and molecular composition can be followed with high spatial and temporal resolution.
Maj, Marcin
core   +1 more source