Total ganglioside ablation at mouse motor nerve terminals alters neurotransmitter release level [PDF]
Neuronal membrane gangliosides, forming a large family of sialylated glycosphingolipids, have been hypothesized to play important roles in synaptic transmission.
Furukawa, K. +4 more
core +1 more source
NAD+ improves neuromuscular development in a zebrafish model of FKRP-associated dystroglycanopathy
Background Secondary dystroglycanopathies are muscular dystrophies that result from mutations in genes that participate in Dystroglycan glycosylation.
Erin C. Bailey +9 more
doaj +1 more source
Juvenile Neuromuscular Systems Show Amplified Disturbance to Muscle Unloading
Muscle unloading results in severe disturbance in neuromuscular function. During juvenile stages of natural development, the neuromuscular system experiences a high degree of plasticity in function and structure.
Michael R. Deschenes +5 more
doaj +1 more source
DOXAPRAM AND THE NEUROMUSCULAR JUNCTION †
We have studied the action of doxapram on neuromuscular transmission in the rat phrenic nerve-diaphragm preparation. Doxapram augmented neuromuscular transmission in a dose-related manner when a threshold concentration of 5 x 10(-5) mol litre-1 had been exceeded.
B J, Pollard, N P, Randall, B J, Pleuvry
openaire +2 more sources
Neuromuscular synaptic function in mice lacking major subsets of gangliosides [PDF]
Gangliosides are a family of sialylated glycosphingolipids enriched in the outer leaflet of neuronal membranes, in particular at synapses. Therefore, they have been hypothesized to play a functional role in synaptic transmission.
Furukawa, K. +12 more
core +1 more source
Agrin promotes acetylcholine receptor clustering at the mammalian neuro-muscular junction by PI3K/GSK3ß²-mediated regulation of +TIPs and microtubule capture [PDF]
Neurotransmission an der neuromuskulären Endplatte von Säugetieren erfolgt durch Ausschüttung von Acetylcholin (ACh) aus motorischen Nerven in den synaptischen Spalt und verursacht letztendlich Muskelkontraktion im angesteuerten Muskel.
Sladecek, Stefan
core +1 more source
Temperature sensitivity of the pyloric neuromuscular system and its modulation by dopamine [PDF]
We report here the effects of temperature on the p1 neuromuscular system of the stomatogastric system of the lobster (Panulirus interruptus). Muscle force generation, in response to both the spontaneously rhythmic in vitro pyloric network neural activity
Kevin H. Hobbs +14 more
core +1 more source
THE NEUROMUSCULAR JUNCTION DISORDERS [PDF]
Neuromuscular junction (NMJ) disorders result from destruction, malfunction or absence of one or more key proteins involved in neuromuscular transmission, illustrated diagrammatically in fig 1. The most common pathology is antibody mediated damage or down regulation of ion channels or receptors, resulting in myasthenia gravis (MG), Lambert-Eaton ...
openaire +2 more sources
Myasthenia gravis is an autoimmune disorder in which antibodies have been shown to form against the nicotinic acetylcholine nicotinic postsynaptic receptors located at the neuromuscular junction.
Hai-peng Huang, Hong Pan, Hong-feng Wang
doaj +1 more source
Neuromuscular junction dysfunction in Lafora disease [PDF]
Monica Shukla +2 more
doaj +2 more sources

