Results 21 to 30 of about 461,814 (280)
Chronic aryl hydrocarbon receptor activity phenocopies smoking‐induced skeletal muscle impairment
Journal of Cachexia, Sarcopenia and Muscle, 2022 Background Chronic obstructive pulmonary disease (COPD) patients exhibit skeletal muscle atrophy, denervation, and reduced mitochondrial oxidative capacity.
Trace Thome +15 more
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Denervation-Related Neuromuscular Junction Changes: From Degeneration to Regeneration
Frontiers in Molecular Neuroscience, 2022 Neuromuscular junctions (NMJs) are the key interface between terminal nerves and targeted muscle, which undergo degeneration during denervation periods. Denervation-related NMJs changes limits the recovery level of nerve repair strategies.
Xinying Huang +9 more
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NAD+ improves neuromuscular development in a zebrafish model of FKRP-associated dystroglycanopathy
Skeletal Muscle, 2019 Background Secondary dystroglycanopathies are muscular dystrophies that result from mutations in genes that participate in Dystroglycan glycosylation.
Erin C. Bailey +9 more
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Juvenile Neuromuscular Systems Show Amplified Disturbance to Muscle Unloading
Frontiers in Physiology, 2021 Muscle unloading results in severe disturbance in neuromuscular function. During juvenile stages of natural development, the neuromuscular system experiences a high degree of plasticity in function and structure.
Michael R. Deschenes +5 more
doaj +1 more source
DOXAPRAM AND THE NEUROMUSCULAR JUNCTION †
British Journal of Anaesthesia, 1989 We have studied the action of doxapram on neuromuscular transmission in the rat phrenic nerve-diaphragm preparation. Doxapram augmented neuromuscular transmission in a dose-related manner when a threshold concentration of 5 x 10(-5) mol litre-1 had been exceeded.
B J, Pollard, N P, Randall, B J, Pleuvry
openaire +2 more sources
Neural Regeneration Research, 2016 Myasthenia gravis is an autoimmune disorder in which antibodies have been shown to form against the nicotinic acetylcholine nicotinic postsynaptic receptors located at the neuromuscular junction.
Hai-peng Huang, Hong Pan, Hong-feng Wang
doaj +1 more source
Measuring Neuromuscular Junction Functionality [PDF]
Journal of Visualized Experiments, 2017 Neuromuscular junction (NMJ) functionality plays a pivotal role when studying diseases in which the communication between motor neuron and muscle is impaired, such as aging and amyotrophic lateral sclerosis (ALS). Here we describe an experimental protocol that can be used to measure NMJ functionality by combining two types of electrical stimulation ...
Rizzuto, Emanuele +4 more
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Neuromuscular synaptic function in mice lacking major subsets of gangliosides [PDF]
, 2008 Gangliosides are a family of sialylated glycosphingolipids enriched in the outer leaflet of neuronal membranes, in particular at synapses. Therefore, they have been hypothesized to play a functional role in synaptic transmission.
Furukawa, K. +12 more
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Mitochondrial Mechanisms of Neuromuscular Junction Degeneration with Aging
Cells, 2020 Skeletal muscle deteriorates with aging, contributing to physical frailty, poor health outcomes, and increased risk of mortality. Denervation is a major driver of changes in aging muscle.
Maria-Eleni Anagnostou +1 more
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SYNAPTIC VESICLES AND TRANSMITTER RELEASE AT THE NEUROMUSCULAR JUNCTION.
, 1982 SYNAPTIC VESICLES AND TRANSMITTER RELEASE AT THE NEUROMUSCULAR ...
CHARLES KENNETH. MESHUL (7981586)
core +4 more sources