Rejuvenation of the aged neuromuscular junction by exercise [PDF]
Cell Stress, 2018 Age-dependent declines in muscle function are observed across species. The loss of mobility resulting from the decline in muscle function represents an important health issue and a key determinant of quality of life for the elderly.
Tabita Kreko-Pierce, Benjamin A. Eaton
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Autoimmune Channelopathies at Neuromuscular Junction [PDF]
Frontiers in Neurology, 2019 The neuromuscular junction, also called myoneural junction, is a site of chemical communication between a nerve fiber and a muscle cell. There are many types of channels at neuromuscular junction that play indispensable roles in neuromuscular signal ...
Kun Huang +3 more
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A synaptic nidogen: Developmental regulation and role of nidogen-2 at the neuromuscular junction [PDF]
Neural Development, 2008 Background The skeletal neuromuscular junction is a useful model for elucidating mechanisms that regulate synaptogenesis. Developmentally important intercellular interactions at the neuromuscular junction are mediated by the synaptic portion of a basal ...
Smyth Neil +3 more
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Role of Neuromuscular Junction Monitoring in Management of a Postpartum Eclamptic Patient with Iatrogenic Hypermagnesemia [PDF]
The Indian Anaesthetists' Forum, 2010 Accidental hypermagnesemia is a common and often missed complication during treatment in a postpartum eclamptic patient. As symptomatic hypermagnesemia leads to neuromuscular junction blockade, neuromuscular junction monitoring serves the purpose of ...
Harshel G Parikh, Chitra B Upasani
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Autoantibody Testing in Neuromuscular Disorders [PDF]
, 2022 Autoantibodies are present in many autoimmune disorders, including diseases impacting the peripheral nerve, neuromuscular junction, and muscle. Some of these autoantibodies play a vital role in pathogenesis, whereas others are unlikely to be directly ...
김승우, 신하영
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PGC-1alpha regulates the neuromuscular junction program and ameliorates Duchenne muscular dystrophy [PDF]
, 2007 The coactivator PGC-1alpha mediates key responses of skeletal muscle to motor nerve activity. We show here that neuregulin-stimulated phosphorylation of PGC-1alpha and GA-binding protein (GABP) allows recruitment of PGC-1alpha to the GABP complex and ...
Handschin, C. +11 more
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Chronic aryl hydrocarbon receptor activity phenocopies smoking‐induced skeletal muscle impairment
Journal of Cachexia, Sarcopenia and Muscle, 2022 Background Chronic obstructive pulmonary disease (COPD) patients exhibit skeletal muscle atrophy, denervation, and reduced mitochondrial oxidative capacity.
Trace Thome +15 more
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Neural Regeneration Research, 2021 Myasthenia gravis is a rare and invalidating disease affecting the neuromuscular junction of voluntary muscles. The classical form of this autoimmune disease is characterized by the presence of antibodies against the most abundant protein in the ...
Francisco J Barrantes
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Differential localization of glutamate receptor subunits at the drosophila neuromuscular junction [PDF]
, 2004 The subunit composition of postsynaptic neurotransmitter receptors is a key determinant of synaptic physiology. Two glutamate receptor subunits, Drosophila glutamate receptor IIA (DGluRIIA) and DGluRIIB, are expressed at the Drosophila neuromuscular ...
Portman, Scott L. +5 more
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Denervation-Related Neuromuscular Junction Changes: From Degeneration to Regeneration
Frontiers in Molecular Neuroscience, 2022 Neuromuscular junctions (NMJs) are the key interface between terminal nerves and targeted muscle, which undergo degeneration during denervation periods. Denervation-related NMJs changes limits the recovery level of nerve repair strategies.
Xinying Huang +9 more
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