Results 11 to 20 of about 461,814 (280)

Rejuvenation of the aged neuromuscular junction by exercise [PDF]

open access: yesCell Stress, 2018
Age-dependent declines in muscle function are observed across species. The loss of mobility resulting from the decline in muscle function represents an important health issue and a key determinant of quality of life for the elderly.
Tabita Kreko-Pierce, Benjamin A. Eaton
doaj   +2 more sources

Autoimmune Channelopathies at Neuromuscular Junction [PDF]

open access: yesFrontiers in Neurology, 2019
The neuromuscular junction, also called myoneural junction, is a site of chemical communication between a nerve fiber and a muscle cell. There are many types of channels at neuromuscular junction that play indispensable roles in neuromuscular signal ...
Kun Huang   +3 more
doaj   +2 more sources

A synaptic nidogen: Developmental regulation and role of nidogen-2 at the neuromuscular junction [PDF]

open access: yesNeural Development, 2008
Background The skeletal neuromuscular junction is a useful model for elucidating mechanisms that regulate synaptogenesis. Developmentally important intercellular interactions at the neuromuscular junction are mediated by the synaptic portion of a basal ...
Smyth Neil   +3 more
doaj   +2 more sources

Role of Neuromuscular Junction Monitoring in Management of a Postpartum Eclamptic Patient with Iatrogenic Hypermagnesemia [PDF]

open access: yesThe Indian Anaesthetists' Forum, 2010
Accidental hypermagnesemia is a common and often missed complication during treatment in a postpartum eclamptic patient. As symptomatic hypermagnesemia leads to neuromuscular junction blockade, neuromuscular junction monitoring serves the purpose of ...
Harshel G Parikh, Chitra B Upasani
doaj   +1 more source

Total ganglioside ablation at mouse motor nerve terminals alters neurotransmitter release level [PDF]

open access: yes, 2010
Neuronal membrane gangliosides, forming a large family of sialylated glycosphingolipids, have been hypothesized to play important roles in synaptic transmission.
Furukawa, K.   +4 more
core   +2 more sources

Neuromuscular junction signalling

open access: yes, 2009
A Powerpoint slide of an animated cartoon of acetylcholine signal transmission at a neuromuscular ...
Verna Lavender
core   +4 more sources

PGC-1alpha regulates the neuromuscular junction program and ameliorates Duchenne muscular dystrophy [PDF]

open access: yes, 2007
The coactivator PGC-1alpha mediates key responses of skeletal muscle to motor nerve activity. We show here that neuregulin-stimulated phosphorylation of PGC-1alpha and GA-binding protein (GABP) allows recruitment of PGC-1alpha to the GABP complex and ...
Handschin, C.   +11 more
core   +1 more source

Autoantibody Testing in Neuromuscular Disorders [PDF]

open access: yes, 2022
Autoantibodies are present in many autoimmune disorders, including diseases impacting the peripheral nerve, neuromuscular junction, and muscle. Some of these autoantibodies play a vital role in pathogenesis, whereas others are unlikely to be directly ...
김승우   +3 more
core   +1 more source

Agrin regulates CLASP2-mediated capture of microtubules at the neuromuscular junction synaptic membrane [PDF]

open access: yes, 2012
Agrin is the major factor mediating the neuronal regulation of postsynaptic structures at the vertebrate neuromuscular junction, but the details of how it orchestrates this unique three-dimensional structure remain unknown.
Jeffrey van Haren   +47 more
core   +1 more source

Possible implications of dysregulated nicotinic acetylcholine receptor diffusion and nanocluster formation in myasthenia gravis

open access: yesNeural Regeneration Research, 2021
Myasthenia gravis is a rare and invalidating disease affecting the neuromuscular junction of voluntary muscles. The classical form of this autoimmune disease is characterized by the presence of antibodies against the most abundant protein in the ...
Francisco J Barrantes
doaj   +1 more source

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