Results 11 to 20 of about 861 (215)

Novel drug development for neuromuscular blockade

Journal of Anaesthesiology Clinical Pharmacology, 2016
Pharmacological advances in anesthesia in recent decades have resulted in safer practice and better outcomes. These advances include improvement in anesthesia drugs with regard to efficacy and safety profiles.
Amit Prabhakar, Alan D Kaye, Melville Q Wyche, Orlando J Salinas, Kenneth Mancuso, Richard D Urman   +5 more
doaj   +1 more source

Neuromuscular block in patients 80 years and older: a prospective, controlled study

BMC Anesthesiology, 2021
Background An increasing number of patients older than 80 years are undergoing anesthesia, but little information is available regarding pharmacodynamic effects of myorelaxants in this population.
Denis Schmartz, Raouf Sghaier, Paul Bernard, Jean François Fils, Thomas Fuchs-Buder   +4 more
doaj   +1 more source

National survey on the use of neuromuscular blockers and reversal in adult, pediatric and pregnant patients. [PDF]

Pediatric Anesthesia and Critical Care Journal (PACCJ)
Introduction This study presents the findings of an Italian investiga- tion through SIAATIP - Italian Society of Anesthesia, Analgesia and Pediatric Intensive Care - aimed at gather- ing data on current anesthetic practices related to the use of ...
A. Federici, M Ciuffreda, E. Pisello, S. Sorrenti, L. Brugiaferri, G. Montenero, G. Sfregola, A. Ragone, C. Piangatelli, D. Galante   +9 more
doaj   +1 more source

Deep Neuromuscular Blockade During General Anesthesia: Advantages, Challenges, and Future Directions

Anesthesia Research
Background: Neuromuscular blocking agents play an important role in modern anesthesia by facilitating optimal surgical conditions through deep muscle relaxation.
Jacob Rosenberg, Thomas Fuchs-Buder
doaj   +1 more source

Reversal agents in anaesthesia and critical care

Indian Journal of Anaesthesia, 2015
Despite the advent of short and ultra-short acting drugs, an in-depth knowledge of the reversal agents used is a necessity for any anaesthesiologist.
Nibedita Pani, Pradeep A Dongare, Rajeeb Kumar Mishra   +2 more
doaj   +1 more source

Critical Care Nurses' Performance Regarding Use of Neuromuscular Blocking Agents in Patients with Respiratory Failure [PDF]

Helwan International Journal for Nursing Research and Practice
:Background: The respiratory system provides oxygen to and removes carbon dioxide from the body however the inability to perform either or both of these tasks results in respiratory failure. Aim: The present study aimed to assess the critical care nurses'
Shimaa Ali, Alshaimaa Abouzaid, Baghdad Mahmoud   +2 more
doaj   +1 more source

Feasibility of intraoperative quantitative neuromuscular blockade monitoring in children using electromyography

Saudi Journal of Anaesthesia, 2022
Background: Quantitative train-of-four (TOF) monitoring remains essential in optimizing anesthetic outcomes by assessing the depth and recovery from neuromuscular blockade. Despite this, residual neuromuscular blockade, defined as a TOF ratio
Kwaku Owusu-Bediako, Ryan Munch, Jay Mathias, Joseph D Tobias   +3 more
doaj   +1 more source

Newer Neuromuscular Blocking Agents [PDF]

Pharmacology & Toxicology, 1994
Four neuromuscular blocking drugs, doxacurium, mivacurium, pipecuronium, and rocuronium have been or are about to be introduced into clinical practice. The purpose of this MiniReview is to describe their pharmacology, to consider their place in clinical anaesthetic practice, and to examine whether the needs of the clinican have been met.
openaire   +2 more sources

Neuromuscular blockade and their monitoring in the intensive care unit: a multicenter observational prospective study

Annals of Intensive Care
Background: Neuromuscular blocking agents may improve outcomes in specific conditions, including the early phase of acute respiratory distress syndrome.
Bertrand Hermann, Guillaume Decormeille, Tiphanie Gobé, Nathanaël Mangeard, Adel Maamar, Saria Sayadi, Bénédicte Pernod, Nadine Robquin, Jean-Pierre Ponthus, Sophie Le Potier, Pierre Bouju, Angélique Balabanian, Antoine Frouin, Sébastien Moschietto, Gwenaelle Jacq, Emeline Villemont, Clémence Houbé, Anaïs Queyreau, Célina Morand, Florence Boissier, Jean-Baptiste Lascarrou, Sabine Valera, Sami Hraiech, Laure Clouet, Gaël Piton, Cindérella Noël, Anne Joosten, Cécilia Tabra Osorio, Adrien Constan, Jérôme Cecchini, Gwennaelle Mercier, Arnaud Bruyneel, Chloé Villamaux, François Pousset, Nicholas Heming, Laurent Poiroux, Jean-François Llitjos, Saber Davide Barbar   +37 more
doaj   +1 more source

Comparison of the neuromuscular effects of two infusion rates of rocuronium in anesthetized pigs

Acta Veterinaria Scandinavica, 2022
Background: Neuromuscular blocking agents are frequently administered to pigs used for research. In humans, administration of the drugs is not without risk and may result in accidental awareness under general anaesthesia and postoperative residual ...
Kamilla Pedersen, Linda Loisa Kruhøffer, Jens Lykkesfeldt, Birgitte Saima Kousholt   +3 more
doaj   +1 more source