Results 21 to 30 of about 50,619 (166)

Association between levobupivacaine and pancuronium. Interference in neuromuscular transmission and blockade in rats [PDF]

Acta Cirúrgica Brasileira, 2016
PURPOSE: To evaluate the effects of levobupivacaine on neuromuscular transmission and neuromuscular blockade produced by pancuronium in vitro. METHODS: Thirty rats were distributed into groups (n = 5) according to the drug used alone or in combination:
Vanessa Henriques Carvalho, Angélica de Fátima de Assunção Braga, Franklin Sarmento da Silva Braga, Gloria Maria Braga Potério, Filipe Nadir Caparica Santos, Fernando Eduardo Féres Junqueira   +5 more
doaj   +2 more sources

Preparing for the unexpected: special considerations and complications after sugammadex administration

BMC Anesthesiology, 2017
Sugammadex, a modified gamma-cyclodextrin, has changed clinical practice of neuromuscular reversal dramatically. With the introduction of this selective relaxant binding agent, rapid and reliable neuromuscular reversal from any depth of block became ...
Hajime Iwasaki, J. Ross Renew, Takayuki Kunisawa, Sorin J. Brull   +3 more
doaj   +1 more source

Carboxymethyl-γ-cyclodextrin, a novel selective relaxant binding agent for the reversal of neuromuscular block induced by aminosteroid neuromuscular blockers: an ex vivo laboratory study

BMC Anesthesiology, 2021
Background Residual neuromuscular block at the end of surgery may compromise the patient’s safety. The risk of airway complications can be minimized through monitoring of neuromuscular function and reversal of neuromuscular block if needed.
Ákos I. Fábián, Edömér Tassonyi, Vera Csernoch, Marianna Fedor, Tamás Sohajda, Lajos Szente, Béla Fülesdi   +6 more
doaj   +1 more source

Newer Neuromuscular Blocking Agents [PDF]

Pharmacology & Toxicology, 1994
Four neuromuscular blocking drugs, doxacurium, mivacurium, pipecuronium, and rocuronium have been or are about to be introduced into clinical practice. The purpose of this MiniReview is to describe their pharmacology, to consider their place in clinical anaesthetic practice, and to examine whether the needs of the clinican have been met.
openaire   +2 more sources

Intravenous immunoglobulin is safe and effective in controlling pre-existing paraneoplastic neuromuscular diseases in cancer patients treated with immune checkpoint inhibitors: two case reports and literature review

Frontiers in Oncology, 2023
Immune checkpoint inhibitors cause rare but potentially fatal neuromuscular complications, leading to a concern to use these agents in cancer patients with pre-existing autoimmune or inflammatory neuromuscular diseases.
Ge Xiong, Richard Benjamin Young, Helen Chow, Emanual Maverakis, Ricardo A. Maselli, David Paul Richman, Tianhong Li   +6 more
doaj   +1 more source

Neuromuscular Blocking Agents

Journal of Pharmacy and Pharmacology, 1958
Abstract The preparation of two further NSN-tris-ethonium compounds, 9-ethyl-9-thioniaheptadecylenebis(triethylammonium) triiodide (dioctasulphonium triethiodide; DOSE) and 11-ethyl-11-thioniaheneicosylenebis(triethylammonium) triiodide (didecasulphonium triethiodide; DDSE) is described.
D Edwards, J J Lewis, J B Stenlake, M S Zoha   +3 more
openaire   +2 more sources

ClC-1 Inhibition as a Mechanism for Accelerating Skeletal Muscle Recovery After Neuromuscular Block in Rats

Nature Communications
Neuromuscular blocking agents are used commonly to induce skeletal muscle relaxation during surgery. While muscle relaxation facilitates surgical procedures and tracheal intubation, adequate recovery of muscle function after surgery is required to ...
Marianne Skals, Martin Broch-Lips, Martin Brandhøj Skov, Anders Riisager, Judith Ceelen, Ole Bækgaard Nielsen, Sorin J. Brull, Hans D. de Boer, Thomas Holm Pedersen   +8 more
doaj   +1 more source

MONITORING OF VARIOUS TYPES OF NEUROMUSCULAR BLOCKADE

Вестник анестезиологии и реаниматологии, 2018
Goal of the review: to build up the current understanding of electrophysiological specific features of various neuromuscular blockades. Having analyzed the results of multiple studies devoted to investigation of the impact of various medications ...
N. V. Chubchenko, K. M. Lebedinskiy
doaj   +1 more source

Considerations in Neuromuscular Blockade in the ICU: A Case Report and Review of the Literature

Case Reports in Critical Care, 2020
Neuromuscular blocking agents are regularly used in the intensive care unit (ICU) to facilitate mechanical ventilation in patients with acute respiratory distress syndrome and patient-ventilator dyssynchronies.
Jessica D. Workum, Stephanie H.V. Janssen, Hugo R.W. Touw   +2 more
doaj   +1 more source

BILE SALTS AND NEUROMUSCULAR BLOCKING AGENTS

British Journal of Anaesthesia, 1981
The influence of the primary bile salts taurocholate and chenodeoxycholate on the neuromuscular blockade of the non-depolarizing drugs Org 6368, pancuronium, Org NC 45 and hexafluorenium was studied in cats. An increase in the effects of these agents, all possessing widely varying molecular structures, was found following administration of the bile ...
WESTRA, P, HOUWERTJES, MC, WESSELING, H, MEIJER, DKF   +3 more
openaire   +3 more sources