Results 71 to 80 of about 43,202 (221)

The vapB-vapC operon of Acidovorax citrulli functions as a bona-fide toxin-antitoxin module

Frontiers in Microbiology, 2016
Toxin–antitoxin systems are commonly found on plasmids and chromosomes of bacteria and archaea. These systems appear as biscystronic genes encoding a stable toxin and a labile antitoxin, which protects the cells from the toxin’s activity. Under specific,
Reut eShavit, Mario eLebendiker, Zohar ePasternak, Saul eBurdman, Yael eHelman   +4 more
doaj   +1 more source

T3SS effector and regulator discovery by predicting interacting partners of T3SS chaperones in Pseudomonas aeruginosa

Protein Science, Volume 35, Issue 5, May 2026.
Abstract Pseudomonas aeruginosa is a prominent opportunistic pathogen whose virulence is closely linked to its Type III Secretion System (T3SS), a specialized apparatus that injects effector proteins into host cells. T3SS chaperones are essential for stabilizing, delivering, and regulating T3SS expression.
Jing Zhang
wiley   +1 more source

Detoxification of Peptide-Containing Biotoxins

Вестник войск РХБ защиты
Highlights. Peptide biotoxins are important problem for human health and as lethal agents due to their wild diversity of chemical structures and biological sources.Such peptide biotoxins and prion proteins can be effectively neutralized by different ...
Ilya V. Lyagin, Olga V. Maslova, Olga V. Senko, Nikolay A. Stepanov, Elena N. Efremenko   +4 more
doaj   +1 more source

Safety and Pharmacokinetics of a Four Monoclonal Antibody Combination Against Botulinum C and D Neurotoxins. [PDF]

, 2019
Botulism is caused by botulinum neurotoxin (BoNT), the most poisonous substance known. BoNTs are also classified as Tier 1 biothreat agents due to their high potency and lethality.
Cobb, Ronald R, Conrad, Fraser, Espinoza, Yero, Garcia-Rodriguez, Consuelo, Kimbler, Angie, Kraus, Carl N, Marks, James D, Martinez, Zachary, Pham, Khanh, Riling, Kathryn, Snow, Doris M, Tomic, Milan T, Wong, David   +12 more
core  

Nanoscopic evaluation to facilitate treatment of the proximal interphalangeal joint following a traumatic wound in a 4‐month‐old colt

Veterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract A 4‐month‐old Irish Draught colt was presented for treatment of a traumatic wound to the right hind pastern region of 6 hours’ duration. Investigation confirmed communication between the wound and the proximal interphalangeal joint. Due to the joint's small size, a traditional synovial endoscopic lavage could not be performed.
Jarred Green, John David Stack, Constance Bowkett‐Pritchard, Louise J. Breen, Alexandra Gillen   +4 more
wiley   +1 more source

Force for ancient and recent life: viral and stem-loop RNA consortia promote life. [PDF]

, 2014
Lytic viruses were thought to kill the most numerous host (i.e., kill the winner). But persisting viruses/defectives can also protect against viruses, especially in a ubiquitous virosphere. In 1991, Yarmolinsky et al.
Villarreal, Luis P
core   +1 more source

A Novel Small Molecule Accelerates Early Persister Regrowth and Potentiates Antibiotic Killing via MdtL–DcrB

Microbial Biotechnology, Volume 19, Issue 5, May 2026.
bymBDZ accelerates early regrowth of persister‐derived E. coli and potentiates antibiotic killing. Its activity requires the MdtL–DcrB axis and is associated with envelope‐linked transport changes that increase intracellular small‐molecule exposure during recovery, thereby enhancing clearance in early treatment windows. ABSTRACT Persister cells survive
Garin Park, Hyein Kim, Sooyeon Song
wiley   +1 more source

Phage ϕC2 mediates transduction of Tn6215, encoding erythromycin resistance, between Clostridium difficile strains [PDF]

, 2013
UNLABELLED: In this work, we show that Clostridium difficile phage ϕC2 transduces erm(B), which confers erythromycin resistance, from a donor to a recipient strain at a frequency of 10(-6) per PFU.
Chang, Barbara J, Emmett, Warren, Goh, Shan, Hussain, Haitham, Mullany, Peter, Riley, Thomas V   +5 more
core   +3 more sources

Microbiome of Apical Intracanal and Extraradicular Biofilms From the Same Roots of Teeth With Persistent Apical Periodontitis: An Observational Study

International Endodontic Journal, Volume 59, Issue 5, Page 806-818, May 2026.
ABSTRACT Aim Bacterial biofilms around the apex are crucial in disease progression and persistence of apical periodontitis. While intracanal biofilms initiate infection, extraradicular biofilms contribute to treatment resistance and persistence. Thus, a comprehensive understanding of these biofilms may help elucidate mechanisms underlying persistent ...
Yoko Asahi, Nanako Kuriki, Motoki Okamoto, Daisuke Motooka, Shota Nakamura, Hazuki Maezono, Kittipit Klanliang, Tsuyoshi Shimaoka, Tetsuya Iida, Shigeyuki Ebisu, Yuichiro Noiri, Mikako Hayashi   +11 more
wiley   +1 more source

Long-Term Pulmonary Damage in Surviving Antitoxin-Treated Mice following a Lethal Ricin Intoxication

Toxins
Ricin, a highly potent plant-derived toxin, is considered a potential bioterrorism weapon due to its pronounced toxicity, high availability, and ease of preparation.
Yoav Gal, Anita Sapoznikov, Shlomi Lazar, David Shoseyov, Moshe Aftalion, Hila Gutman, Yentl Evgy, Rellie Gez, Reinat Nevo, Reut Falach   +9 more
doaj   +1 more source