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Bacterial Toxins, Current Perspectives [PDF]
Toxins, 2020 Toxins are the major pathogenicity factors produced by numerous bacteria involved in severe diseases in humans and animals. Certain pathogenic bacteria synthesize only one toxin which is responsible for all the symptoms and outcome of the disease.
Michel R. Popoff
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Interactions between Autophagy and Bacterial Toxins: Targets for Therapy?
Toxins, 2015 Autophagy is a physiological process involved in defense mechanisms for clearing intracellular bacteria. The autophagic pathway is finely regulated and bacterial toxins interact with this process in a complex manner.
Jacques Mathieu
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Clostridial Neurotoxins: Structure, Function and Implications to Other Bacterial Toxins [PDF]
Microorganisms, 2021 Gram-positive bacteria are ancient organisms. Many bacteria, including Gram-positive bacteria, produce toxins to manipulate the host, leading to various diseases. While the targets of Gram-positive bacterial toxins are diverse, many of those toxins use a
Shuowei Cai, Raj Kumar, Bal Ram Singh
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Special Issue: Gram-Positive Bacterial Toxins [PDF]
Microorganisms, 2023 The Gram stain classifies most bacteria into one of two groups, Gram-negative or Gram-positive, based on the composition of their cell walls [...]
Shashi Sharma +2 more
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Impact of Bacterial Toxins in the Lungs [PDF]
Toxins, 2020 Bacterial toxins play a key role in the pathogenesis of lung disease. Based on their structural and functional properties, they employ various strategies to modulate lung barrier function and to impair host defense in order to promote infection. Although
Rudolf Lucas +13 more
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Some Examples of Bacterial Toxins as Tools [PDF]
ToxinsPathogenic bacteria produce diverse protein toxins to disturb the host’s defenses. This includes the opening of epithelial barriers to establish bacterial growth in deeper tissues of the host and to modulate immune cell functions.
Gudula Schmidt
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Bacterial Toxins for Cancer Therapy [PDF]
Toxins, 2017 Several pathogenic bacteria secrete toxins to inhibit the immune system of the infected organism. Frequently, they catalyze a covalent modification of specific proteins. Thereby, they block production and/or secretion of antibodies or cytokines. Moreover,
Nour-Imene Zahaf, Gudula Schmidt
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AB Toxins: A Paradigm Switch from Deadly to Desirable
Toxins, 2010 To ensure their survival, a number of bacterial and plant species have evolved a common strategy to capture energy from other biological systems. Being imperfect pathogens, organisms synthesizing multi-subunit AB toxins are responsible for the mortality ...
Oludare Odumosu +3 more
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The Glucocorticoid Receptor: A Revisited Target for Toxins
Toxins, 2010 The hypothalamic-pituitary-adrenal (HPA) axis activation and glucocorticoid responses are critical for survival from a number of bacterial, viral and toxic insults, demonstrated by the fact that removal of the HPA axis or GR blockade enhances mortality ...
Jeanette I. Webster Marketon +1 more
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Channel-Forming Bacterial Toxins in Biosensing and Macromolecule Delivery
Toxins, 2014 To intoxicate cells, pore-forming bacterial toxins are evolved to allow for the transmembrane traffic of different substrates, ranging from small inorganic ions to cell-specific polypeptides. Recent developments in single-channel electrical recordings,
Philip A. Gurnev +1 more
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