Results 21 to 30 of about 122,614 (250)
Two Clostridium perfringens Type E Isolates in France
Toxins, 2019 Clostridium perfringens type E is a less frequently isolated C. perfringens type and has not previously been reported in France. We have characterized two recent type E isolates, C.
Laure Diancourt +3 more
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Therapeutic Uses of Bacterial Subunit Toxins
Toxins, 2021 The B subunit pentamer verotoxin (VT aka Shiga toxin-Stx) binding to its cellular glycosphingolipid (GSL) receptor, globotriaosyl ceramide (Gb3) mediates internalization and the subsequent receptor mediated retrograde intracellular traffic of the AB5 ...
Clifford Lingwood
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Ecotoxicology and Environmental Safety, 2022 The gut microbiota of insects plays a vital role in digestion, nutrient acquisition, metabolism of dietary toxins, pathogen immunity and maintenance of gut homeostasis.
Yue Yin +6 more
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Mechanism of Gene Regulation by a
mBio, 2016 The virulence of many bacterial pathogens, including the important human pathogen Staphylococcus aureus, depends on the secretion of frequently large amounts of toxins. Toxin production involves the need for the bacteria to make physiological adjustments
Hwang-Soo Joo +8 more
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Molecular Insights into the Assembly and Functional Diversification of Typhoid Toxin
mBio, 2022 Typhoid toxin is an A2B5 protein toxin and an important virulence factor for the human-adapted bacterial pathogen Salmonella enterica serovar Typhi, the causative agent of typhoid fever. Typhoid toxin contains two enzymatic subunits, PltA and CdtB, which
Xiaoyu Liu +9 more
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Bacterial Toxins: Friends or Foes?
Emerging Infectious Diseases, 1999 Many emerging and reemerging bacterial pathogens synthesize toxins that serve as primary virulence factors. We highlight seven bacterial toxins produced by well-established or newly emergent pathogenic microbes.
Clare K. Schmitt +2 more
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BTXpred: Prediction of Bacterial Toxins
In Silico Biology: Journal of Biological Systems Modeling and Multi-Scale Simulation, 2007 This paper describes a method developed for predicting bacterial toxins from their amino acid sequences. All the modules, developed in this study, were trained and tested on a non-redundant dataset of 150 bacterial toxins that included 77 exotoxins and 73 endotoxins. Firstly, support vector machines (SVM) based modules were developed for predicting the
Sudipto Saha, Gajendra P. S. Raghava
openaire +3 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
A widespread family of polymorphic toxins encoded by temperate phages
BMC Biology, 2017 Background Polymorphic toxins (PTs) are multi-domain bacterial exotoxins belonging to distinct families that share common features in terms of domain organization.
Anne Jamet +7 more
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