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Carbohydrate inhibitors of cholera toxin [PDF]
Beilstein Journal of Organic Chemistry, 2018 Cholera is a diarrheal disease caused by a protein toxin released by Vibrio cholera in the host’s intestine. The toxin enters intestinal epithelial cells after binding to specific carbohydrates on the cell surface.
Bruce Turnbull, Vajinder Kumar
exaly +6 more sources
Advances in phage display based nano immunosensors for cholera toxin [PDF]
Frontiers in Immunology, 2023 Cholera, a persistent global public health concern, continues to cause outbreaks in approximately 30 countries and territories this year. The imperative to safeguard water sources and food from Vibrio cholerae, the causative pathogen, remains urgent. The
Yang Li +4 more
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Administration of novobiocin and apomorphine mitigates cholera toxin mediated cellular toxicity: Lessons from cholera toxin yeast model system. [PDF]
PLoS ONECholera is a dreadful disease. The scourge of this deadly disease is still evident in the developing world. Though several therapeutic strategies are in practice to combat and contain the disease, there is still a need for new drugs to control the ...
Sonali Eknath Bhalerao +2 more
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Vibrio mimicus Lineage Carrying Cholera Toxin and Vibrio Pathogenicity Island, United States and China [PDF]
Emerging Infectious DiseasesVibrio mimicus bacteria have caused sporadic cases and outbreaks of cholera-like diarrhea throughout the world, but the association of lineages with such events is unexplored. Genomic analyses revealed V.
Sergio Mascarenhas Morgado +3 more
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The Role of Vesicles in Transporting of Cholera Toxin
Проблемы особо опасных инфекций, 2023 The review reports on the secretion pathways of the main virulence factor of Vibrio cholerae, cholera toxin, both through the two-stage Sec-dependent type 2 secretion system and with the help of vesicles of the outer membrane of V. cholerae.
V. P. Zyuzina +4 more
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Проблемы особо опасных инфекций, 2022 A marker of the epidemic significance of Vibrio cholerae is their toxigenicity. Therefore, much attention is currently paid to the creation of diagnostic preparations for the detection of cholera toxin and assessment of the level of its production.
L. V. Larionova +4 more
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Vibrio cholerae Infection of Drosophilamelanogaster Mimics the Human Disease Cholera.
PLoS Pathogens, 2005 Cholera, the pandemic diarrheal disease caused by the gram-negative bacterium Vibrio cholerae, continues to be a major public health challenge in the developing world.
Nathan S Blow +6 more
doaj +2 more sources
OBTAINING OF MONOCLONAL ANTIBODIES AGAINST CHOLERA TOXIN AND HEAT LABILE ENTEROTOXIN OF E. coli FOR DEVELOPMENT OF THE TOXINS DIPLEX ANALYSIS IN ENVIRONMENTAL SPECIMENS [PDF]
Biotechnologia Acta, 2013 The present study focuses on development of monoclonal antibodies (MAbs) which specifically interact with cholera toxin or heat labile enterotoxin of E. coli.
Eu. V. Grishin, T. I. Valiakina
doaj +1 more source
Asian Pacific Journal of Tropical Biomedicine, 2017 Cholera is a well-known gastrointestinal infection. The cholera toxin is an important pathological substance in pathogenesis of cholera diarrhea. Cholera toxin is composed of catalytic A1 subunit, an A2 linker, and a homopentameric cell-binding B subunit.
Somsri Wiwanitkit, Viroj Wiwanitkit
doaj +1 more source
Neutralization of cholera toxin by Rosaceae family plant extracts
BMC Complementary and Alternative Medicine, 2019 Background Cholera is one of the most deadly diarrheal diseases that require new treatments. We investigated the neutralization of cholera toxin by five plant extracts obtained from the Rosaceae family that have been traditionally used in Poland to treat
Magdalena Komiazyk +4 more
doaj +1 more source