Results 11 to 20 of about 39,371 (175)
Impact of solar irradiation on cholera toxin secretion by different strains of Vibrio cholerae
South African Journal of Science, 2013 Cholera toxin is the aetiological agent of cholera – a deadly waterborne disease acquired through the consumption of untreated water contaminated with CTXФ bacteriophage harbouring strains of V. cholerae.
Cornelius C. Ssemakalu +2 more
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High-Resolution Crystal Structures Elucidate the Molecular Basis of Cholera Blood Group Dependence. [PDF]
PLoS Pathogens, 2016 Cholera is the prime example of blood-group-dependent diseases, with individuals of blood group O experiencing the most severe symptoms. The cholera toxin is the main suspect to cause this relationship. We report the high-resolution crystal structures (1.
Julie Elisabeth Heggelund +5 more
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New Microbes and New Infections, 2018 Cholera toxin (CT) is the principal virulence factor of Vibrio cholerae for fatal cholera diarrhoea. Serogroups O1 and O139 harbour CT and are known to be epidemic strains.
P. Kumar +8 more
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Проблемы особо опасных инфекций, 2015 Put forward is an efficient method for manufacturing cholera toxin B-subunit. Its advantages are relative simplicity and economy feasibility, as well as maximum output of the purified B-subunit, absolutely free from toxic A-subunit contaminant.
T. L. Zakharova +2 more
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Improvement of Technology of Cholera Toxin B-Subunit Production
Проблемы особо опасных инфекций, 2015 Consideration is given to implementation of state-of-the-art filtration technologies for up-scaled manufacturing of cholera toxin B-subunit, produced by recombinant Vibrio cholerae non O1 KM93 strain. Selected are micro- and ultra-filtration membranes to
A. V. Komissarov +8 more
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Production of putative enhanced oral cholera vaccine strains that express toxin-coregulated pilus. [PDF]
PLoS ONE, 2017 The use of whole cell killed (WCK) oral cholera vaccines is an important strategy for cholera prevention in endemic areas. To overcome current vaccine limitations, we engineered strains of V.
Caitlyn A Hauke, Ronald K Taylor
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p97 Is in a Complex with Cholera Toxin and Influences the Transport of Cholera Toxin and Related Toxins to the Cytoplasm [PDF]
Journal of Biological Chemistry, 2005 Certain protein toxins, including cholera toxin, ricin, and Pseudomonas aeruginosa exotoxin A, are transported to the lumen of the endoplasmic reticulum where they retro-translocate across the endoplasmic reticulum membrane to enter the cytoplasm.
Ramzey J, Abujarour +3 more
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Neutralization of cholera toxin with nanoparticle decoys for treatment of cholera. [PDF]
PLoS Neglected Tropical Diseases, 2018 Diarrheal diseases are a major cause of morbidity and mortality worldwide. In many cases, antibiotic therapy is either ineffective or not recommended due to concerns about emergence of resistance.
Soumita Das +7 more
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Conservation of cholera toxin gene in a strain of cholera toxin non-producing Vibrio cholerae O1 [PDF]
FEMS Microbiology Letters, 2006 BT23, a Vibrio cholerae O1 E1 Tor isolate, possesses the cholera toxin (CT) gene as determined by PCR. However, CT was not detected in the culture medium by the reversed passive latex agglutination test, nor in the whole cell lysate as examined by Western blotting. The toxin-coregulated pilus (TCP) was not detected by Western blotting.
Y, Honma, M, Iwanaga
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Bioscience Reports, 1977 Summary1. Death in several infectious diseases is caused by protein toxins secreted by invading bacteria. Cholera toxin is a simple protein secreted by Vibrio cholerae colonizing the gut; it is responsible for the massive diarrhoea that is cholera.2. The primary action of cholera toxin is an activation of adenylate cyclase, an enzyme found on the inner
openaire +3 more sources