Results 21 to 30 of about 41,359 (179)

Studies on Cholera Toxin and Antitoxin [PDF]

Journal of General Microbiology, 1970
SUMMARY: The preparation, purification and properties of cholera toxin type 2 are described. When the toxin was given to experimental animals it induced a high level of toxin-neutralizing antibodies. Cholera toxoid given to human volunteers induced antibodies consisting of agglutinins, vibriocidal and toxin-neutralizing antibodies.
J, Ungar, M, Stanić, N, Chariatte, S J, Varallyay   +3 more
openaire   +2 more sources

Phenotypic and Genetic Analysis of Altered Variants of Vibrio cholerae Biovar El Tor

Проблемы особо опасных инфекций, 2012
Determined is cholera toxin production by altered Vibrio cholerae O1 eltor strains, isolated on the territory of Russia in 1993-2010, which contain classical type ctxB gene.
S. P. Zadnova, A. V. Shashkova, Ya. M. Krasnov, N. I. Smirnova   +3 more
doaj   +1 more source

Enhanced sensitivity to cholera toxin in female ADP-ribosylarginine hydrolase (ARH1)-deficient mice.

PLoS ONE, 2018
Cholera toxin, an 84-kDa multimeric protein and a major virulence factor of Vibrio cholerae, uses the ADP-ribosyltransferase activity of its A subunit to intoxicate host cells.
Kizuku Watanabe, Jiro Kato, Jianfeng Zhu, Hirotake Oda, Hiroko Ishiwata-Endo, Joel Moss   +5 more
doaj   +1 more source

Removal of Cholera Toxin from Aqueous Solution by Probiotic Bacteria

Pharmaceuticals, 2012
Cholera remains a serious health problem, especially in developing countries where basic hygiene standards are not met. The symptoms of cholera are caused by cholera toxin, an enterotoxin, which is produced by the bacterium <em>Vibrio cholerae< ...
Jussi A. O. Meriluoto, Jari E. Heikkilä, Sonja M. K. Nybom, Seppo J. Salminen   +3 more
doaj   +1 more source

Effect of Dietary Minerals on Virulence Attributes of Vibrio cholerae

Frontiers in Microbiology, 2017
Vibrio cholerae is a water-borne pathogen responsible for causing a toxin-mediated profuse diarrhea in humans, leading to severe dehydration and death in unattended patients. With increasing reports of antibiotic resistance in V.
Varunkumar Bhattaram, Abhinav Upadhyay, Abhinav Upadhyay, Hsin-Bai Yin, Shankumar Mooyottu, Kumar Venkitanarayanan   +5 more
doaj   +1 more source

Microfluidic Engineering of Microgels: A Review of Emerging Technologies, Materials, Fabrication Strategies, and Applications

Advanced Healthcare Materials, EarlyView.
Recent advances in microfluidic technologies for microgel fabrication are critically reviewed, highlighting the capabilities and limitations of major microfluidic platforms and discussing how platform design, material selection, and crosslinking strategies influence microgel architecture and functionality. Current challenges and future opportunities in
Afshin Abrishamkar, Laura Neely, Cynthia Pham, Nada Ibrahim, Alexis Larios‐Cervantes, Ben A. Kertesz, Todd Hoare   +6 more
wiley   +1 more source

An Engineered HR1‐Stem Helix‐HR2 Trimeric Platform for Developing Broad‐Spectrum Coronavirus Vaccines

Advanced Science, EarlyView.
Sun et al. report a self‐assembling trimeric subunit vaccine platform termed RHS, which integrates the JN.1 receptor‐binding domain (RBD) with the heptad repeat 1 (HR1), stem helix (SH), and heptad repeat 2 (HR2) regions. The SARS‐CoV‐2 RHS vaccine elicits variant‐reactive RBD‐specific antibodies and cross‐reactive SH‐specific antibodies against ...
Xikui Sun, Junhao Fan, Xiaolu Xie, Yuting Shi, Xiaoqing Liu, Tiefeng Xu, Sidi Yang, Keda Shi, Chengshu Xie, Shixiong Li, Siwen Chen, Ruoxi Cai, Ping He, Yuzhen Ye, Tao Chen, Xiancai Ma, Chunmei Li, Jingyou Yu, Deyin Guo   +18 more
wiley   +1 more source

Chloroquine inhibition of cholera toxin [PDF]

FEBS Letters, 1990
Cholera toxin (CT) stimulated adenylate cyclase and a phospholipase which elevated levels of 3.5‐cyclic adenosine monophosphate (cAMP) and arachidonic acid (AA). The AA was quickly converted to prostaglandins (PGs) via the cyclo‐oxygenase pathway. Chloroquine exerted minimal inhibition of cAMP levels in CT‐treated cells, although CT‐induced release of [
Liang, Yi-fan, Peterson, Johnny W., Jackson, Christopher A., Reitmeyer, James C.   +3 more
openaire   +2 more sources

In Situ Photo‑Crosslinked Functional Bilayer Hydrogel Modulates Local Microenvironment and Remyelination After Optic Nerve Injury

Advanced Science, EarlyView.
A blue‐light‐crosslinked bilayer hydrogel was developed for local optic nerve repair. The adhesive GM‐Odex outer layer seals and anchors the lesion, while the non‐adhesive GM‐imid inner layer releases MPDA‐Cle without obstructing CSF flow. This system modulates oxidative and inflammatory microenvironments, supports oligodendrocyte differentiation and ...
Tonghe Pan, Yate Huang, Junhao Zhang, Shudong Tian, Zhixing Li, Xuanwen Li, Yanchen Zhang, Dongmei Wang, Sihao Ye, Ming Jin, Neng Ling, Wentao Yan, Kaihui Nan, Wencan Wu   +13 more
wiley   +1 more source

Construction of an El Tor Biovariant Vibrio cholerae Strain Capable of Type II Cholera Toxin Hyperproduction and Determining the Optimal Conditions for the Production of This Protein

Проблемы особо опасных инфекций, 2008
Introduction of Tn5-Mob (KmR) transposon into the chromosome of the toxinogenic V. cholerae strain MAK757 El Tor biovar was shown to result in the emergence of insertion mutants containing an altered genome of CTXφ prophage.
A. A. Goryaev, E. Yu. Shchelkanova, Yu. V. Lozovsky, I. V. Touchkov, N. I. Smirnova   +4 more
doaj   +1 more source