Results 41 to 50 of about 190,106 (220)

Studies on Cholera Toxin and Antitoxin [PDF]

open access: yesJournal of General Microbiology, 1970
SUMMARY: The preparation, purification and properties of cholera toxin type 2 are described. When the toxin was given to experimental animals it induced a high level of toxin-neutralizing antibodies. Cholera toxoid given to human volunteers induced antibodies consisting of agglutinins, vibriocidal and toxin-neutralizing antibodies.
J, Ungar   +3 more
openaire   +2 more sources

Phenotypic and Genetic Analysis of Altered Variants of Vibrio cholerae Biovar El Tor

open access: yesПроблемы особо опасных инфекций, 2012
Determined is cholera toxin production by altered Vibrio cholerae O1 eltor strains, isolated on the territory of Russia in 1993-2010, which contain classical type ctxB gene.
S. P. Zadnova   +3 more
doaj   +1 more source

Enhanced sensitivity to cholera toxin in female ADP-ribosylarginine hydrolase (ARH1)-deficient mice.

open access: yesPLoS ONE, 2018
Cholera toxin, an 84-kDa multimeric protein and a major virulence factor of Vibrio cholerae, uses the ADP-ribosyltransferase activity of its A subunit to intoxicate host cells.
Kizuku Watanabe   +5 more
doaj   +1 more source

Removal of Cholera Toxin from Aqueous Solution by Probiotic Bacteria

open access: yesPharmaceuticals, 2012
Cholera remains a serious health problem, especially in developing countries where basic hygiene standards are not met. The symptoms of cholera are caused by cholera toxin, an enterotoxin, which is produced by the bacterium <em>Vibrio cholerae< ...
Jussi A. O. Meriluoto   +3 more
doaj   +1 more source

Effect of Dietary Minerals on Virulence Attributes of Vibrio cholerae

open access: yesFrontiers in Microbiology, 2017
Vibrio cholerae is a water-borne pathogen responsible for causing a toxin-mediated profuse diarrhea in humans, leading to severe dehydration and death in unattended patients. With increasing reports of antibiotic resistance in V.
Varunkumar Bhattaram   +5 more
doaj   +1 more source

ANXA2+ Small Extracellular Vesicles Drive Chemoresistance in Anaplastic Thyroid Cancer by Promoting XRCC5 Lactylation and Enhancing Non‐Homologous End‐Joining Repair

open access: yesAdvanced Science, EarlyView.
ANXA2+ sEVs promote cisplatin resistance in ATC by stabilizing the SRC/LDHA interaction, increasing LDHA phosphorylation and activity, and lactate production. Elevated lactate levels promote KAT5‐mediated lactylation of XRCC5 at lysine 265, enhancing its binding to XRCC6.
Shanshan Su   +4 more
wiley   +1 more source

Therapeutic dendritic cell vaccination against human papillomavirus [PDF]

open access: yes, 2009
Cervical cancer, which is caused by infection with human papillomavirus (HPV), is the second most common cancer among women worldwide, leading to 230000 deaths annually.
Nurkkala Karlsson, Merja
core   +1 more source

Chloroquine inhibition of cholera toxin [PDF]

open access: yesFEBS Letters, 1990
Cholera toxin (CT) stimulated adenylate cyclase and a phospholipase which elevated levels of 3.5‐cyclic adenosine monophosphate (cAMP) and arachidonic acid (AA). The AA was quickly converted to prostaglandins (PGs) via the cyclo‐oxygenase pathway. Chloroquine exerted minimal inhibition of cAMP levels in CT‐treated cells, although CT‐induced release of [
Liang, Yi-fan   +3 more
openaire   +2 more sources

An Engineered HR1‐Stem Helix‐HR2 Trimeric Platform for Developing Broad‐Spectrum Coronavirus Vaccines

open access: yesAdvanced Science, EarlyView.
Sun et al. report a self‐assembling trimeric subunit vaccine platform termed RHS, which integrates the JN.1 receptor‐binding domain (RBD) with the heptad repeat 1 (HR1), stem helix (SH), and heptad repeat 2 (HR2) regions. The SARS‐CoV‐2 RHS vaccine elicits variant‐reactive RBD‐specific antibodies and cross‐reactive SH‐specific antibodies against ...
Xikui Sun   +18 more
wiley   +1 more source

Mechanism of action of cholera toxin [PDF]

open access: yes, 1980
Cholera toxin, obtained as crude culture filtrates of the bacterium Vibrio cholerae, was purified by a combination of ammonium sulphate fractionation, ion-exchange chromatography on DEAE-cellulose, and gel filtration cn Ultrogel AcA-44.
Tait, R.M.
core   +2 more sources

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