Results 41 to 50 of about 190,106 (220)
Studies on Cholera Toxin and Antitoxin [PDF]
SUMMARY: The preparation, purification and properties of cholera toxin type 2 are described. When the toxin was given to experimental animals it induced a high level of toxin-neutralizing antibodies. Cholera toxoid given to human volunteers induced antibodies consisting of agglutinins, vibriocidal and toxin-neutralizing antibodies.
J, Ungar +3 more
openaire +2 more sources
Phenotypic and Genetic Analysis of Altered Variants of Vibrio cholerae Biovar El Tor
Determined is cholera toxin production by altered Vibrio cholerae O1 eltor strains, isolated on the territory of Russia in 1993-2010, which contain classical type ctxB gene.
S. P. Zadnova +3 more
doaj +1 more source
Enhanced sensitivity to cholera toxin in female ADP-ribosylarginine hydrolase (ARH1)-deficient mice.
Cholera toxin, an 84-kDa multimeric protein and a major virulence factor of Vibrio cholerae, uses the ADP-ribosyltransferase activity of its A subunit to intoxicate host cells.
Kizuku Watanabe +5 more
doaj +1 more source
Removal of Cholera Toxin from Aqueous Solution by Probiotic Bacteria
Cholera remains a serious health problem, especially in developing countries where basic hygiene standards are not met. The symptoms of cholera are caused by cholera toxin, an enterotoxin, which is produced by the bacterium <em>Vibrio cholerae< ...
Jussi A. O. Meriluoto +3 more
doaj +1 more source
Effect of Dietary Minerals on Virulence Attributes of Vibrio cholerae
Vibrio cholerae is a water-borne pathogen responsible for causing a toxin-mediated profuse diarrhea in humans, leading to severe dehydration and death in unattended patients. With increasing reports of antibiotic resistance in V.
Varunkumar Bhattaram +5 more
doaj +1 more source
ANXA2+ sEVs promote cisplatin resistance in ATC by stabilizing the SRC/LDHA interaction, increasing LDHA phosphorylation and activity, and lactate production. Elevated lactate levels promote KAT5‐mediated lactylation of XRCC5 at lysine 265, enhancing its binding to XRCC6.
Shanshan Su +4 more
wiley +1 more source
Therapeutic dendritic cell vaccination against human papillomavirus [PDF]
Cervical cancer, which is caused by infection with human papillomavirus (HPV), is the second most common cancer among women worldwide, leading to 230000 deaths annually.
Nurkkala Karlsson, Merja
core +1 more source
Chloroquine inhibition of cholera toxin [PDF]
Cholera toxin (CT) stimulated adenylate cyclase and a phospholipase which elevated levels of 3.5‐cyclic adenosine monophosphate (cAMP) and arachidonic acid (AA). The AA was quickly converted to prostaglandins (PGs) via the cyclo‐oxygenase pathway. Chloroquine exerted minimal inhibition of cAMP levels in CT‐treated cells, although CT‐induced release of [
Liang, Yi-fan +3 more
openaire +2 more sources
Sun et al. report a self‐assembling trimeric subunit vaccine platform termed RHS, which integrates the JN.1 receptor‐binding domain (RBD) with the heptad repeat 1 (HR1), stem helix (SH), and heptad repeat 2 (HR2) regions. The SARS‐CoV‐2 RHS vaccine elicits variant‐reactive RBD‐specific antibodies and cross‐reactive SH‐specific antibodies against ...
Xikui Sun +18 more
wiley +1 more source
Mechanism of action of cholera toxin [PDF]
Cholera toxin, obtained as crude culture filtrates of the bacterium Vibrio cholerae, was purified by a combination of ammonium sulphate fractionation, ion-exchange chromatography on DEAE-cellulose, and gel filtration cn Ultrogel AcA-44.
Tait, R.M.
core +2 more sources

