Results 51 to 60 of about 45,647 (229)
INTERACTION OF CHOLERA TOXIN AND TOXIN DERIVATIVES WITH LYMPHOCYTES [PDF]
The Journal of Experimental Medicine, 1974 The interaction of cholera toxin and a number of toxin derivatives, containing different proportions of light and heavy toxin-composing subunits (L and H), with mouse lymphocytes was studied. Experiments with [125I]toxin showed that a single cell can rapidly, within minutes, bind up to 40,000 molecules of toxin, the association constant was estimated ...
Stefan Lange +2 more
openaire +1 more source
Plant Virus Immunotherapy for HPV‐Associated Oropharyngeal Squamous Cell Carcinoma
Advanced NanoBiomed Research, EarlyView.Cowpea mosaic virus (CPMV) nanoparticles are safe and potent cancer immunotherapy candidates with strong immunomodulatory activity. CPMV activates innate immunity, which in turn drives adaptive immune responses and promotes durable, systemic antitumor effects.
Jessica Fernanda Affonso de Oliveira +7 more
wiley +1 more source
Cholera toxin gene-positive Vibrio cholerae O1 Ogawa and Inaba strains produce the new cholera toxin
, 1988 Two strains of cholera toxin (CT) gene-positive Vibrio cholerae O1, Ogawa, isolated from patients with diarrhoea and the hypertoxigenic V. cholerae O1, Inaba (569B), were found to produce the new cholera toxin that has earlier been demonstrated to be ...
Saha, Setarunnahar, Sanyal, S. C.
core +1 more source
The Iraqi Journal of Veterinary Medicine, 2010 Fifty isolates of Vibrio cholerae obtained from different areas in Iraq from patients with acute secretory diarrhea were diagnosed serologically in central public health laboratory(CPHL), Two different methods were used for detection cholera toxin ...
Atheer Abdulrazzaq
doaj +1 more source
Vibrio Pathogenicity Island-1: The Master Determinant of Cholera Pathogenesis
Frontiers in Cellular and Infection Microbiology, 2020 Cholera is an acute secretory diarrhoeal disease caused by the bacterium Vibrio cholerae. The key determinants of cholera pathogenicity, cholera toxin (CT), and toxin co-regulated pilus (TCP) are part of the genome of two horizontally acquired Mobile ...
Ashok Kumar +5 more
doaj +1 more source
Grape extracts inhibit multiple events in the cell biology of cholera intoxication. [PDF]
PLoS ONE, 2013 Vibrio cholerae produces cholera toxin (CT), an AB5 protein toxin that is primarily responsible for the profuse watery diarrhea of cholera. CT is secreted into the extracellular milieu, but the toxin attacks its Gsα target within the cytosol of a host ...
Srikar Reddy +7 more
doaj +1 more source
Molecules, 2023 Cholera is an exceptionally aggressive infectious disease characterized by the potential to induce acute, copious, watery diarrhea of considerable severity and renal inflammation.
Mahmoud Dahab +3 more
doaj +1 more source
Actions of cholera toxin and the prevention and treatment of cholera [PDF]
Nature, 1981 The drastic intestinal secretion of fluid and electrolytes that is characteristic of cholera is the result of reasonably well understood cellular and biochemical actions of the toxin secreted by Vibrio cholerae. Based on this understanding it is possible to devise new techniques for the treatment and prophylaxis of cholera to complement those based on ...
openaire +2 more sources
Subunit Structure of Cholera Toxin [PDF]
Journal of General Microbiology, 1973 SUMMARY Two types of subunit, with molecular weights estimated to be 28000 and 8000, were demonstrated in the cholera exo-enterotoxin by sodium dodecylsulphate polyacrylamide electrophoresis. The light (L) component but not the heavy (H) was demonstrable in the antigenically identical natural toxoid.
I, Lönnroth, J, Holmgren
openaire +2 more sources
Advanced NanoBiomed Research, EarlyView.We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer +5 more
wiley +1 more source