Results 71 to 80 of about 72,576 (226)
Fifty isolates of Vibrio cholerae obtained from different areas in Iraq from patients with acute secretory diarrhea were diagnosed serologically in central public health laboratory(CPHL), Two different methods were used for detection cholera toxin ...
Atheer Abdulrazzaq
doaj +1 more source
Vibrio Pathogenicity Island-1: The Master Determinant of Cholera Pathogenesis
Cholera is an acute secretory diarrhoeal disease caused by the bacterium Vibrio cholerae. The key determinants of cholera pathogenicity, cholera toxin (CT), and toxin co-regulated pilus (TCP) are part of the genome of two horizontally acquired Mobile ...
Ashok Kumar +5 more
doaj +1 more source
Grape extracts inhibit multiple events in the cell biology of cholera intoxication. [PDF]
Vibrio cholerae produces cholera toxin (CT), an AB5 protein toxin that is primarily responsible for the profuse watery diarrhea of cholera. CT is secreted into the extracellular milieu, but the toxin attacks its Gsα target within the cytosol of a host ...
Srikar Reddy +7 more
doaj +1 more source
Cholera is an exceptionally aggressive infectious disease characterized by the potential to induce acute, copious, watery diarrhea of considerable severity and renal inflammation.
Mahmoud Dahab +3 more
doaj +1 more source
Gz, a guanine nucleotide-binding protein with unique biochemical properties [PDF]
Cloning of a complementary DNA (cDNA) for Gz alpha, a newly appreciated member of the family of guanine nucleotide-binding regulatory proteins (G proteins), has allowed preparation of specific antisera to identify the protein in tissues and to assay it ...
Casey, Patrick J. +3 more
core
Vietnam currently produces an orally administered, bivalent (O1 and O139) killed whole-cell vaccine and is the only country in the world with endemic cholera to use an oral cholera vaccine in public health practice.
Anh, Dang Duc +13 more
core +1 more source
We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer +5 more
wiley +1 more source
El Tor biotype Vibrio cholerae activates the caspase-11-independent canonical Nlrp3 and Pyrin inflammasomes [PDF]
Vibrio cholerae is a Gram-negative enteropathogen causing potentially life-threatening cholera disease outbreaks, for which the World Health Organization currently registers 2-4 million cases and similar to 100.000 cholera-associated deaths annually ...
Asaoka, Tomoko +5 more
core +1 more source
Cholera toxin: Vibrio cholera's dehydration machine
The Blue Valley Center for Advanced Professional Studies (BVCAPS) SMART Team members researched the actions of the microbe Vibrio cholera in causing the water born disease cholera, which infects millions of humans annually and causes death to thousands of individuals through extreme fluid ...
C. Anderson +31 more
openaire +1 more source
Structural inferences for Cholera toxin mutations in Vibrio cholerae [PDF]
Cholera is a global disease that has persisted for millennia. The cholera toxin (CT) from Vibrio cholerae is responsible for the clinical symptoms of cholera. This toxin is a hetero-hexamer (AB(5)) complex consisting of a subunit A (CTA) with a pentamer (B(5)) of subunit B (CTB).
Gunasagaran, Shamini +6 more
openaire +2 more sources

