Results 81 to 90 of about 45,647 (229)

RAB4A acts as a negative feedback regulator of extracellular vesicle secretion during TGF‐β signaling

open access: yesThe FEBS Journal, EarlyView.
TGF‐β signaling regulates extracellular vesicle (EV) release in cancer cells by modulating the expression and activity of genes associated with EV biogenesis. The TGF‐β‐induced upregulation of RAB4A expression facilitates fast endosomal recycling, a process that limits the fusion of multivesicular bodies with the plasma membrane and EV secretion. Hence,
Dorival Mendes Rodrigues‐Junior   +5 more
wiley   +1 more source

Expression of cholera toxin B subunit in Saccharomyces cerevisiae [PDF]

open access: yes
Cholera toxin, secreted by Vibrio cholerae, consists of A and B subunits. Cholera toxin B subunit (CTB) is used in many scientific research. It has already been expressed in several bacterial and plant systems.
ارزنلو, محسن   +6 more
core  

The Apoptotic Effects of the P300 Activator on Breast Cancer and Lung Fibroblast Cell Lines

open access: yesMiddle East Journal of Cancer, 2013
Background: P300 is an enzyme that acetylates histones during stress. It alsoacetylates several non-histone proteins, including P53 which is the most important tumorsuppressor gene. P53 plays an important role in the apoptosis of tumor cells. Hereby,this
Mohammad Reza Salahshoor   +5 more
doaj  

The MacBrain Resource Center (MBRC) rhesus macaque postnatal brain histology datasets: Enabling new discoveries through NHP tissue and digital data Repositories

open access: yesJournal of Anatomy, EarlyView.
The MacBrain Resource Center (MBRC) postnatal rhesus macaque brain histology datasets are organized into Collections that promote cost‐effective de novo research. This article provides examples from Collections 5, 6, and 7 and describes the histo‐ and immunohistochemical (IHC) processing of materials for Collection 6.
Valeria Mendoza‐Silva   +19 more
wiley   +1 more source

Mechanism of action of cholera toxin [PDF]

open access: yes, 1982
Cholera "toxin binds to the outside of cells and one of its sub-units enters to activate adenylate cyclase. In the current work the nature of this action across the membrane was related to the hydrophobicities of cholera toxin and its subunits. Charge—
Ward, W.H.J
core  

Integration of cortical inputs in the lateral hypothalamus is dominated by the medial prefrontal cortex

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The lateral hypothalamus (LH) is a critical controller of innate behaviours such as feeding. It is anatomically connected to specific cortical areas. We mapped these areas using a combination of retrograde tracing and anterograde optogenetic circuit mapping.
Lotte J. A. M. Razenberg   +3 more
wiley   +1 more source

THE STUDY OF LYMPHOCYTE APOPTOSIS INDUCED BY VIBRIO CHOLERAE ANTIGENS IN THE FORMATION OF IMMUNODEFICIENCY AND THE POSSIBILITY OF ITS CORRECTION

open access: yesМедицинский вестник Юга России, 2013
Purpose: To study the role of lymphocyte apoptosis induced by Vibrio cholerae microbial cells and cholera toxin in the formation of the postvaccinal apoptotic immunodeficiency, as well as the possibility of its correction with the use of immunomodulator ...
I. A. Ivanova   +9 more
doaj   +1 more source

Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry

open access: yesMass Spectrometry Reviews, Volume 45, Issue 4, Page 800-828, July/August 2026.
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui   +4 more
wiley   +1 more source

Association between post-diagnostic use of cholera vaccine and risk of death in prostate cancer patients

open access: yesNature Communications, 2018
Post-diagnostic use of cholera vaccine can improve the prognosis in patients with colorectal cancer suggesting cholera toxin might have an antineoplastic effect.
Jianguang Ji   +2 more
doaj   +1 more source

Posttranslational Regulation of IL-23 Production Distinguishes the Innate Immune Responses to Live Toxigenic versus Heat-Inactivated Vibrio cholerae

open access: yesmSphere, 2019
Vibrio cholerae infection provides long-lasting protective immunity, while oral, inactivated cholera vaccines (OCV) result in more-limited protection. To identify characteristics of the innate immune response that may distinguish natural V.
Ana A. Weil   +13 more
doaj   +1 more source

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