Results 81 to 90 of about 190,106 (220)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, Volume 16, Issue 9, Page 1691-1707, September 2026.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Nanomaterial Strategies for Pulmonary Delivery of Immunotherapeutics in Lung Cancer Treatment

Advanced Healthcare Materials, Volume 15, Issue 34, 11 September 2026.
Inhalable immunotherapeutic nanomedicines enable organ‐selective immune modulation by overcoming pulmonary delivery barriers and concentrating therapy within lung tumors. This Review defines how nanomaterial properties govern airway deposition, retention, cellular partitioning, and immune activation across vaccines, checkpoint blockade, STING agonists,
Han Zhang, Wei Tang
wiley   +1 more source

Cellularized Skin Substitute Bioengineering for Regenerative Medicine: Cell Sources, Culture Strategies, and Transition Toward Defined, Xeno‐Free Culture Systems

Advanced Healthcare Materials, Volume 15, Issue 34, 11 September 2026.
Advances in cell sources, bioengineering, and manufacturing are reshaping the design of skin substitutes. This review highlights emerging strategies driving skin tissue engineering and discusses their potential to enable safer, reproducible, and clinically accessible skin substitutes for regenerative medicine.
Gilles Lemaître, Marina Trouillas, Tatiana Vinasco‐Sandoval, Cécile Giordano, Alexandre G. Lellouch, Walid Rachidi, Jean‐Jacques Lataillade, Nicolas O. Fortunel   +7 more
wiley   +1 more source

Improving community coverage of oral cholera mass vaccination campaigns: lessons learned in Zanzibar [PDF]

, 2012
BACKGROUND: Recent research in two cholera-endemic communities of Zanzibar has shown that a majority (?94%) of the adult population was willing to receive free oral cholera vaccines (OCVs). Since OCV uptake in the 2009 campaign reached only ?50% in these
Claire-Lise Chaignat, Weiss Mitchell G., Schaetti, C., Weiss, M. G., Khatib, A. M., Ahmed M. Khatib (130136), Said M. Ali, Mitchell G Weiss, Hutubessy Raymond, Schaetti Christian, Ahmed M Khatib, Claire-Lise Chaignat (127845), Raymond Hutubessy (130149), Ali, S. M., Khatib Ahmed M., Mitchell G. Weiss, Mitchell G. Weiss (130129), Ahmed M. Khatib, Chaignat Claire-Lise, Ali Said M., Hutubessy, R., Christian Schaetti (130127), Chaignat, C. L., Raymond Hutubessy, Christian Schaetti, Said M Ali, Said M. Ali (130132)   +26 more
core   +1 more source

Membrane Fusion‐Mediated Cytosolic Delivery of Threose Nucleic Acids via Homotypic Nanoparticles Overcomes Drug Resistance in Triple‐Negative Breast Cancer

Advanced Science, Volume 13, Issue 50, 7 September 2026.
This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng, Tristan Juin Han Chang, Xinchao Li, Zhongqi Zhou, Chung Tin, Kenward Vong, Pierre Karam, Pik Kwan Lo   +7 more
wiley   +1 more source

Curing Cholera: Pathogens, Places and Poverty in South Asia [PDF]

, 2010
In this paper I will seek to provide a new understanding of endemicity of disease in India. Through a study of cholera research in the twentieth century I will argue that disease and its endemicity has to be understood in biological factors as well as ...
Chakrabarti, Pratik
core  

Cholera outbreak in southern Tanzania: risk factors and patterns of transmission. [PDF]

, 2001
To identify risk factors and describe the pattern of spread of the 1997 cholera epidemic in a rural area (Ifakara) in southern Tanzania, we conducted a prospective hospital-based, matched case- control study, with analysis based on the first 180 cases ...
Jordi Vila, Pedro L. Alonso, Casals, C, Urassa, H, Alonso, P L, Marcel Tanner, Fred Lwilla, Manuel Corachán, Camilo J. Acosta, Hassan Mshinda, Claudia M. Galindo, Galindo, C M, Acosta, C J, Honorathy Urassa, Kesheni Senkoro, Kimario, J, John Kimario, Acosta, CJ, N. Eseko, Vila, J, Mshinda, H, Eseko, N, Tanner, M, Alonso, PL, Climent Casals, Senkoro, K, Corachán, M, Lwilla, F, Galindo, CM, Corachán Cuyás, Manuel, Casals Pascual, Climent, Urassa, Honorathy, Vila Estapé, Jordi, Senkoro, Kesheni, Mshinda, Hassan, Tanner, Marcel, Alonso, Pedro, Galindo, Claudia M., Acosta, Camilo J., Kimario, John, Eseko, N., Lwilla, Fred   +41 more
core   +1 more source

From Sourcing to End‐of‐Life: Sustainability Challenges and Opportunities in Organic Bioelectronics

Advanced Science, Volume 13, Issue 51, 14 September 2026.
Organic bioelectronics bridges biology and electronics using organic mixed ionic/electronic conductors. This Perspective addresses sustainability across the full lifecycle of organic bioelectronic materials and devices, offering a framework to guide material sourcing, synthesis, fabrication, application, and end‐of‐life strategies toward bioelectronic ...
Gwennaël Dufil, Marine Batista, Andrea Bionda, Erica Zeglio   +3 more
wiley   +1 more source

Expression of cholera toxin B subunit in Saccharomyces cerevisiae [PDF]

Cholera toxin, secreted by Vibrio cholerae, consists of A and B subunits. Cholera toxin B subunit (CTB) is used in many scientific research. It has already been expressed in several bacterial and plant systems.
ارزنلو, محسن, آهنگرزاده رضایی, محمد, زواران حسینی, احمد, توچیکوبو, کونیو, شاهرخی, نادر, یاسودا, یوکو, رضایی, عباس   +6 more
core  

Eriosema glomeratum Possessed Interesting Bioactive Constituents and Semisynthetic Derivatives With Relevant Biosynthetic Correlation and Important Chemophenetic Significance

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
A medicinal plant Eriosema glomeratum has potentially lead compounds, erioschalcones A and B, and their semisynthetic derivatives for drug discovery. ABSTRACT Plants are sources of compounds with benefits in human health and animal well‐being. Plant‐based foods may contain huge numbers of different phytochemicals.
Gaétan Tchangou Tabakam, Maurice Ducret Awouafack   +1 more
wiley   +1 more source