Results 101 to 110 of about 45,647 (229)

Biomarkers of Environmental Enteropathy are Positively Associated with Immune Responses to an Oral Cholera Vaccine in Bangladeshi Children.

PLoS Neglected Tropical Diseases, 2016
Environmental enteropathy (EE) is a poorly understood condition that refers to chronic alterations in intestinal permeability, absorption, and inflammation, which mainly affects young children in resource-limited settings. Recently, EE has been linked to
Muhammad Ikhtear Uddin, Shahidul Islam, Naoshin S Nishat, Motaher Hossain, Tanzeem Ahmed Rafique, Rasheduzzaman Rashu, Mohammad Rubel Hoq, Yue Zhang, Amit Saha, Jason B Harris, Stephen B Calderwood, Taufiqur Rahman Bhuiyan, Edward T Ryan, Daniel T Leung, Firdausi Qadri   +14 more
doaj   +1 more source

Back to the Future: Studying Cholera Pathogenesis Using Infant Rabbits

mBio, 2010
Cholera is a severe diarrheal disease, caused by Vibrio cholerae, for which there has been no reproducible, nonsurgical animal model. Here, we report that orogastric inoculation of V.
Jennifer M. Ritchie, Haopeng Rui, Roderick T. Bronson, Matthew K. Waldor   +3 more
doaj   +1 more source

The Protein Phosphatase Inhibitor LB100 Targets the Mesenchymal Lineage of Pancreatic Ductal Adenocarcinoma

MedComm, Volume 7, Issue 6, June 2026.
To define the mechanisms of sensitivity to PP2A inhibitors (PP2Ai), we combined molecular profiling of PP2Ai responses with genome‐wide genetic screens. PP2Ai preferentially target mesenchymal pancreatic ductal adenocarcinoma (PDAC) cells and engage pathways linked to transcriptional elongation, splicing, metabolism, and ER stress response factors ...
Janine Murr, Carolin Schneider, Ningjun Duan, Hazal Köse, Anantharamanan Rajamani, Xueyang He, Jonas Buchloh, Christian Hintze, Atharva Naik, Daniel Goeke, Nicole Rjasanow, Lukas Krauß, Alexandra Nguyen, Sebastian A. Widholz, Christian Schneeweis, Riccardo Trozzo, Felix Orben, Sebastian Mueller, Rupert Öllinger, Juan J Montero, Michael Dudek, Percy Knolle, Bo Kong, Volker Ellenrieder, Constanza Tapia Contreras, Elisabeth Hessmann, Marian Grade, Michael Ghadimi, Christian J. Braun, Roland Rad, Maximillian Reichert, Ulrich Keller, Roland M. Schmid, Paul L. Boutz, Dieter Saur, Matthias Wirth, Oliver H. Krämer, Günter Schneider   +37 more
wiley   +1 more source

ROLE OF CHOLERA TOXIN IN EXPERIMENTAL CHOLERA [PDF]

Journal of Bacteriology, 1959
N K, DUTTA, M V, PANSE, D R, KULKARNI
openaire   +2 more sources

When Public Health Becomes the Weapon: Current and Prospective Consequences of the Genocide in Gaza

World Medical &Health Policy, Volume 18, Issue 2, June 2026.
ABSTRACT Catastrophic humanitarian conditions during the 2023–2025 genocide in Gaza have caused a public health crisis of exceptional magnitude. This article summarizes key short‐ and long‐term health consequences for Gaza's civilian population and outlines priorities for recovery.
Therese Alexandra Evald, Nanna Gram Ahlmark, Clara Barfod Parellada, Andreea Micula, Caroline Klint Johannesen, Dana Bdier, Fayez Mahamid, Hilde Lausund, Jane Brandt Sørensen, Maha Aon, Majd Qannita, Maren Johanne Heilskov Rytter, Nanna Maaløe, Nina Jøranson, Sara Aakre Faradonbeh, Vibeke Brix Christensen, Waseem Alzaanin, Sigurd Lauridsen, Helle Timm, Frederik Schou‐Juul   +19 more
wiley   +1 more source

PENGARUH EKSTRAK DIKLOROMETAN JAHE (Zingiber officinale Roscoe) TERHADAP PENGIKATAN TOKSIN KOLERA B-subunit CONJUGASI (FITC) PADA RECEPTOR SEL HIBRIDOMA LV DAN CACO-2 [Effect of Ginger (Zingiber officinale Roscoe) Dichloromethane Extract on Inhibition of Cholera Toxin B-subunit Conjugated FITC Binding to Receptor on LV Hibridome and Caco-2 Cells]

Jurnal Teknologi dan Industri Pangan, 2003
Cholera toxin is main factor that responsibility of watery diarrhea. The objectives of this investigation was to study the effect of ginger extract (GDE) in blocking cholera toxin binding to receptors of LV hybridome and Caco-2 cells.Analysis of toxin
Radiati, L.E 1), Nabet, P , Franck, P 2), Nabet B 2), Capiaumont, J 2), Fardiaz, D 3), Zakaria, R.F 3), I. Sudirman 4), Hariyadi, R.D 3)   +7 more
doaj  

In-silico identification of anti-cholera phytochemicals from Indian medicinal plants.

PLoS ONE
Cholera is a severe diarrheal disease caused by ingestion of food or water contaminated with pathogenic Vibrio cholerae. Treatment for cholera includes rehydration therapy and antibiotics to avert death and reduce bacterial burden to prevent rapid ...
Khalilur Rahman, Yasmin Akter, Md Selim Reza, Md Al Amin Pappu, Md Rezaul Karim, Marzia Sultana, Mohammad Tarequl Islam, Munirul Alam, Md Nurul Haque Mollah, Md Mamun Monir   +9 more
doaj   +1 more source

Molecular Dynamics Simulation of Cholera Toxin A-1 Polypeptide

Open Chemistry, 2016
A molecular dynamics (MD) simulation study of the enzymatic portion of cholera toxin; cholera toxin A-1 polypeptide (CTA1) was performed at 283, 310 and 323 K.
Badshah Syed Lal, Khan Abdul Naeem, Mabkhot Yahia Nasser   +2 more
doaj   +1 more source

A Modular Design of a Cholera Toxin B Subunit‐Scaffolded Sub‐Virion Nanoparticle Vaccine Against West Nile Virus

Microbial Biotechnology, Volume 19, Issue 6, June 2026.
A recombinant West Nile virus (WNV) subunit vaccine was developed by displaying ED3 on a CTB scaffold. The fusion protein formed soluble nanoparticles in E. coli, eliciting strong, balanced, and specific neutralizing antibodies without cross‐reactivity, offering a safe, scalable subunit vaccine platform.
Hyun Byun, Tae Hoon Kim, Jemin Sung, Jung‐Min Lee, Sang‐Mu Shim, Sin Hae Kang, Hanul Kang, Dah Hyun Moon, Seong Hyun Park, Doda Kim, Sung Jae Kim, Seunghoo Kim, Gyoonhee Han, Baik Lin Seong   +13 more
wiley   +1 more source

The cytosolic fate of ricin A chain in target cells [PDF]

Ricin is a heterodimeric, toxic plant protein. It is able to deliver its catalytic A chain (RTA) into the cytosol of target cells. RTA crosses the endoplasmic reticulum (ER) membrane into the cytosol, masquerading as a substrate of ER-associated ...
Hart, Philip John
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