Results 111 to 120 of about 72,576 (226)

Pandemic Vibrio cholerae and the Environmental Reservoir Hypothesis—Outstanding Questions Central to Global Cholera Control

Environmental Microbiology, Volume 28, Issue 5, May 2026.
Whether, when and for how long pandemic Vibrio cholerae forms long‐term environmental reservoirs remains uncertain. We propose a new framework to evaluate possible mechanisms by which the pathogen might experience reservoir formation versus environmental elimination.
Azfar D. Hossain, William P. Robins, John J. Mekalanos, Louise C. Ivers   +3 more
wiley   +1 more source

Mixed Signals: T Cells as Architects of IgE Immunity

Immunological Reviews, Volume 339, Issue 1, May 2026.
ABSTRACT Food allergen‐specific IgE can cause significant pathology, yet the pathways that generate pathogenic, high‐affinity IgE remain incompletely understood. Increasing evidence suggests that IgE responses arise from the integration of multiple, and sometimes opposing, T cell–derived cues.
Abigail L. Tierney, Wallace P. Bezerra, Stephanie C. Eisenbarth, Adam Williams   +3 more
wiley   +1 more source

PENGARUH EKSTRAK DIKLOROMETAN JAHE (Zingiber officinale Roscoe) TERHADAP PENGIKATAN TOKSIN KOLERA B-subunit CONJUGASI (FITC) PADA RECEPTOR SEL HIBRIDOMA LV DAN CACO-2 [Effect of Ginger (Zingiber officinale Roscoe) Dichloromethane Extract on Inhibition of Cholera Toxin B-subunit Conjugated FITC Binding to Receptor on LV Hibridome and Caco-2 Cells]

Jurnal Teknologi dan Industri Pangan, 2003
Cholera toxin is main factor that responsibility of watery diarrhea. The objectives of this investigation was to study the effect of ginger extract (GDE) in blocking cholera toxin binding to receptors of LV hybridome and Caco-2 cells.Analysis of toxin
Radiati, L.E 1), Nabet, P , Franck, P 2), Nabet B 2), Capiaumont, J 2), Fardiaz, D 3), Zakaria, R.F 3), I. Sudirman 4), Hariyadi, R.D 3)   +7 more
doaj  

In-silico identification of anti-cholera phytochemicals from Indian medicinal plants.

PLoS ONE
Cholera is a severe diarrheal disease caused by ingestion of food or water contaminated with pathogenic Vibrio cholerae. Treatment for cholera includes rehydration therapy and antibiotics to avert death and reduce bacterial burden to prevent rapid ...
Khalilur Rahman, Yasmin Akter, Md Selim Reza, Md Al Amin Pappu, Md Rezaul Karim, Marzia Sultana, Mohammad Tarequl Islam, Munirul Alam, Md Nurul Haque Mollah, Md Mamun Monir   +9 more
doaj   +1 more source

In Vitro Selection of a Single-Stranded DNA Molecular Recognition Element against Clostridium difficile Toxin B and Sensitive Detection in Human Fecal Matter

Journal of Nucleic Acids, 2015
Toxin B is one of the major virulence factors of Clostridium difficile, a bacterium that is responsible for a significant number of diarrhea cases in acute care settings. Due to the prevalence of C. difficile induced diarrhea, rapid and correct diagnosis
Ka Lok Hong, Eamonn Maher, Ryan M. Williams, Letha J. Sooter   +3 more
doaj   +1 more source

Engineering Marker‐Free Lettuce Chloroplast Genome to Express Functional Glucagon‐Like Peptide‐1 Receptor Agonists Exenatide and Lixisenatide

Plant Biotechnology Journal, Volume 24, Issue 5, Page 3158-3171, May 2026.
Engineering of marker‐free lettuce chloroplast genome to express CTB‐Exenatide and CTB‐Lixisenatide for oral delivery. Upper panel: Chemically synthesised exenatide or lixisenatide require expensive production, purification, refrigeration and invasive delivery methods.
Rahul Singh, Henry Daniell
wiley   +1 more source

Molecular Dynamics Simulation of Cholera Toxin A-1 Polypeptide

Open Chemistry, 2016
A molecular dynamics (MD) simulation study of the enzymatic portion of cholera toxin; cholera toxin A-1 polypeptide (CTA1) was performed at 283, 310 and 323 K.
Badshah Syed Lal, Khan Abdul Naeem, Mabkhot Yahia Nasser   +2 more
doaj   +1 more source

Cholera Toxin Production and Localization in Vesicles of Vibrio cholerae El Tor Genovariants

Проблемы особо опасных инфекций
The aim was to assess the level of toxin production in Vibrio cholerae El Tor genovariants and to determine the localization of cholera toxin in vesicles.Materials and methods. The work is performed on typical strains and genovariants of V.
L. P. Alekseeva, O. A. Yakusheva, V. V. Evdokimova, M. G. Meloyan, V. P. Zyuzina   +4 more
doaj   +1 more source

Retention of differentiated properties in an established dog kidney epithelial cell line (MDCK). [PDF]

, 1979
Madin-Darby canine kidney (MDCK) cells grown in tissue culture have the morphological properties of distal tubular epithelial cells, form tight junctions, and lack several proximal tubular enzyme markers.
Chuman, LM, Rindler, MJ, Saier, MH, Shaffer, L   +3 more
core  

[Cholera toxin as Vibrio cholera superantigen].

Zhurnal mikrobiologii, epidemiologii i immunobiologii, 2002
Experimental data confirming our earlier suggestion, that cholerae toxin (CT) possesses superantigen (SA) properties are presented. When used in very small doses, CT has been found to induce polyclonal activation of T lymphocytes, essentially exceeding that observed in classical T mitogens characteristic of SA. CT, in contrast to mitogens and similarly
G I, Vasil'eva, V N, Kozlovskiĭ, B N, Mishan'kin, M B, Mishan'kin   +3 more
openaire   +1 more source