Results 91 to 100 of about 72,576 (226)

THE STUDY OF LYMPHOCYTE APOPTOSIS INDUCED BY VIBRIO CHOLERAE ANTIGENS IN THE FORMATION OF IMMUNODEFICIENCY AND THE POSSIBILITY OF ITS CORRECTION

Медицинский вестник Юга России, 2013
Purpose: To study the role of lymphocyte apoptosis induced by Vibrio cholerae microbial cells and cholera toxin in the formation of the postvaccinal apoptotic immunodeficiency, as well as the possibility of its correction with the use of immunomodulator ...
I. A. Ivanova, N. D. Omelchenko, N. R. Telesmanich, G. I. Vasilyeva, Ye. P. Doroshenko, I. A. Bespalova, A. K. Kiselyova, A. V. Filippenko, L. V. Sudyina, B. N. Mishankin   +9 more
doaj   +1 more source

Exploring the genetics of irritable bowel syndrome: A GWA study in the general population and replication in multinational case-control cohorts [PDF]

, 2014
OBJECTIVE: IBS shows genetic predisposition, but adequately powered gene-hunting efforts have been scarce so far. We sought to identify true IBS genetic risk factors by means of genome-wide association (GWA) and independent replication studies.
Agreus, Lars, Andreasson, Anna, Assadi, Ghazaleh, Barbara, Giovanni, Barbaro, Raffaella, Bellini, Massimo, Blandizzi, Corrado, Boeckxstaens, Guy, Bresso, Francesca, Burwinkel, Barbara, Camilleri, Michael, Colucci, Rocchina Lucia, D'Amato, Mauro, Daly, Mark J., Dlugosz, Aldona, Ek, Weronica E., Gambaccini, Dario, Gazouli, Maria, Holliday, Elizabeth G., Houghton, Lesley, Karamanolis, George, Karling, Pontus, Li, Ling, Lindberg, Greger, Magnusson, Patrik, Marchi, Santino, Niesler, Beate, Ohlsson, Bodil, Papadaki, Evangelia, Pedersen, Nancy L., Rafter, Joseph, Rappold, Gudrun, Reznichenko, Anna, Ripke, Stephan, Rivera, Natalia V., Schmidt, Peter T., Simren, Magnus, Stanghellini, Vincenzo, Surowy, Harald, Talley, Nicholas J., Tornblom, Hans, Walter, Susanna, Wouters, Mira M., Zucchelli, Marco   +43 more
core   +1 more source

RAB4A acts as a negative feedback regulator of extracellular vesicle secretion during TGF‐β signaling

The FEBS Journal, EarlyView.
TGF‐β signaling regulates extracellular vesicle (EV) release in cancer cells by modulating the expression and activity of genes associated with EV biogenesis. The TGF‐β‐induced upregulation of RAB4A expression facilitates fast endosomal recycling, a process that limits the fusion of multivesicular bodies with the plasma membrane and EV secretion. Hence,
Dorival Mendes Rodrigues‐Junior, Maria Anastasia Doumani, Hao Fu, Jelle van den Bor, Olof Idevall‐Hagren, Aristidis Moustakas   +5 more
wiley   +1 more source

Association between post-diagnostic use of cholera vaccine and risk of death in prostate cancer patients

Nature Communications, 2018
Post-diagnostic use of cholera vaccine can improve the prognosis in patients with colorectal cancer suggesting cholera toxin might have an antineoplastic effect.
Jianguang Ji, Jan Sundquist, Kristina Sundquist   +2 more
doaj   +1 more source

Posttranslational Regulation of IL-23 Production Distinguishes the Innate Immune Responses to Live Toxigenic versus Heat-Inactivated Vibrio cholerae

mSphere, 2019
Vibrio cholerae infection provides long-lasting protective immunity, while oral, inactivated cholera vaccines (OCV) result in more-limited protection. To identify characteristics of the innate immune response that may distinguish natural V.
Ana A. Weil, Crystal N. Ellis, Meti D. Debela, Taufiqur R. Bhuiyan, Rasheduzzaman Rashu, Daniel L. Bourque, Ashraful I. Khan, Fahima Chowdhury, Regina C. LaRocque, Richelle C. Charles, Edward T. Ryan, Stephen B. Calderwood, Firdausi Qadri, Jason B. Harris   +13 more
doaj   +1 more source

Integrating the Health Sector Into Nationally Determined Contributions: Challenges, Opportunities and Pathways for Climate Resilient Health Systems

Climate Resilience and Sustainability, Volume 5, Issue 1, June 2026.
This article examines how the health sector can be systematically integrated into NDCs to address climate risks. It identifies persistent challenges such as weak data, finance gaps, and institutional fragmentation, while highlighting opportunities in co‐benefits, resilient infrastructure, and cross‐sectoral collaboration.
Samwel Manyele, Honest Anicetus
wiley   +1 more source

Production and Purification of Polyclonal Antibody against Cholera Toxin

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2015
BACKGROUND AND OBJECTIVE: Cholera is a debilitating enteric disease, caused by Vibrio cholerae. Cholera toxin is the most important virulence factor in the pathogenesis of Vibrio cholera.
Shahram Nazarian, Mohammadali Arefpour, Mohammadjavad Bagheripour, gholamreza Olad   +3 more
doaj  

Recombinant Strains Application for Simultaneous Preparation of Several Purified Cholera Vibrio Antigens

Проблемы особо опасных инфекций, 2009
Proposed is the method for simultaneous isolation and purification of three cholera vibrio key pathogenicity factors (cholera toxin, toxin-co-regulated adhesion pili, O1 antigen Ogawa or Inaba), which are main protective antigens, from previously ...
T.L. Zakharova, S.P. Zadnova, L.F. Livanova, M.N. Kireev, N.I. Smirnova   +4 more
doaj   +1 more source

Effect of synthetic and bovine milk conjugated linoleic acid (CLA) on immune function : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Nutrition Science at Massey University [PDF]

, 1999
CLA is a collective name for a mixture of positional and geometrical isomers of linoleic acid (c-9, c-12-octadecadioenic acid) which possess conjugated double bonds.
Zhao, Hui
core  

Bacillus anthracis edema factor substrate specificity: evidence for new modes of action [PDF]

, 2012
Since the isolation of Bacillus anthracis exotoxins in the 1960s, the detrimental activity of edema factor (EF) was considered as adenylyl cyclase activity only.
Agrawal, Altaweel, Basler, Bauche, Bell, Benson, Beste, Bock, Bond, Boyd, Bradley, Brown, Burhenne, Carbonetti, Carbonetti, Carson-Walter, Casteel, Christensen, Christensen, Confer, Copsel, Crawford, Crowe, Cunningham, Dalkas, Defer, Deuquet, Ding, Drum, Duesbery, Feld, Firoved, Friedlander, Fu, Fukuhara, Gaion, Gille, Gordon, Göttle, Hammerschmidt, He, Helfman, Hong, Ivarsson, Jernigan, Johnson, Katayama, Katayama, Kaupp, Kintzer, Klimpel, Laine, Larabee, Larabee, Leppla, Liu, Martin Göttle, McDonough, Milne, Mogridge, Mogridge, Newton, Newton, Newton, Newton, Newton, Oncu, O´Brien, Park, Petosa, Pezard, Postea, Puhar, Roland Seifert, Santelli, Scobie, Scobie, Scorpio, Shapiro, Shen, Shirshev, Soelaiman, Stefan Dove, Sun, Tamayo, Taylor, Taylor, Tesmer, Thomas, Tournier, Vitale, Vitale, Vojtova, Yeager, Zong   +94 more
core   +2 more sources