Results 291 to 300 of about 840,802 (388)

Tumor microenvironment in gastric cancer immune tolerance and its therapeutic relevance in immunomodulation (Review). [PDF]

Oncol Lett
Guan Z, Han L, Chen B, Ma Y, Ni Q, Wang Z, Yang J, Liu Z.   +7 more
europepmc   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Tumor Immunotherapy and Microbiome: From Bench-to-Bedside Applications. [PDF]

MedComm (2020)
Lin A, Xiong M, Jiang A, Chen L, Huang L, Li K, Wong HZH, Zhang J, Liu Z, Cheng Q, Tang B, Zhang P, Luo P.   +12 more
europepmc   +1 more source

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

Advanced Healthcare Materials, EarlyView.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement, Jana Ismail, Josefine Schroeder, Amod Godbole, Johanna Schreiber, Christine Weber, Zoltan Cseresnyes, Marc T. Figge, Bettina Löffler, Ulrich S. Schubert, Stephanie Schubert, Christina Ehrhardt, Carsten Hoffmann   +12 more
wiley   +1 more source

Cytokine Engineering in CAR-T Cell Therapy: Next-Generation Strategies. [PDF]

Immune Netw
Kim S, Heo SH, Baek H, Hwang SS.
europepmc   +1 more source

Figure S5 from Inhibition of METTL3 Results in a Cell-Intrinsic Interferon Response That Enhances Antitumor Immunity [PDF]

Andrew A. Guirguis, Yaara Ofir-Rosenfeld, Kathy Knezevic, Wesley Blackaby, David Hardick, Yih-Chih Chan, Ali Motazedian, Andrea Gillespie, Dane Vassiliadis, Enid Y.N. Lam, Kevin Tran, Byron Andrews, Michael E. Harbour, Lina Vasiliauskaitė, Claire J. Saunders, Georgia Tsagkogeorga, Aleksandra Azevedo, Joanna Obacz, Ewa S. Pilka, Marie Carkill, Laura MacPherson, Elanor N. Wainwright, Brian Liddicoat, Benjamin J. Blyth, Mark R. Albertella, Oliver Rausch, Mark A. Dawson   +26 more
openalex   +1 more source

Delivery of Multifunctional Microspheres via Intravesical Instillation for Bladder Carcinoma: Therapeutic Potential and Mechanistic Insights

Advanced Healthcare Materials, EarlyView.
PCTM microspheres were successfully synthesized using microfluidic and click chemistry techniques.In Vivo and in vitro experiments have shown that PCTM microspheres have obvious targeting, adhesion, membrane penetration and anti‐tumor properties for bladder tumors.The antitumor mechanism of PCTM microspheres is to indirectly induce S‐stage blockage of ...
Zhaoxiang Lu, Wentie Yang, Youzhi Hong, Yusen Qiao, Chaozhao Liang   +4 more
wiley   +1 more source

Oncolytic virus therapy for osteosarcoma: mechanisms, opportunities, and challenges. [PDF]

Front Immunol
Wang JW, Ge X, Liu JH, Zhang X.
europepmc   +1 more source

A Biomimetic Buffering Hydrogel Scaffold for Long‐Term Culture of Patient‐Derived Tumor Organoids

Advanced Healthcare Materials, EarlyView.
A biomimetic fibrous buffering hydrogel controls the local acidification at the tumoroid/hydrogel interface at the physiologically relevant level over 21‐day culture. The buffering effect promotes cancer cell proliferation in the tumoroids and supports the structural integrity and mechanical properties of the hydrogel scaffold over long‐term tumoroid ...
Elizaveta Gusarova, Fatemeh Ahmadi, Jennifer Cruickshank, Zheyuan Miao, David W. Cescon, Eugenia Kumacheva   +5 more
wiley   +1 more source

Ginsenoside Rh2- functionalized liposomes enhanced BRD4-PROTAC delivery and antitumor efficacy <i>via</i> improved tumor targeting and ECM remodeling. [PDF]

Mater Today Bio
Wen L, Rao J, Chen J, Li F, Chen X, Guo S, Cui B, Qiu C, Chen W.   +8 more
europepmc   +1 more source