Results 251 to 260 of about 112,335 (304)

Potent and selective LSD1 inhibitor DC551040 reveals a promising combination therapy for AML with insight into epigenetic dysregulation. [PDF]

open access: yesSignal Transduct Target Ther
Wang J   +24 more
europepmc   +1 more source

Exploratory high-throughput screening of repurposed drugs for canine lymphoid malignancies. [PDF]

open access: yesBMC Vet Res
Nishida M   +7 more
europepmc   +1 more source

Tumor-specific GPX4 degradation enhances ferroptosis-initiated antitumor immune response in mouse models of pancreatic cancer

Science Translational Medicine, 2023
Lipid peroxidation–dependent ferroptosis has become an emerging strategy for tumor therapy. However, current strategies not only selectively induce ferroptosis in malignant cells but also trigger ferroptosis in immune cells simultaneously, which can ...
Jingbo Li   +9 more
semanticscholar   +1 more source

Identification of Novel CD39 Inhibitors Based on Virtual Screening and Enzymatic Assays

Journal of Chemical Information and Modeling, 2021
The accumulation of adenosine in the tumor microenvironment mediates immunosuppression and promotes tumor growth and proliferation. Intervention of the adenosine pathway is an important direction of antitumor immunity research.
Yunshuo Zhao   +7 more
semanticscholar   +1 more source

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