Results 261 to 270 of about 17,918 (294)

Venoms, antivenoms and immunotherapy

Toxicon, 1998
A century after the discovery of antivenom and despite real progress undertaken in its manufacture, its use remains largely empirical. Recent studies of pharmacokinetics of envenoming permitted improved understanding of immunotherapy. Improved purification of the antivenom by using immunoglobulin fragments has lead to increased tolerance and efficiency
/Chippaux, Jean-Philippe, Goyffon, M.
openaire   +3 more sources

Snake antivenom trial

Veterinary Record, 2014
WE would like to invite veterinary practitioners to take part in a clinical trial of Europe's first dedicated veterinary snake antivenom, ViperaVet. This is directed against the venom of four medically important Vipera species found throughout western Europe, including the adder ( Vipera berus) , Britain's only native venomous snake. Between September
Fiona M.S. Bolton, Nicholas R. Casewell, Ibrahim Al-Abdulla   +2 more
openaire   +3 more sources

Bothrops snakebites in the Amazon: recovery from hemostatic disorders after Brazilian antivenom therapy

Clinical toxicology, 2020
Introduction: Bothrops atrox snakebites are a major public health problem in the Amazon region and also cause hemostatic disorders. In this study, we assessed the recovery from hemostatic disorders in Bothrops snakebite patients after being given ...
Sâmella Silva de Oliveira, Eliane Campos Alves, Alessandra Dos Santos Santos, Elizandra Freitas Nascimento, João Pedro Tavares Pereira, Iran Mendonça da Silva, Jacqueline A G Sachett, Hiochelson Najibe Dos Santos Ibiapina, Lybia Kássia Santos Sarraf, Jorge Carlos Contreras Bernal, L. A. Freitas de Sousa, M. Colombini, Hedylamar Oliveira Marques, Marcus Vinícius Guimarães de Lacerda, A. Moura-da-Silva, Hui Wen Fan, Luiz Carlos de Lima Ferreira, Ida Sigueko Sano Martins, W. Monteiro   +18 more
semanticscholar   +1 more source

Antivenom Therapy in the Americas

Drugs, 1999
Envenomations are an important cause of injury in the Americas. While supportive care alone may result in an acceptable outcome, antivenom offers a specific therapy that can significantly reduce the injury and symptoms of the envenomation. Antivenoms are hyperimmune sera collected from animals immunised with venom. The antibodies contained in the serum
Richard C. Dart, Gerald F. O'Malley, Kennon Heard   +2 more
openaire   +2 more sources

Antivenoms and Coagulation

2010
The treatment of snake envenomations has been a complicated battle for over a century. Since the development of antivenoms, inevitably fatal venoms have decreased to rarely fatal provided that antivenom is administered early. Snake venoms contain many molecules that act directly at the site of the bite, while others set off cascades of reactions ...
Elda E. Sánchez, Esteban Cantu, Belsy Guerrero, Alexis Rodríguez-Acosta   +3 more
openaire   +2 more sources

Toxin-resolved antivenomics-guided assessment of the immunorecognition landscape of antivenoms

Toxicon, 2018
Snakebite envenoming represents a major issue in rural areas of tropical and subtropical regions across sub-Saharan Africa, South to Southeast Asia, Latin America and Oceania. Antivenoms constitute the only scientifically validated therapy for snakebite envenomings, provided they are safe, effective, affordable, accessible and administered ...
Juan J. Calvete, Yania Rodríguez, Sarai Quesada-Bernat, Davinia Pla   +3 more
openaire   +2 more sources

Failure of a Mexican antivenom on recovery from snakebite-related coagulopathy in French Guiana

Clinical toxicology, 2020
Introduction In French Guiana, most snakebites are caused by crotalids, with the main signs being tissue damage and bleeding due to venom-induced coagulopathy.
X. Heckmann, V. Lambert, G. Mion, A. Ehrhardt, C. Marty, F. Perotti, J. Carod, A. Jolivet, D. Boels, Ibrahim Lehida Andi, S. Larréché   +10 more
semanticscholar   +1 more source

Immunoreactivity and neutralization capacity of Philippine cobra antivenom against Naja philippinensis and Naja samarensis venoms.

Transactions of the Royal Society of Tropical Medicine and Hygiene, 2020
BACKGROUND The Philippine cobra (Naja philippinensis) and Samar cobra (Naja samarensis) are two WHO Category 1 medically important venomous snakes in the Philippines.
Choo Hock Tan, Praneetha Palasuberniam, Francis Bonn Blanco, K. Y. Tan   +3 more
semanticscholar   +1 more source

Antivenom, anecdotes and evidence

Medical Journal of Australia, 2004
Envenoming is rare in Australia - multicentre studies are needed to improve the tenuous evidence base.
openaire   +3 more sources

Systematic review and meta-analysis on the efficacy of Indian polyvalent antivenom against the Indian snakes of clinical significance

Archives of Toxicology, 2023
Gayathri Gopal, Harish Selvaraj, Suresh Krishna Venkataramanan, Saraswathi Venkataraman, Keerthana Saravanan, Catherine Bibina, S. V. Ambi   +6 more
semanticscholar   +1 more source