Pharmacokinetics of Snake Venom [PDF]
Toxins, 2018 Understanding snake venom pharmacokinetics is essential for developing risk assessment strategies and determining the optimal dose and timing of antivenom required to bind all venom in snakebite patients. This review aims to explore the current knowledge of snake venom pharmacokinetics in animals and humans.
Stephen Duffull +2 more
exaly +4 more sources
Hemostasis-Modulating Proteins from Indian Elapid and Viper Snake Venom: Mechanistic Insights and Therapeutic Opportunities [PDF]
LifeSnake venom is a complex cocktail of biologically active proteins and peptides with highly specific physiological activities, yet its therapeutic potential remains largely unexplored.
Shanmugaraja Kiruthika +4 more
doaj +2 more sources
Innovations in Snake Venom-Derived Therapeutics: A Systematic Review of Global Patents and Their Pharmacological Applications [PDF]
ToxinsActive compounds from natural sources, particularly snake venoms, are crucial for pharmaceutical development despite challenges in drug discovery. Snake venoms, historically used for medicinal purposes, contain bioactive peptides and enzymes that show ...
Diana Carolina Zona Rubio +2 more
doaj +2 more sources
Emerging Trends in Snake Venom-Loaded Nanobiosystems for Advanced Medical Applications: A Comprehensive Overview [PDF]
PharmaceuticsAdvances in medical nanobiotechnology have notably enhanced the application of snake venom toxins, facilitating the development of new therapies with animal-derived toxins.
Álisson E. F. Alves +10 more
doaj +2 more sources
Description of the antipredatory head-wobble behaviour in Chilean rear-fanged snakes Tachymenis peruviana Wiegmann, 1835 and Tachymenis chilensis coronellina Werner, 1898 (Serpentes, Dipsadidae) [PDF]
Herpetozoa, 2022 In this work, we describe the first records of head-wobble behaviour for Tachymenis peruviana and T. chilensis coronellina. We analyse this behaviour (occurrence, frequency) and accompanying displays in both species. Of particular note is that T.
Claudio Reyes-Olivares +3 more
doaj +3 more sources
First record of the invasive gecko, Lepidodactylus lugubris Duméril & Bibron, 1836 in mainland Chile (Squamata, Gekkonidae) [PDF]
Herpetozoa, 2020 In Chile, the presence of Mourning Gecko, Lepidodactylus lugubris Duméril & Bibron, 1836 has been recognized for Easter Island (Rapa Nui) from late 19th century. Here, we report the first observation of a juvenile specimen of L.
Felix A. Urra +3 more
doaj +3 more sources
Frontiers in Cell and Developmental Biology, 2021 The role of metabolism in tumor growth and chemoresistance has received considerable attention, however, the contribution of mitochondrial bioenergetics in migration, invasion, and metastasis is recently being understood.
Félix A. Urra +11 more
doaj +1 more source
Pharmaceutics, 2023 From the venom of the Bothrops pictus snake, an endemic species from Peru, we recently have described toxins that inhibited platelet aggregation and cancer cell migration.
Dan E. Vivas-Ruiz +21 more
doaj +1 more source
Leucism and albinism in the rear-fanged snakes Tachymenis chilensis chilensis (Schlegel, 1837) and Tachymenis chilensis coronellina Werner, 1898 (Serpentes, Dipsadidae) [PDF]
Herpetozoa, 2021 Herein, we report the first observation of two different coloration patterns in Chilean snakes. Based on the alteration of wild coloration patterns, a juvenile specimen of Tachymenis chilensis coronellina Werner, 1898 was diagnosed with albinism and a ...
Felix A. Urra +6 more
doaj +3 more sources
An Emergent Role for Mitochondrial Bioenergetics in the Action of Snake Venom Toxins on Cancer Cells
Frontiers in Oncology, 2022 Beyond the role of mitochondria in apoptosis initiation/execution, some mitochondrial adaptations support the metastasis and chemoresistance of cancer cells. This highlights mitochondria as a promising target for new anticancer strategies.
Félix A. Urra +9 more
doaj +1 more source