Results 201 to 210 of about 928,338 (389)

ANTIVIRAL PROPERTIES OF p-ALKYLEPHEDRINE AND p-ALKYLNOREPHEDRINE

, 1959
Takeo Ueda, Shigeshi Toyoshima, Kiyoshi Takahashi, Masako Muraoka   +3 more
openalex   +2 more sources

Antiviral Actions of Interferons

Clinical Microbiology Reviews, 2001
C. E. Samuel
semanticscholar   +1 more source

COVID-19: combining antiviral and anti-inflammatory treatments

Lancet. Infectious Diseases (Print), 2020
J. Stebbing, A. Phelan, Ivan Griffin, C. Tucker, O. Oechsle, Daniel P. Smith, Peter J. Richardson   +6 more
semanticscholar   +1 more source

ADAR1 as a Placental Innate Immune Rheostat Sustaining the Homeostatic Balance of Intrinsic Interferon Response at the Maternal‐Fetal Interface

Advanced Science, EarlyView.
This study reveals that ADAR1, an RNA‐editing enzyme, fine‐tunes immune responses in the placenta by preventing the accumulation of immunogenic double‐stranded RNAs (dsRNAs) from interferon‐stimulated genes. The loss of ADAR1 in the placenta leads to excessive interferon signaling restricted to the junctional zone, disrupting placental development and ...
Xiaogang Chen, Xiangchao Xu, Jiahao Chen, Huiru Zhang, Wanshan Zheng, Wenzhe Yu, Xiaoqian Hu, Bin Cao   +7 more
wiley   +1 more source

Comparison of the Antiviral Activity in vitro of some Non-steroidal Anti-inflammatory Drugs

, 1969
Anna D. Inglot
openalex   +1 more source

Post‐Translational Modifications of TOE3 Regulate Antiviral Defense in Tobacco

Advanced Science, EarlyView.
CK2αL phosphorylates TOE3 and enhances its stability, while FBXL1 promotes the ubiquitination‐degradation of TOE3 via the 26S proteasome. Compared to CK2αL‐phosphorylated TOE3, nonphosphorylated TOE3 shows a much higher affinity for FBXL1 and is more susceptible to ubiquitination‐degradation, thus facilitating viral infection. The regulatory mechanisms
Bolei Jiao, Baijun Wu, Honghui Lin, Dehui Xi   +3 more
wiley   +1 more source

Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses

Science Translational Medicine, 2017
T. Sheahan, A. Sims, Rachel L. Graham, Vineet D. Menachery, Lisa E. Gralinski, J. Case, S. Leist, K. Pyrć, Joy Y. Feng, Iva Trantcheva, R. Bannister, Yeojin Park, D. Babusis, M. Clarke, R. Mackman, Jamie E. Spahn, Christopher A. Palmiotti, D. Siegel, A. Ray, T. Cihlář, R. Jordan, M. Denison, R. Baric   +22 more
semanticscholar   +1 more source

TWF2 Drives Tumor Progression and Sunitinib Resistance in Renal Cell Carcinoma through Hippo Signaling Suppression

Advanced Science, EarlyView.
Twinfilin actin‐binding protein (TWF2) is upregulated in sunitinib‐resistant renal cell carcinoma (RCC) cells, where it interacts with YAP and protects YAP from degradation. Stabilized YAP translocates into the nucleus and activates transcription of target genes, promoting RCC progression and drug resistance.
Liangmin Fu, Wuyuan Liao, Youyan Tan, Hansen Lin, Kun Ye, Xinwei Zhou, Mingjie Lin, Kangbo Huang, Minyu Chen, Jietao Wei, Haoqian Feng, Yuhang Chen, Jinwei Chen, Bohong Guan, Shan Li, Zhengkun Zhang, Anze Yu, Zihao Feng, Lizhen Zhang, Guannan Shu, Jun Lu, Wei Chen, Yihui Pan, Jiefeng Yang, Junhang Luo, Li Luo   +25 more
wiley   +1 more source

Isolation of Variant Strains from Foot-and-Mouth Disease Virus Propagated in Cell Cultures Containing Antiviral Sera

, 1965
N. St. G. Hyslop
openalex   +1 more source

T2T Genomes Unveil Centromere Architecture and Adaptive Divergence in Large Yellow Croaker (Larimichthys crocea)

Advanced Science, EarlyView.
This study presents telomere‐to‐telomere genome assemblies for two populations of Larimichthys crocea. We identified centromere‐specific tandem repeats invaded by LTR/ERV1 retrotransposons, unique 5S rRNA enrichment patterns, and population‐specific structural variants. Comparative genomic analyses further reveal distinct adaptive mechanisms in the MYD
Yu Cui, Yingbo Yuan, Bi Wang, Baolan Wu, Mingyi Cai, Ming Fang, Weiliang Shen, Xiongfei Wu, Fang Han, Zhiyong Wang   +9 more
wiley   +1 more source