Results 211 to 220 of about 928,338 (389)
Advanced Science, EarlyView.Understanding the virus‐host arms race has been a fascinating topic in virology; contributing significantly to the development of treatments and control strategies for viral diseases. CHV1 employs a sophisticated counter‐defense mechanism in its fungal host by utilizing a viral silencing suppressor to inhibit fungal FMN reductase; thereby modulating ...
Shiyu Zhai +8 more
wiley +1 more source
Coronavirus membrane fusion mechanism offers a potential target for antiviral development
Antiviral Research, 2020 Tiffany Tang +4 more
semanticscholar +1 more source
NamiRNA‐Enhancer Network: The Changing Era Challenge and Chance of miRNA
Advanced Science, EarlyView.MiRNAs (miRNAs) regulate diverse biological processes across species. Unlike canonical miRNA‐mediated gene repression, Nuclear Activating miRNAs (NamiRNAs) can efficiently upregulate gene expression by targeting enhancers. This review systematically summarizes recent advances in NamiRNA research, elucidates the theory of NamiRNA‐Enhancer‐mediated Gene ...
Lu Chen +13 more
wiley +1 more source
Gigaxonin Potentiates Antiviral Innate Immune Responses by Targeting cGAS and TREX1
Advanced Science, EarlyView.TREX1 antagonizes DNA sensor cGAS by degrading cytosolic DNA. This work identifies gigaxonin as a molecular switch that coordinates DNA sensing and clearance pathways to amplify antiviral responses. Under the steady state, gigaxonin maintains cellular homeostasis by mediating TREX1 ubiquitination and proteasomal degradation. During DNA virus infection,
Ben‐Zhe Ji +9 more
wiley +1 more source
Studies on Antiviral and Antitumor Antibiotics
, 1969 Akira Takatsuki +4 more
openalex +4 more sources
Studies on Antiviral Agents. V. Synthesis and Antiviral Activity of N-Chloro Compounds.
, 1967 Hidetaka Yuki +5 more
openalex +2 more sources
Targeting HDAC and PARP Enhances STING‐Dependent Antitumor Immunity in STING‐Deficient Tumor
Advanced Science, EarlyView.Dual HDAC and PARP inhibition restores STING signaling, enhances interferon response, and boosts antitumor immunity in STING‐deficient tumors. . Abstract The stimulator of interferon genes (STING)‐mediated innate immune pathway plays an important role in tumor immunosurveillance.
Chengzhou Mao +10 more
wiley +1 more source
Synthesis and Antiviral Effect of Alkylated Barbituric Acid
, 1961 Toyoharu Mizuma +2 more
openalex +2 more sources